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The map label for this gene is mtgA

Identifier: 157162692

GI number: 157162692

Start: 3400008

End: 3400736

Strand: Reverse

Name: mtgA

Synonym: EcHS_A3401

Alternate gene names: 157162692

Gene position: 3400736-3400008 (Counterclockwise)

Preceding gene: 157162693

Following gene: 157162679

Centisome position: 73.24

GC content: 51.99

Gene sequence:

>729_bases
ATGAGTAAAAGCCGCTTAACGGTGTTTAGTTTCGTTCGCCGTTTTCTTTTGCGGTTAATGGTTGTCCTCGCCGTTTTCTG
GGGCGGGGGCATCGCGTTGTTTAGCGTTGCGCCTGTTCCCTTCTCAGCGGTAATGGTCGAGCGACAGGTCAGCGCCTGGC
TGCATGGCAATTTTCGTTACGTGGCACATTCTGACTGGGTCAGTATGGATCAAATCTCGCCGTGGATGGGACTGGCGGTG
ATTGCCGCAGAAGATCAGAAATTTCCTGAGCACTGGGGCTTTGATGTCGCTTCCATTGAGAAAGCCCTGGCGCACAACGA
GCGCAATGAAAACCGTATTCGCGGTGCTTCAACGATTTCTCAACAGACAGCCAAAAATCTCTTTTTATGGGATGGGCGTA
GCTGGGTTCGAAAAGGGCTGGAAGCCGGATTAACGCTGGGGATAGAAACGGTCTGGAGCAAAAAGCGTATCCTGACGGTT
TACCTGAATATCGCCGAATTTGGCGACGGTGTGTTTGGCGTCGAAGCTGCGGCACAACGTTATTTCCACAAACCCGCGAG
CAAACTTACCCGGTCGGAAGCTGCATTACTGGCAGCTGTATTACCTAATCCACTTCGTTTCAAAGTCTCCTCGCCATCGG
GCTACGTGCGTAGCCGTCAGGCGTGGATTTTACGGCAGATGTATCAGTTAGGCGGTGAGCCGTTTATGCAACAACACCAG
CTGGATTAA

Upstream 100 bases:

>100_bases
ATAAGATTGTCACCACCCCAGCATATATGCTGGCGCAGAACATTGCAGAAGCGGCGAGCGGCATTGATAAGCTGGTTTCC
CGCGTGCTGGTTCTGGCTGA

Downstream 100 bases:

>100_bases
GCTTCGCGCGAAGTGAGGGCCAGCGTTTTGCTCTCACGAGGTTGCAGATCTTTCTGCAGGGCAATAGCCAGCGCCGGTTG
GGCGATAAATCGTTTCCATA

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSKSRLTVFSFVRRFLLRLMVVLAVFWGGGIALFSVAPVPFSAVMVERQVSAWLHGNFRYVAHSDWVSMDQISPWMGLAV
IAAEDQKFPEHWGFDVASIEKALAHNERNENRIRGASTISQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTV
YLNIAEFGDGVFGVEAAAQRYFHKPASKLTRSEAALLAAVLPNPLRFKVSSPSGYVRSRQAWILRQMYQLGGEPFMQQHQ
LD

Sequences:

>Translated_242_residues
MSKSRLTVFSFVRRFLLRLMVVLAVFWGGGIALFSVAPVPFSAVMVERQVSAWLHGNFRYVAHSDWVSMDQISPWMGLAV
IAAEDQKFPEHWGFDVASIEKALAHNERNENRIRGASTISQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTV
YLNIAEFGDGVFGVEAAAQRYFHKPASKLTRSEAALLAAVLPNPLRFKVSSPSGYVRSRQAWILRQMYQLGGEPFMQQHQ
LD
>Mature_241_residues
SKSRLTVFSFVRRFLLRLMVVLAVFWGGGIALFSVAPVPFSAVMVERQVSAWLHGNFRYVAHSDWVSMDQISPWMGLAVI
AAEDQKFPEHWGFDVASIEKALAHNERNENRIRGASTISQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTVY
LNIAEFGDGVFGVEAAAQRYFHKPASKLTRSEAALLAAVLPNPLRFKVSSPSGYVRSRQAWILRQMYQLGGEPFMQQHQL
D

Specific function: Cell wall formation

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family

Homologues:

Organism=Escherichia coli, GI1789601, Length=242, Percent_Identity=100, Blast_Score=494, Evalue=1e-141,
Organism=Escherichia coli, GI87082258, Length=176, Percent_Identity=37.5, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786343, Length=127, Percent_Identity=37.007874015748, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788867, Length=144, Percent_Identity=33.3333333333333, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTGA_ECO24 (A7ZSA7)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001464686.1
- ProteinModelPortal:   A7ZSA7
- SMR:   A7ZSA7
- STRING:   A7ZSA7
- EnsemblBacteria:   EBESCT00000022769
- GeneID:   5588817
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_3695
- eggNOG:   COG0744
- GeneTree:   EBGT00050000008951
- HOGENOM:   HBG685698
- OMA:   QIALWSF
- ProtClustDB:   PRK00056
- BioCyc:   ECOL331111:ECE24377A_3695-MONOMER
- HAMAP:   MF_00766
- InterPro:   IPR001264
- InterPro:   IPR011812
- TIGRFAMs:   TIGR02070

Pfam domain/function: PF00912 Transgly

EC number: 2.4.2.- [C]

Molecular weight: Translated: 27342; Mature: 27211

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x17582d70)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSRLTVFSFVRRFLLRLMVVLAVFWGGGIALFSVAPVPFSAVMVERQVSAWLHGNFRY
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEE
VAHSDWVSMDQISPWMGLAVIAAEDQKFPEHWGFDVASIEKALAHNERNENRIRGASTIS
EEECCCCCHHHCCCCCCEEEEEECCCCCCHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHH
QQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTVYLNIAEFGDGVFGVEAAAQR
HHHHCCEEEECCHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEEHHHHCCCCHHHHHHHHH
YFHKPASKLTRSEAALLAAVLPNPLRFKVSSPSGYVRSRQAWILRQMYQLGGEPFMQQHQ
HHHCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHCC
LD
CH
>Mature Secondary Structure 
SKSRLTVFSFVRRFLLRLMVVLAVFWGGGIALFSVAPVPFSAVMVERQVSAWLHGNFRY
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEE
VAHSDWVSMDQISPWMGLAVIAAEDQKFPEHWGFDVASIEKALAHNERNENRIRGASTIS
EEECCCCCHHHCCCCCCEEEEEECCCCCCHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHH
QQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTVYLNIAEFGDGVFGVEAAAQR
HHHHCCEEEECCHHHHHHHHHCCHHHHHHHHHCCCEEEEEEEEHHHHCCCCHHHHHHHHH
YFHKPASKLTRSEAALLAAVLPNPLRFKVSSPSGYVRSRQAWILRQMYQLGGEPFMQQHQ
HHHCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHCC
LD
CH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA