| Definition | Escherichia coli HS, complete genome. |
|---|---|
| Accession | NC_009800 |
| Length | 4,643,538 |
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The map label for this gene is yghA
Identifier: 157162481
GI number: 157162481
Start: 3194493
End: 3195377
Strand: Direct
Name: yghA
Synonym: EcHS_A3182
Alternate gene names: 157162481
Gene position: 3194493-3195377 (Clockwise)
Preceding gene: 157162479
Following gene: 157162485
Centisome position: 68.79
GC content: 54.35
Gene sequence:
>885_bases ATGTCTCATTTAAAAGACCCGACCACGCAGTATTACACTGGTGAATATCCCAAACAGAAACAACCGACGCCAGGCATCCA GGCGAAGATGACACCGGTACCGGATTGCGGCGAGAAAACCTATGTTGGTAGCGGTCGCCTGAAAGATCGTAAAGCACTGG TGACAGGGGGCGATTCCGGAATAGGTCGCGCTGCCGCCATCGCTTACGCGCGTGAAGGGGCTGACGTGGCGATCAGTTAT CTTCCCGTGGAAGAAGAAGACGCTCAGGATGTGAAAAAGATCATTGAAGAATGCGGACGCAAAGCCGTTCTGCTGCCAGG CGATTTAAGCGATGAGAAATTTGCCCGTTCGCTGGTTCACGAAGCGCACAAGGCGTTAGGCGGGCTGGATATTATGGCGC TGGTCGCCGGGAAACAGGTTGCCATTCCGGATATTGCAGACCTCACCAGCGAACAGTTTCAAAAGACCTTTGCCATTAAC GTTTTCGCGCTGTTCTGGCTAACCCAGGAAGCGATCCCCCTGCTACCGAAAGGTGCAAGTATCATCACCACTTCGTCAAT CCAGGCATACCAGCCAAGTCCGCATTTACTGGACTATGCGGCTACGAAGGCGGCGATTCTGAACTACAGCCGTGGCTTGG CAAAACAGGTCGCGGAGAAAGGTATTCGGGTGAATATTGTCGCGCCAGGCCCGATCTGGACAGCACTGCAAATTTCCGGC GGACAAACGCAGGATAAGATCCCGCAGTTTGGTCAGCAAACGCCGATGAAACGTGCGGGGCAACCGGCGGAACTGGCCCC TGTATATGTTTATCTGGCAAGTCAGGAGTCGAGCTACGTCACCGCAGAAGTGCACGGCGTGTGCGGCGGCGAGCATTTAG GTTAA
Upstream 100 bases:
>100_bases TGTCGCATAATTCTGAGGTTTAGGGATCTTCCTGGTTCCCTTATCAACGCATCGAGAACGTCTACCCTTAAAGGACGTTG AACCTGAAGGGAGAAAAACG
Downstream 100 bases:
>100_bases AAAAATGCCCGGTTGTGAAAAGCAACCGGGCATCATTGTGAATTCACTCTTACCTGATGTGGCGAAAACGCCTTATCCGC CTACAAACGCATGAAGATTC
Product: oxidoreductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 294; Mature: 293
Protein sequence:
>294_residues MSHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPVPDCGEKTYVGSGRLKDRKALVTGGDSGIGRAAAIAYAREGADVAISY LPVEEEDAQDVKKIIEECGRKAVLLPGDLSDEKFARSLVHEAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAIN VFALFWLTQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISG GQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG
Sequences:
>Translated_294_residues MSHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPVPDCGEKTYVGSGRLKDRKALVTGGDSGIGRAAAIAYAREGADVAISY LPVEEEDAQDVKKIIEECGRKAVLLPGDLSDEKFARSLVHEAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAIN VFALFWLTQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISG GQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG >Mature_293_residues SHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPVPDCGEKTYVGSGRLKDRKALVTGGDSGIGRAAAIAYAREGADVAISYL PVEEEDAQDVKKIIEECGRKAVLLPGDLSDEKFARSLVHEAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAINV FALFWLTQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISGG QTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family
Homologues:
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=32.1285140562249, Blast_Score=111, Evalue=1e-24, Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=30.1204819277108, Blast_Score=95, Evalue=8e-20, Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=30.3846153846154, Blast_Score=93, Evalue=3e-19, Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=26.984126984127, Blast_Score=83, Evalue=4e-16, Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=26.7175572519084, Blast_Score=83, Evalue=4e-16, Organism=Homo sapiens, GI40254992, Length=250, Percent_Identity=29.2, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI59889578, Length=198, Percent_Identity=29.7979797979798, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=32.4742268041237, Blast_Score=80, Evalue=3e-15, Organism=Homo sapiens, GI10190704, Length=253, Percent_Identity=28.8537549407115, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=31.7204301075269, Blast_Score=73, Evalue=4e-13, Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=28.4584980237154, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI66933014, Length=262, Percent_Identity=28.6259541984733, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI32455239, Length=185, Percent_Identity=26.4864864864865, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI5031765, Length=185, Percent_Identity=26.4864864864865, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI210032110, Length=187, Percent_Identity=26.2032085561497, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI109715829, Length=249, Percent_Identity=28.1124497991968, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1789378, Length=294, Percent_Identity=100, Blast_Score=599, Evalue=1e-173, Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=35.3658536585366, Blast_Score=132, Evalue=2e-32, Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=31.3008130081301, Blast_Score=108, Evalue=6e-25, Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=32.3886639676113, Blast_Score=106, Evalue=2e-24, Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=28.9795918367347, Blast_Score=98, Evalue=5e-22, Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=28.8461538461538, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=30.0813008130081, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=27.710843373494, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1786812, Length=264, Percent_Identity=28.4090909090909, Blast_Score=87, Evalue=2e-18, Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=26.6129032258064, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=26.8292682926829, Blast_Score=83, Evalue=3e-17, Organism=Escherichia coli, GI1787526, Length=240, Percent_Identity=32.5, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1786701, Length=213, Percent_Identity=28.169014084507, Blast_Score=67, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=31.5985130111524, Blast_Score=100, Evalue=6e-22, Organism=Caenorhabditis elegans, GI17562904, Length=251, Percent_Identity=30.2788844621514, Blast_Score=100, Evalue=7e-22, Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=29.2682926829268, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17560676, Length=260, Percent_Identity=28.4615384615385, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=30.3149606299213, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=28.8973384030418, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=30.6818181818182, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17560150, Length=270, Percent_Identity=29.6296296296296, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17551412, Length=281, Percent_Identity=29.1814946619217, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=29.6992481203008, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=31.4606741573034, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=30.7407407407407, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17563726, Length=248, Percent_Identity=30.6451612903226, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=32.4528301886792, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=25.3968253968254, Blast_Score=89, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17538480, Length=252, Percent_Identity=28.1746031746032, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI25147288, Length=256, Percent_Identity=30.46875, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=28.6792452830189, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=31.8181818181818, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17544670, Length=258, Percent_Identity=27.5193798449612, Blast_Score=84, Evalue=9e-17, Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=29.6992481203008, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17508651, Length=252, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17555706, Length=263, Percent_Identity=30.0380228136882, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=29.2592592592593, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=29.811320754717, Blast_Score=78, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17564282, Length=196, Percent_Identity=30.6122448979592, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17538182, Length=247, Percent_Identity=29.9595141700405, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=27.4900398406374, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17536651, Length=264, Percent_Identity=27.6515151515151, Blast_Score=72, Evalue=5e-13, Organism=Saccharomyces cerevisiae, GI6323882, Length=246, Percent_Identity=24.7967479674797, Blast_Score=72, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6324126, Length=258, Percent_Identity=28.2945736434109, Blast_Score=64, Evalue=2e-11, Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=31.3253012048193, Blast_Score=110, Evalue=9e-25, Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=29.8804780876494, Blast_Score=107, Evalue=9e-24, Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=30.6772908366534, Blast_Score=99, Evalue=4e-21, Organism=Drosophila melanogaster, GI21355319, Length=244, Percent_Identity=31.1475409836066, Blast_Score=99, Evalue=4e-21, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=29.4820717131474, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=29.3650793650794, Blast_Score=87, Evalue=2e-17, Organism=Drosophila melanogaster, GI17737361, Length=268, Percent_Identity=27.6119402985075, Blast_Score=85, Evalue=7e-17, Organism=Drosophila melanogaster, GI24644337, Length=118, Percent_Identity=34.7457627118644, Blast_Score=75, Evalue=7e-14, Organism=Drosophila melanogaster, GI24643142, Length=236, Percent_Identity=29.2372881355932, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI24584748, Length=209, Percent_Identity=28.7081339712919, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI161076933, Length=209, Percent_Identity=28.7081339712919, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24665243, Length=197, Percent_Identity=26.9035532994924, Blast_Score=65, Evalue=7e-11, Organism=Drosophila melanogaster, GI21357673, Length=198, Percent_Identity=26.2626262626263, Blast_Score=65, Evalue=8e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): YGHA_ECO57 (P0AG85)
Other databases:
- EMBL: AE005174 - EMBL: BA000007 - PIR: G85959 - PIR: G91114 - RefSeq: NP_289580.1 - RefSeq: NP_311914.1 - ProteinModelPortal: P0AG85 - SMR: P0AG85 - MINT: MINT-1264896 - PRIDE: P0AG85 - EnsemblBacteria: EBESCT00000029013 - EnsemblBacteria: EBESCT00000056444 - GeneID: 916290 - GeneID: 961274 - GenomeReviews: AE005174_GR - GenomeReviews: BA000007_GR - KEGG: ece:Z4356 - KEGG: ecs:ECs3887 - GeneTree: EBGT00050000009180 - HOGENOM: HBG750976 - OMA: PQEKIPQ - ProtClustDB: PRK07985 - BioCyc: ECOL83334:ECS3887-MONOMER - GO: GO:0005488 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 - Gene3D: G3DSA:3.40.50.720 - PANTHER: PTHR19410 - PRINTS: PR00081 - PRINTS: PR00080
Pfam domain/function: PF00106 adh_short
EC number: 1.-.-.- [C]
Molecular weight: Translated: 31488; Mature: 31357
Theoretical pI: Translated: 6.79; Mature: 6.79
Prosite motif: PS00061 ADH_SHORT
Important sites: ACT_SITE 199-199 BINDING 186-186
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 1.0 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPVPDCGEKTYVGSGRLKDRKALVTGGDSG CCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEECCCCCCCCEEEEECCCCC IGRAAAIAYAREGADVAISYLPVEEEDAQDVKKIIEECGRKAVLLPGDLSDEKFARSLVH CCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHH EAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAINVFALFWLTQEAIPLLPKGAS HHHHHHCCHHEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE IITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISG EEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECC GQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG CCCHHHHHHHCCCCCHHHCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCC >Mature Secondary Structure SHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPVPDCGEKTYVGSGRLKDRKALVTGGDSG CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEECCCCCCCCEEEEECCCCC IGRAAAIAYAREGADVAISYLPVEEEDAQDVKKIIEECGRKAVLLPGDLSDEKFARSLVH CCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHH EAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAINVFALFWLTQEAIPLLPKGAS HHHHHHCCHHEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE IITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISG EEEECCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECC GQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG CCCHHHHHHHCCCCCHHHCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796