Click here to switch to the map view.

The map label for this gene is kbaZ [H]

Identifier: 157162615

GI number: 157162615

Start: 3327534

End: 3328814

Strand: Direct

Name: kbaZ [H]

Synonym: EcHS_A3322

Alternate gene names: 157162615

Gene position: 3327534-3328814 (Clockwise)

Preceding gene: 157162613

Following gene: 157162616

Centisome position: 71.66

GC content: 54.96

Gene sequence:

>1281_bases
GTGAAACATCTAACAGAAATGGTGAGACAGCACAAAGCGGGCAAAACAAATGCAATTTATGCCGTTTGTTCCGCACATCC
GCTGGTGCTGGAAGCTGCAATCCGCTACGCCAGTGCAAACCAAACGCCGTTACTGATTGAAGCAACCTCCAATCAGGTAG
ACCAGTTCGGCGGTTATACCGGAATGACGCCCGCCGATTTTCGCGGCTTTGTTTGTCAGCTCGCCGACTCGTTGAATTTC
CCGCAGGATGCGTTGATTCTGGGTGGTGACCATCTGGGGCCAAACCGCTGGCAAAACCTGCCAGCCGCTCAGGCAATGGC
CAATGCCGATGATTTGATTAAAAGCTACGTTGCGGCAGGATTCAAAAAAATCCACCTTGATTGCAGCATGTCCTGTCAGG
ACGATCCAATTCCCTTAACTGATGACATCGTGGCTGAACGCGCCGCCCGTCTGGCGAAAGTGGCGGAAGAAACCTGTCTT
GAACACTTTGGCGAAGCCGATCTGGAGTATGTCATTGGTACCGAAGTGCCGGTACCTGGCGGCGCGCATGAAACCTTAAG
CGAGCTGGCGGTCACCACGCCGGATGCCGCCCGCGCCACGCTGGAAGCCCATCGTCACGCCTTTGAAAAGCAAGGTTTGA
ATGCCATCTGGCCACGCATCATTGCCCTGGTGGTTCAACCCGGCGTCGAATTCGATCACACCAACGTTATTGATTATCAG
CCCGCCAAAGCGAGCGCCTTAAGCCAGATGGTCGAAAACTACGAAACGCTGATTTTCGAAGCGCACTCTACCGATTATCA
AACGCCGCAATCGCTGCGCCAGCTGGTGATTGACCACTTTGCCATTCTGAAAGTTGGCCCAGCGCTGACCTTCGCCCTGC
GTGAAGCTCTGTTCTCTCTGGCGGCGATTGAAGAAGAACTGGTGCCAGCGAAAGTCTGTTCTGGTCTGCGTCAGGTGCTG
GAAGACGTGATGCTCGACCGCCCGGAATACTGGCAAAGCCACTACCACGGTGACGGCAACGCGCGTCGTCTGGCGCGTGG
TTATAGCTACTCGGATCGCGTGCGCTATTACTGGCCGGACAGCCAGATTGATGACGCTTTCGCTCATCTGGTACGTAATC
TGGCGGATTCACCAATTCCGCTGCCGCTGATCAGCCAGTATCTGCCGCTGCAGTACGTGAAAGTTCGCTCCGGCGAGCTG
CAGCCAACGCCACGGGAACTCATTATCAACCATATTCAGGACATCCTGGCGCAGTACCACACAGCCTGTGAAGGCCAATA
A

Upstream 100 bases:

>100_bases
AAACTATTGTCTTTCGTTTTATTTTTATCTCACCATGACGCAGTATCAACTGAAACAAAACGAAAGATTAATATCGCAGT
AATCTGAACTGGAGAGGAAA

Downstream 100 bases:

>100_bases
GCAAAACAAAGAGGAACACGCTATGCCAAATATTGTTTTAAGCCGGATTGATGAACGCTTGATTCACGGTCAGGTCGGCG
TTCAATGGGTCGGATTTGCG

Product: D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit

Products: ADP; D-tagatose 1,6-bisphosphate

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MKHLTEMVRQHKAGKTNAIYAVCSAHPLVLEAAIRYASANQTPLLIEATSNQVDQFGGYTGMTPADFRGFVCQLADSLNF
PQDALILGGDHLGPNRWQNLPAAQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCL
EHFGEADLEYVIGTEVPVPGGAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWPRIIALVVQPGVEFDHTNVIDYQ
PAKASALSQMVENYETLIFEAHSTDYQTPQSLRQLVIDHFAILKVGPALTFALREALFSLAAIEEELVPAKVCSGLRQVL
EDVMLDRPEYWQSHYHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQYVKVRSGEL
QPTPRELIINHIQDILAQYHTACEGQ

Sequences:

>Translated_426_residues
MKHLTEMVRQHKAGKTNAIYAVCSAHPLVLEAAIRYASANQTPLLIEATSNQVDQFGGYTGMTPADFRGFVCQLADSLNF
PQDALILGGDHLGPNRWQNLPAAQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCL
EHFGEADLEYVIGTEVPVPGGAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWPRIIALVVQPGVEFDHTNVIDYQ
PAKASALSQMVENYETLIFEAHSTDYQTPQSLRQLVIDHFAILKVGPALTFALREALFSLAAIEEELVPAKVCSGLRQVL
EDVMLDRPEYWQSHYHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQYVKVRSGEL
QPTPRELIINHIQDILAQYHTACEGQ
>Mature_426_residues
MKHLTEMVRQHKAGKTNAIYAVCSAHPLVLEAAIRYASANQTPLLIEATSNQVDQFGGYTGMTPADFRGFVCQLADSLNF
PQDALILGGDHLGPNRWQNLPAAQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCL
EHFGEADLEYVIGTEVPVPGGAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWPRIIALVVQPGVEFDHTNVIDYQ
PAKASALSQMVENYETLIFEAHSTDYQTPQSLRQLVIDHFAILKVGPALTFALREALFSLAAIEEELVPAKVCSGLRQVL
EDVMLDRPEYWQSHYHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQYVKVRSGEL
QPTPRELIINHIQDILAQYHTACEGQ

Specific function: Component of the tagatose-1,6-bisphosphate aldolase kbaYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of kbaY. When expressed alone, kbaZ does not show any aldol

COG id: COG4573

COG function: function code G; Predicted tagatose 6-phosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gatZ/kbaZ family. KbaZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789520, Length=426, Percent_Identity=99.5305164319249, Blast_Score=880, Evalue=0.0,
Organism=Escherichia coli, GI1788411, Length=420, Percent_Identity=52.8571428571429, Blast_Score=439, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012062 [H]

Pfam domain/function: PF08013 Tagatose_6_P_K [H]

EC number: 2.7.1.144

Molecular weight: Translated: 47235; Mature: 47235

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHLTEMVRQHKAGKTNAIYAVCSAHPLVLEAAIRYASANQTPLLIEATSNQVDQFGGYT
CCHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCCC
GMTPADFRGFVCQLADSLNFPQDALILGGDHLGPNRWQNLPAAQAMANADDLIKSYVAAG
CCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHCCCHHHHHCCHHHHHHHHHHCC
FKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCLEHFGEADLEYVIGTEVPVPG
HHEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCC
GAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWPRIIALVVQPGVEFDHTNVIDYQ
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
PAKASALSQMVENYETLIFEAHSTDYQTPQSLRQLVIDHFAILKVGPALTFALREALFSL
CHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAIEEELVPAKVCSGLRQVLEDVMLDRPEYWQSHYHGDGNARRLARGYSYSDRVRYYWPD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHCCCCCCCEEEECCC
SQIDDAFAHLVRNLADSPIPLPLISQYLPLQYVKVRSGELQPTPRELIINHIQDILAQYH
CCHHHHHHHHHHHHCCCCCCHHHHHHHCCHHEEEECCCCCCCCHHHHHHHHHHHHHHHHH
TACEGQ
HHCCCC
>Mature Secondary Structure
MKHLTEMVRQHKAGKTNAIYAVCSAHPLVLEAAIRYASANQTPLLIEATSNQVDQFGGYT
CCHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCCC
GMTPADFRGFVCQLADSLNFPQDALILGGDHLGPNRWQNLPAAQAMANADDLIKSYVAAG
CCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHCCCHHHHHCCHHHHHHHHHHCC
FKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCLEHFGEADLEYVIGTEVPVPG
HHEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCC
GAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWPRIIALVVQPGVEFDHTNVIDYQ
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
PAKASALSQMVENYETLIFEAHSTDYQTPQSLRQLVIDHFAILKVGPALTFALREALFSL
CHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAIEEELVPAKVCSGLRQVLEDVMLDRPEYWQSHYHGDGNARRLARGYSYSDRVRYYWPD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHCCCCCCCEEEECCC
SQIDDAFAHLVRNLADSPIPLPLISQYLPLQYVKVRSGELQPTPRELIINHIQDILAQYH
CCHHHHHHHHHHHHCCCCCCHHHHHHHCCHHEEEECCCCCCCCHHHHHHHHHHHHHHHHH
TACEGQ
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-tagatose 6-phosphate

Specific reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate

General reaction: Phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA