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The map label for this gene is ubiX

Identifier: 157161799

GI number: 157161799

Start: 2469628

End: 2470197

Strand: Reverse

Name: ubiX

Synonym: EcHS_A2462

Alternate gene names: 157161799

Gene position: 2470197-2469628 (Counterclockwise)

Preceding gene: 157161800

Following gene: 157161798

Centisome position: 53.2

GC content: 53.16

Gene sequence:

>570_bases
ATGAAACGACTCATTGTAGGCATCAGCGGTGCCAGCGGCGCGATTTATGGCGTGCGCTTATTACAGGTTCTGCGCGATGT
CACAGATATCGAAACGCATCTGGTGATGAGCCAGGCAGCGCGCCAGACCTTATCCCTCGAAACGGATTTTTCTCTGCGCG
AAGTGCAGGCATTAGCCGATGTCACGCACGATGCGCGCGATATTGCCGCCAGCATCTCTTCCGGTTCTTTCCAGACGCTG
GGGATGGTGATTTTACCCTGTTCAATCAAAACCCTTTCCGGCATTGTCCATAGCTATACTGATGGCTTACTGACCCGTGC
GGCAGATGTGGTGCTGAAAGAGCGTCGCCCGTTGGTGCTCTGCGTGCGTGAAACACCATTGCACTTAGGCCATCTGCGTT
TAATGACTCAGGCGGCAGAAATCGGTGCGGTGATTATGCCTCCCGTTCCGGCGTTTTATCATCGCCCGCAATCCCTTGAT
GATGTGATAAATCAGACGGTTAATCGTGTTCTTGACCAGTTTGCGATAACCCTTCCTGAAGATCTCTTTGCCCGCTGGCA
GGGCGCATAA

Upstream 100 bases:

>100_bases
GGATGATGCCTTCGCTGAGGGTGCCGGTCTGGCACCCTGACTTGCAACTCCCGCCGAAATCCTGCAAAGTCTGCCTGCAA
GTCTGACAGGGCAACTATTT

Downstream 100 bases:

>100_bases
CTCCGCTGTTGCCCTGTTTCAGGGCAATTTTGCAACCGCGATCAAATCCTCGACATTTTGTTTCTGCCATTCAATCGAAA
CGCTGCGATTCAACCGCTAT

Product: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase

Products: NA

Alternate protein names: Polyprenyl p-hydroxybenzoate decarboxylase

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MKRLIVGISGASGAIYGVRLLQVLRDVTDIETHLVMSQAARQTLSLETDFSLREVQALADVTHDARDIAASISSGSFQTL
GMVILPCSIKTLSGIVHSYTDGLLTRAADVVLKERRPLVLCVRETPLHLGHLRLMTQAAEIGAVIMPPVPAFYHRPQSLD
DVINQTVNRVLDQFAITLPEDLFARWQGA

Sequences:

>Translated_189_residues
MKRLIVGISGASGAIYGVRLLQVLRDVTDIETHLVMSQAARQTLSLETDFSLREVQALADVTHDARDIAASISSGSFQTL
GMVILPCSIKTLSGIVHSYTDGLLTRAADVVLKERRPLVLCVRETPLHLGHLRLMTQAAEIGAVIMPPVPAFYHRPQSLD
DVINQTVNRVLDQFAITLPEDLFARWQGA
>Mature_189_residues
MKRLIVGISGASGAIYGVRLLQVLRDVTDIETHLVMSQAARQTLSLETDFSLREVQALADVTHDARDIAASISSGSFQTL
GMVILPCSIKTLSGIVHSYTDGLLTRAADVVLKERRPLVLCVRETPLHLGHLRLMTQAAEIGAVIMPPVPAFYHRPQSLD
DVINQTVNRVLDQFAITLPEDLFARWQGA

Specific function: Unknown

COG id: COG0163

COG function: function code H; 3-polyprenyl-4-hydroxybenzoate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polyprenyl P-hydroxybenzoate / phenylacrylic acid decarboxylases family

Homologues:

Organism=Escherichia coli, GI1788650, Length=189, Percent_Identity=100, Blast_Score=382, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6320746, Length=187, Percent_Identity=50.2673796791444, Blast_Score=189, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIX_ECO57 (P0AG04)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   C91028
- PIR:   D85872
- RefSeq:   NP_288885.1
- RefSeq:   NP_311222.1
- ProteinModelPortal:   P0AG04
- SMR:   P0AG04
- EnsemblBacteria:   EBESCT00000028200
- EnsemblBacteria:   EBESCT00000055355
- GeneID:   916903
- GeneID:   959527
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z3573
- KEGG:   ecs:ECs3195
- GeneTree:   EBGT00050000011085
- HOGENOM:   HBG297290
- OMA:   FTRWQGA
- ProtClustDB:   PRK06029
- BioCyc:   ECOL83334:ECS3195-MONOMER
- InterPro:   IPR003382
- InterPro:   IPR004507
- Gene3D:   G3DSA:3.40.50.1950
- TIGRFAMs:   TIGR00421

Pfam domain/function: PF02441 Flavoprotein; SSF52507 Flavoprotein

EC number: 4.1.1.-

Molecular weight: Translated: 20695; Mature: 20695

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: BINDING 37-37 BINDING 123-123

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLIVGISGASGAIYGVRLLQVLRDVTDIETHLVMSQAARQTLSLETDFSLREVQALAD
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
VTHDARDIAASISSGSFQTLGMVILPCSIKTLSGIVHSYTDGLLTRAADVVLKERRPLVL
HHHHHHHHHHHHCCCCCHHHCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
CVRETPLHLGHLRLMTQAAEIGAVIMPPVPAFYHRPQSLDDVINQTVNRVLDQFAITLPE
EEECCCCHHHHHHHHHHHHHCCEEECCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCH
DLFARWQGA
HHHHHCCCC
>Mature Secondary Structure
MKRLIVGISGASGAIYGVRLLQVLRDVTDIETHLVMSQAARQTLSLETDFSLREVQALAD
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
VTHDARDIAASISSGSFQTLGMVILPCSIKTLSGIVHSYTDGLLTRAADVVLKERRPLVL
HHHHHHHHHHHHCCCCCHHHCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
CVRETPLHLGHLRLMTQAAEIGAVIMPPVPAFYHRPQSLDDVINQTVNRVLDQFAITLPE
EEECCCCHHHHHHHHHHHHHCCEEECCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCH
DLFARWQGA
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Carbon Lyases; Carboxy-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796