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The map label for this gene is eutG [H]

Identifier: 157161912

GI number: 157161912

Start: 2590231

End: 2591418

Strand: Reverse

Name: eutG [H]

Synonym: EcHS_A2582

Alternate gene names: 157161912

Gene position: 2591418-2590231 (Counterclockwise)

Preceding gene: 157161913

Following gene: 157161911

Centisome position: 55.81

GC content: 59.09

Gene sequence:

>1188_bases
ATGCAAAATGAATTGCAGACCGCGCTCTTTCAGGCGTTCGATACCCTGAATCTGCAACGGGTAAAAACATTTAGCGTTCC
ACCGGTGACGCTTTGCGGTCCGGGCGCGGTGAGCAGTTGCGGGCAGCAAGCGCAAACGCGTGGGCTGAAACATCTGTTCG
TGATGGCAGACAGCTTTTTGCATCAGGCGGGGATGACCGCCGGGCTGACGCGCAGCCTGGCTGTTAAAGGCATCGCCATG
ACGCTCTGGCCATGTCCGGTGGGCGAACCGTGCATTACCGACGTGTGTGCAGCCGTGGCGCAGTTGCGTGAGTCAGGCTG
TGATGGGGTGATCGCATTTGGCGGCGGCTCGGTGCTGGATGCGGCGAAAGCCGTGGCGTTGCTGGTGACGAACCCCGATA
GCACGCTGGCAGAGATGTCAGAAACCAGCGTTCTGCAACCGCGCTTGCCGCTGATTGCCATTCCAACGACCGCCGGAACC
GGCTCTGAAACCACCAATGTAACGGTGATTATCGACGCGGTGAGCGGGCGCAAGCAGGTGTTAGCCCATGCCTCGCTGAT
GCCGGATGTGGCGATCCTCGACGCCGCATTGACCGAAGGTGTGCCGTCGCATGTCACGGCGATGACCGGCATTGATGCGT
TAACCCATGCCATTGAAGCATACAGCGCCCTGAACGCTACACCGTTTACCGACAGCCTGGCGATTGGTGCCATTGCGATG
ATTGGCAAATCGCTGCCGAAAGCGGTGGGCTACGGTCACGACCTTGCCGCGCGCGAGAGCATGTTACTGGCTTCATGTAT
GGCGGGAATGGCGTTTTCCAGTGCGGGTCTTGGGTTGTGCCACGCGATGGCGCATCAGCCGGGCGCGGCGCTGCATATTC
CGCACGGTCTCGCGAACGCCATGTTGCTGCCAACGGTGATGGAATTTAACCGGATGGTTTGTCGTGAACGCTTTAGTCAG
ATTGGTCGGGCACTGCGAACTAAAAAATCCGACGATCGTGACGCTATTAACGCGGTAAGTGAGCTGATTGCGGAAGTTGG
GATTGGTAAACGACTGGGCGATGTTGGTGCGACATCTGCGCATTACGGCGCATGGGCGCAGGCCGCGCTGGAAGATATTT
GTCTGCGCAGTAACCCGCGTACCGCCAGCCTGGAGCAGATTGTCGGCCTGTACGCAGCGGCGCAATAA

Upstream 100 bases:

>100_bases
AAACAATTCCCGGCGTTACAGGTGCATTTACCGCAGCACAGTTTGTTTATGACCCCGCTGGCGATCGCCAGTAGTGGGCG
AGAGAAAGCGGAGGGGCTAT

Downstream 100 bases:

>100_bases
ATGCCGGATGCGACGCTTGCCGCATCTTATCCAGCCTACGGGATTGCACATGTAGGGCGGATAAGGCGTTCACGCCGCAT
CCGCCAGTGGCGCGGTGCAA

Product: ethanolamine utilization protein EutG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MQNELQTALFQAFDTLNLQRVKTFSVPPVTLCGPGAVSSCGQQAQTRGLKHLFVMADSFLHQAGMTAGLTRSLAVKGIAM
TLWPCPVGEPCITDVCAAVAQLRESGCDGVIAFGGGSVLDAAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGT
GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAALTEGVPSHVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
IGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGLANAMLLPTVMEFNRMVCRERFSQ
IGRALRTKKSDDRDAINAVSELIAEVGIGKRLGDVGATSAHYGAWAQAALEDICLRSNPRTASLEQIVGLYAAAQ

Sequences:

>Translated_395_residues
MQNELQTALFQAFDTLNLQRVKTFSVPPVTLCGPGAVSSCGQQAQTRGLKHLFVMADSFLHQAGMTAGLTRSLAVKGIAM
TLWPCPVGEPCITDVCAAVAQLRESGCDGVIAFGGGSVLDAAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGT
GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAALTEGVPSHVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
IGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGLANAMLLPTVMEFNRMVCRERFSQ
IGRALRTKKSDDRDAINAVSELIAEVGIGKRLGDVGATSAHYGAWAQAALEDICLRSNPRTASLEQIVGLYAAAQ
>Mature_395_residues
MQNELQTALFQAFDTLNLQRVKTFSVPPVTLCGPGAVSSCGQQAQTRGLKHLFVMADSFLHQAGMTAGLTRSLAVKGIAM
TLWPCPVGEPCITDVCAAVAQLRESGCDGVIAFGGGSVLDAAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGT
GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAALTEGVPSHVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
IGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGLANAMLLPTVMEFNRMVCRERFSQ
IGRALRTKKSDDRDAINAVSELIAEVGIGKRLGDVGATSAHYGAWAQAALEDICLRSNPRTASLEQIVGLYAAAQ

Specific function: May act on the acetaldehyde produced from the degradation of ethanolamine [H]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=407, Percent_Identity=26.5356265356265, Blast_Score=113, Evalue=4e-25,
Organism=Escherichia coli, GI87082107, Length=395, Percent_Identity=99.2405063291139, Blast_Score=798, Evalue=0.0,
Organism=Escherichia coli, GI48994951, Length=378, Percent_Identity=37.037037037037, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1789163, Length=372, Percent_Identity=40.0537634408602, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1787493, Length=383, Percent_Identity=32.3759791122715, Blast_Score=185, Evalue=4e-48,
Organism=Escherichia coli, GI1789386, Length=284, Percent_Identity=26.4084507042254, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17537053, Length=323, Percent_Identity=27.5541795665635, Blast_Score=123, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321181, Length=380, Percent_Identity=33.6842105263158, Blast_Score=216, Evalue=7e-57,
Organism=Drosophila melanogaster, GI24657991, Length=404, Percent_Identity=27.7227722772277, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: NA

Molecular weight: Translated: 40956; Mature: 40956

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNELQTALFQAFDTLNLQRVKTFSVPPVTLCGPGAVSSCGQQAQTRGLKHLFVMADSFL
CCHHHHHHHHHHHHHCCHHHEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
HQAGMTAGLTRSLAVKGIAMTLWPCPVGEPCITDVCAAVAQLRESGCDGVIAFGGGSVLD
HHHCCHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHH
AAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGTGSETTNVTVIIDAVSGRKQV
HHHEEEEEEECCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCHHHH
LAHASLMPDVAILDAALTEGVPSHVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
HHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
IGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGLANA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCHHHHH
MLLPTVMEFNRMVCRERFSQIGRALRTKKSDDRDAINAVSELIAEVGIGKRLGDVGATSA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCC
HYGAWAQAALEDICLRSNPRTASLEQIVGLYAAAQ
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MQNELQTALFQAFDTLNLQRVKTFSVPPVTLCGPGAVSSCGQQAQTRGLKHLFVMADSFL
CCHHHHHHHHHHHHHCCHHHEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
HQAGMTAGLTRSLAVKGIAMTLWPCPVGEPCITDVCAAVAQLRESGCDGVIAFGGGSVLD
HHHCCHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHH
AAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGTGSETTNVTVIIDAVSGRKQV
HHHEEEEEEECCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCHHHH
LAHASLMPDVAILDAALTEGVPSHVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
HHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
IGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGLANA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEECCCHHHHH
MLLPTVMEFNRMVCRERFSQIGRALRTKKSDDRDAINAVSELIAEVGIGKRLGDVGATSA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCC
HYGAWAQAALEDICLRSNPRTASLEQIVGLYAAAQ
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]