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The map label for this gene is rseB

Identifier: 157162050

GI number: 157162050

Start: 2746134

End: 2747090

Strand: Reverse

Name: rseB

Synonym: EcHS_A2726

Alternate gene names: 157162050

Gene position: 2747090-2746134 (Counterclockwise)

Preceding gene: 157162051

Following gene: 157162049

Centisome position: 59.16

GC content: 50.78

Gene sequence:

>957_bases
ATGAAGCAACTTTGGTTTGCCATGTCATTAGTGACAGGTAGCCTGTTATTCTCTGCTAACGCCTCGGCCACTCCCGCGTC
CGGGGCGTTATTACAGCAGATGAACCTGGCCAGTCAGTCACTGAATTACGAGCTGTCATTCATCAGCATCAATAAACAGG
GTGTTGAGTCTCTGCGTTATCGACATGCACGCCTCGATAACCGTCCTCTTGCACAATTGTTGCAAATGGATGGCCCGCGC
CGGGAAGTGGTACAGCGCGGCAATGAAATCAGCTATTTTGAACCGGGACTTGAACCGTTCACGCTTAATGGCGATTACAT
TGTTGATTCTCTGCCATCGCTTATCTATACCGATTTCAAACGCCTTTCTCCTTACTACGACTTTATCTCCGTCGGGCGCA
CGCGTATTGCTGATCGTCTTTGCGAAGTCATTCGCGTGGTTGCCCGAGATGGTACACGCTACAGCTACATCGTGTGGATG
GACACCGAATCGAAATTACCGATGCGGGTTGATCTCCTTGATCGCGATGGTGAAACGCTGGAACAATTTCGCGTGATTGC
TTTTAACGTCAATCAGGATATCAGCAGCAGTATGCAGACGCTGGCGAAGGCAAATTTGCCGCCGTTGCTTTCTGTTCCTG
TAGGTGAAAAAGCTAAATTCAGCTGGACGCCAACCTGGTTGCCACAGGGTTTTAGCGAAGTTTCCAGTAGTCGACGTCCG
CTACCGACGATGGACAACATGCCTATCGAATCACGTCTCTATTCCGACGGATTATTCAGCTTCTCGGTAAACGTTAACCG
CGCTACGCCATCGAGCACCGATCAGATGTTGCGCACCGGACGCAGAACCGTCAGTACAAGCGTACGTGATAACGCCGAAA
TCACCATTGTCGGTGAACTGCCGCCGCAAACGGCGAAACGCATTGCCGAGAATATTAAGTTCGGGGCAGCGCAATGA

Upstream 100 bases:

>100_bases
GCCGACTCCACTCTGAACAGCTTCAGTTTGAGCAGGCGCAAACCCAGCAAGCCGCTGTACAGGTGCCAGGAATTCAAACT
TTAGGAACGCAATCGCAGTA

Downstream 100 bases:

>100_bases
TCAAAGAGTGGGCTACCGTCGTCTCCTGGCAAAACGGGCAGGCGCTGGTCAGTTGTGATGTTAAAGCTTCATGCAGCAGC
TGCGCTTCACGCGCCGGTTG

Product: periplasmic negative regulator of sigmaE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MKQLWFAMSLVTGSLLFSANASATPASGALLQQMNLASQSLNYELSFISINKQGVESLRYRHARLDNRPLAQLLQMDGPR
REVVQRGNEISYFEPGLEPFTLNGDYIVDSLPSLIYTDFKRLSPYYDFISVGRTRIADRLCEVIRVVARDGTRYSYIVWM
DTESKLPMRVDLLDRDGETLEQFRVIAFNVNQDISSSMQTLAKANLPPLLSVPVGEKAKFSWTPTWLPQGFSEVSSSRRP
LPTMDNMPIESRLYSDGLFSFSVNVNRATPSSTDQMLRTGRRTVSTSVRDNAEITIVGELPPQTAKRIAENIKFGAAQ

Sequences:

>Translated_318_residues
MKQLWFAMSLVTGSLLFSANASATPASGALLQQMNLASQSLNYELSFISINKQGVESLRYRHARLDNRPLAQLLQMDGPR
REVVQRGNEISYFEPGLEPFTLNGDYIVDSLPSLIYTDFKRLSPYYDFISVGRTRIADRLCEVIRVVARDGTRYSYIVWM
DTESKLPMRVDLLDRDGETLEQFRVIAFNVNQDISSSMQTLAKANLPPLLSVPVGEKAKFSWTPTWLPQGFSEVSSSRRP
LPTMDNMPIESRLYSDGLFSFSVNVNRATPSSTDQMLRTGRRTVSTSVRDNAEITIVGELPPQTAKRIAENIKFGAAQ
>Mature_318_residues
MKQLWFAMSLVTGSLLFSANASATPASGALLQQMNLASQSLNYELSFISINKQGVESLRYRHARLDNRPLAQLLQMDGPR
REVVQRGNEISYFEPGLEPFTLNGDYIVDSLPSLIYTDFKRLSPYYDFISVGRTRIADRLCEVIRVVARDGTRYSYIVWM
DTESKLPMRVDLLDRDGETLEQFRVIAFNVNQDISSSMQTLAKANLPPLLSVPVGEKAKFSWTPTWLPQGFSEVSSSRRP
LPTMDNMPIESRLYSDGLFSFSVNVNRATPSSTDQMLRTGRRTVSTSVRDNAEITIVGELPPQTAKRIAENIKFGAAQ

Specific function: Seems to modulate the activity of rpoE (sigma-E)

COG id: COG3026

COG function: function code T; Negative regulator of sigma E activity

Gene ontology:

Cell location: Periplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rseB family

Homologues:

Organism=Escherichia coli, GI1788924, Length=318, Percent_Identity=100, Blast_Score=650, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSEB_ECO57 (P0AFY0)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   C85903
- PIR:   E91058
- RefSeq:   NP_289129.1
- RefSeq:   NP_311464.1
- ProteinModelPortal:   P0AFY0
- SMR:   P0AFY0
- EnsemblBacteria:   EBESCT00000029162
- EnsemblBacteria:   EBESCT00000058993
- GeneID:   914893
- GeneID:   957951
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z3853
- KEGG:   ecs:ECs3437
- GeneTree:   EBGT00050000011592
- HOGENOM:   HBG391417
- OMA:   FIEHDQP
- ProtClustDB:   PRK09455
- BioCyc:   ECOL83334:ECS3437-MONOMER
- InterPro:   IPR005588

Pfam domain/function: PF03888 MucB_RseB

EC number: NA

Molecular weight: Translated: 35750; Mature: 35750

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLWFAMSLVTGSLLFSANASATPASGALLQQMNLASQSLNYELSFISINKQGVESLRY
CCHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECHHHHHHHHH
RHARLDNRPLAQLLQMDGPRREVVQRGNEISYFEPGLEPFTLNGDYIVDSLPSLIYTDFK
HHHHCCCCHHHHHHHCCCCHHHHHHCCCCCCEECCCCCEEEECCCHHHHHHHHHHHHHHH
RLSPYYDFISVGRTRIADRLCEVIRVVARDGTRYSYIVWMDTESKLPMRVDLLDRDGETL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCEEEEEECCCCHHH
EQFRVIAFNVNQDISSSMQTLAKANLPPLLSVPVGEKAKFSWTPTWLPQGFSEVSSSRRP
HHEEEEEEECCHHHHHHHHHHHHCCCCCEEECCCCCCCEECCCCCCCCCCHHHHHHCCCC
LPTMDNMPIESRLYSDGLFSFSVNVNRATPSSTDQMLRTGRRTVSTSVRDNAEITIVGEL
CCCCCCCCHHHHHHCCCEEEEEEEECCCCCCHHHHHHHCCCHHHCCCCCCCCEEEEEECC
PPQTAKRIAENIKFGAAQ
CHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKQLWFAMSLVTGSLLFSANASATPASGALLQQMNLASQSLNYELSFISINKQGVESLRY
CCHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECHHHHHHHHH
RHARLDNRPLAQLLQMDGPRREVVQRGNEISYFEPGLEPFTLNGDYIVDSLPSLIYTDFK
HHHHCCCCHHHHHHHCCCCHHHHHHCCCCCCEECCCCCEEEECCCHHHHHHHHHHHHHHH
RLSPYYDFISVGRTRIADRLCEVIRVVARDGTRYSYIVWMDTESKLPMRVDLLDRDGETL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCEEEEEECCCCHHH
EQFRVIAFNVNQDISSSMQTLAKANLPPLLSVPVGEKAKFSWTPTWLPQGFSEVSSSRRP
HHEEEEEEECCHHHHHHHHHHHHCCCCCEEECCCCCCCEECCCCCCCCCCHHHHHHCCCC
LPTMDNMPIESRLYSDGLFSFSVNVNRATPSSTDQMLRTGRRTVSTSVRDNAEITIVGEL
CCCCCCCCHHHHHHCCCEEEEEEEECCCCCCHHHHHHHCCCHHHCCCCCCCCEEEEEECC
PPQTAKRIAENIKFGAAQ
CHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796