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The map label for this gene is dedA

Identifier: 157161805

GI number: 157161805

Start: 2475653

End: 2476312

Strand: Reverse

Name: dedA

Synonym: EcHS_A2468

Alternate gene names: 157161805

Gene position: 2476312-2475653 (Counterclockwise)

Preceding gene: 157161806

Following gene: 157161804

Centisome position: 53.33

GC content: 48.94

Gene sequence:

>660_bases
ATGGACCTGATTTATTTCCTCATCGATTTTATCCTGCACATTGACGTGCATCTGGCAGAGCTGGTCGCGGAGTACGGCGT
CTGGGTTTATGCCATTTTGTTCTTAATTTTGTTCTGTGAAACCGGTCTGGTGGTAACGCCGTTTTTACCGGGTGATTCAT
TGCTGTTTGTTGCCGGAGCGTTGGCATCACTGGAAACCAACGATCTCAACGTCCATATGATGGTGGTGCTGATGCTGATC
GCCGCGATTGTGGGTGACGCGGTCAATTACACTATCGGGCGGTTGTTCGGTGAAAAGTTGTTCAGTAATCCCAATTCGAA
AATTTTCCGTCGCAGTTATCTCGACAAAACCCATCAGTTTTATGAGAAACATGGCGGCAAAACGATTATTCTCGCCCGTT
TTGTGCCGATCGTCAGAACGTTCGCCCCGTTTGTTGCGGGAATGGGCCACATGTCGTACCGTCATTTCGCCGCTTATAAC
GTGATCGGCGCACTGTTGTGGGTACTGCTTTTTACCTACGCAGGCTATTTCTTCGGTACAATCCCGATGGTTCAGGATAA
CCTTAAGCTGCTGATCGTCGGGATTATTGTGGTTTCTATTTTGCCGGGCGTCATCGAAATAATCCGTCACAAACGCGCTG
CGGCACGCGCCGCAAAATAA

Upstream 100 bases:

>100_bases
CTATTTCTGGCGGACTAACGAGAATAATGCTCGGAACATTTCAGGCTGTAGCCAACGTAGTTACAGCCTGAAAGATGACG
AGTACAAGGCATAGGCAAAT

Downstream 100 bases:

>100_bases
AAAGTAACTCCGCGGTTCGACCACTTTTTTATCCAAAGTTTCGGGCTGTTATGTTTTAATGTGCAACATTCATGGTCTGT
TGGGGGCAAAAATGGCATTA

Product: hypothetical protein

Products: NA

Alternate protein names: Protein DSG-1

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MDLIYFLIDFILHIDVHLAELVAEYGVWVYAILFLILFCETGLVVTPFLPGDSLLFVAGALASLETNDLNVHMMVVLMLI
AAIVGDAVNYTIGRLFGEKLFSNPNSKIFRRSYLDKTHQFYEKHGGKTIILARFVPIVRTFAPFVAGMGHMSYRHFAAYN
VIGALLWVLLFTYAGYFFGTIPMVQDNLKLLIVGIIVVSILPGVIEIIRHKRAAARAAK

Sequences:

>Translated_219_residues
MDLIYFLIDFILHIDVHLAELVAEYGVWVYAILFLILFCETGLVVTPFLPGDSLLFVAGALASLETNDLNVHMMVVLMLI
AAIVGDAVNYTIGRLFGEKLFSNPNSKIFRRSYLDKTHQFYEKHGGKTIILARFVPIVRTFAPFVAGMGHMSYRHFAAYN
VIGALLWVLLFTYAGYFFGTIPMVQDNLKLLIVGIIVVSILPGVIEIIRHKRAAARAAK
>Mature_219_residues
MDLIYFLIDFILHIDVHLAELVAEYGVWVYAILFLILFCETGLVVTPFLPGDSLLFVAGALASLETNDLNVHMMVVLMLI
AAIVGDAVNYTIGRLFGEKLFSNPNSKIFRRSYLDKTHQFYEKHGGKTIILARFVPIVRTFAPFVAGMGHMSYRHFAAYN
VIGALLWVLLFTYAGYFFGTIPMVQDNLKLLIVGIIVVSILPGVIEIIRHKRAAARAAK

Specific function: Unknown

COG id: COG0586

COG function: function code S; Uncharacterized membrane-associated protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dedA family

Homologues:

Organism=Escherichia coli, GI1788656, Length=219, Percent_Identity=100, Blast_Score=440, Evalue=1e-125,
Organism=Escherichia coli, GI1789481, Length=154, Percent_Identity=34.4155844155844, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1789384, Length=192, Percent_Identity=29.6875, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEDA_ECO57 (P0ABP7)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   A98029
- RefSeq:   NP_288891.1
- RefSeq:   NP_311228.1
- ProteinModelPortal:   P0ABP7
- EnsemblBacteria:   EBESCT00000026117
- EnsemblBacteria:   EBESCT00000059834
- GeneID:   917121
- GeneID:   957482
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z3579
- KEGG:   ecs:ECs3201
- GeneTree:   EBGT00050000009773
- HOGENOM:   HBG657460
- OMA:   YARHGGK
- ProtClustDB:   PRK10847
- BioCyc:   ECOL83334:ECS3201-MONOMER
- InterPro:   IPR015414

Pfam domain/function: PF09335 SNARE_assoc

EC number: NA

Molecular weight: Translated: 24511; Mature: 24511

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x16038864)-; HASH(0x1564b880)-; HASH(0x16180210)-; HASH(0x16021280)-; HASH(0x1639a948)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLIYFLIDFILHIDVHLAELVAEYGVWVYAILFLILFCETGLVVTPFLPGDSLLFVAGA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHH
LASLETNDLNVHMMVVLMLIAAIVGDAVNYTIGRLFGEKLFSNPNSKIFRRSYLDKTHQF
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
YEKHGGKTIILARFVPIVRTFAPFVAGMGHMSYRHFAAYNVIGALLWVLLFTYAGYFFGT
HHHCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IPMVQDNLKLLIVGIIVVSILPGVIEIIRHKRAAARAAK
CHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MDLIYFLIDFILHIDVHLAELVAEYGVWVYAILFLILFCETGLVVTPFLPGDSLLFVAGA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHH
LASLETNDLNVHMMVVLMLIAAIVGDAVNYTIGRLFGEKLFSNPNSKIFRRSYLDKTHQF
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
YEKHGGKTIILARFVPIVRTFAPFVAGMGHMSYRHFAAYNVIGALLWVLLFTYAGYFFGT
HHHCCCCEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IPMVQDNLKLLIVGIIVVSILPGVIEIIRHKRAAARAAK
CHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796