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The map label for this gene is glpC [H]

Identifier: 157161727

GI number: 157161727

Start: 2396503

End: 2397693

Strand: Direct

Name: glpC [H]

Synonym: EcHS_A2384

Alternate gene names: 157161727

Gene position: 2396503-2397693 (Clockwise)

Preceding gene: 157161726

Following gene: 157161728

Centisome position: 51.61

GC content: 53.57

Gene sequence:

>1191_bases
ATGAACGACACCAGCTTCGAAAACTGCATTAAGTGCACCGTCTGCACCACCGCCTGCCCGGTGAGCCGGGTGAATCCCGG
TTATCCAGGGCCAAAACAAGCCGGGCCGGATGGCGAGCGTCTGCGTTTGAAAGATGGCGCACTGTATGACGAGGCGCTGA
AATATTGCATCAACTGCAAACGTTGTGAAGTCGCCTGCCCGTCCGATGTGAAGATTGGCGATATTATCCAGCGCGCGCGG
GCAAAATATGACACCACGCGCCCGTCGCTGCGTAATTTTGTGTTGAGTCATACCGACCTGATGGGTAGCGTTTCCACGCC
GTTCGCACCAATCGTCAACACCGCTACCTCGCTGAAACCGGTGCGGCAGCTGCTTGATGCGGCGTTAAAAATCGATCATC
GTCGCACGCTACCGAAATACTCCTTCGGCACGTTCCGTCGCTGGTATCGCAGCATAGCGGCTCAGCAAGCACAATATAAA
GACCAGGTCGCTTTCTTTCACGGATGCTTCGTTAACTACAACCATCCGCAGTTAGGTAAAGATTTAATTAAAGTGCTCAA
CGCAATGGGTACCGGTGTACAACTGCTCAGCAAAGAAAAATGCTGCGGCGTACCGCTAATCGCCAACGGCTTTACCGATA
AAGCACGCAAACAGGCAATTACGAATGTAGAGTCGATCCGCGAAGCTGTGGGAGTAAAAGGCATTCCGGTGATTGCCACC
TCCTCAACCTGTACATTTGCCCTGCGCGACGAATACCCGGAAGTGCTGAATGTCGACAACAAAGGCTTGCGCGATCATAT
CGAACTGGCAACCCGCTGGCTGTGGCGCAAGCTGGACGAAGGCAAAACGTTACCGCTGAAACCGCTGCCGCTGAAAGTGG
TTTATCACACTCCGTGCCATATGGAAAAAATGGGCTGGACGCTCTACACCCTGGAGCTGTTGCGTAAAATCCCGGGGCTT
GAGTTAACGGTGCTGGATTCCCAGTGCTGCGGTATTGCGGGTACTTACGGTTTCAAAAAAGAGAACTACCCCACCTCACA
AGCCATCGGCGCACCACTGTTCCGCCAGATAGAAGAAAGCGGCGCAGATCTGGTGGTCACCGACTGCGAAACCTGTAAAT
GGCAGATTGAGATGTCCACAAGTCTTCGCTGCGAACATCCGATTACGCTACTGGCCCAGGCGCTGGCTTAA

Upstream 100 bases:

>100_bases
GCGGATTTGATCCCATCGCCCAGGGATGCGGCGGCGGTGTTTGTGCCGTCAGTGCTTTACATGCCGCTCAACAGATTGCC
CAACGCGCAGGAGGCCAACA

Downstream 100 bases:

>100_bases
ACTCCTTTCTGATGCCCGGTAAGCATGTGGTTACCGGGCATTTTTGCGTACACGATTCCGTGCCCAATGTATGCGTTGCA
ACGCAGTGAAAATTCCTCTG

Product: sn-glycerol-3-phosphate dehydrogenase subunit C

Products: glycerone phosphate; reduced acceptor

Alternate protein names: G-3-P dehydrogenase [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLKDGALYDEALKYCINCKRCEVACPSDVKIGDIIQRAR
AKYDTTRPSLRNFVLSHTDLMGSVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSIAAQQAQYK
DQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQAITNVESIREAVGVKGIPVIAT
SSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWRKLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRKIPGL
ELTVLDSQCCGIAGTYGFKKENYPTSQAIGAPLFRQIEESGADLVVTDCETCKWQIEMSTSLRCEHPITLLAQALA

Sequences:

>Translated_396_residues
MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLKDGALYDEALKYCINCKRCEVACPSDVKIGDIIQRAR
AKYDTTRPSLRNFVLSHTDLMGSVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSIAAQQAQYK
DQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQAITNVESIREAVGVKGIPVIAT
SSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWRKLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRKIPGL
ELTVLDSQCCGIAGTYGFKKENYPTSQAIGAPLFRQIEESGADLVVTDCETCKWQIEMSTSLRCEHPITLLAQALA
>Mature_396_residues
MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLKDGALYDEALKYCINCKRCEVACPSDVKIGDIIQRAR
AKYDTTRPSLRNFVLSHTDLMGSVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSIAAQQAQYK
DQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQAITNVESIREAVGVKGIPVIAT
SSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWRKLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRKIPGL
ELTVLDSQCCGIAGTYGFKKENYPTSQAIGAPLFRQIEESGADLVVTDCETCKWQIEMSTSLRCEHPITLLAQALA

Specific function: Electron transfer protein; may also function as the membrane anchor for the glpAB dimer [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=Loosely bound to the cytoplasmic membrane often occurring in vesicles associated with fumarate reductase [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1788576, Length=396, Percent_Identity=99.4949494949495, Blast_Score=823, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR004017
- InterPro:   IPR012285
- InterPro:   IPR017753
- InterPro:   IPR009051 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: 1.1.99.5

Molecular weight: Translated: 44137; Mature: 44137

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLKDGALYDEALKYCINCK
CCCCCHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCC
RCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFVLSHTDLMGSVSTPFAPIVNTATSLKP
CCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
VRQLLDAALKIDHRRTLPKYSFGTFRRWYRSIAAQQAQYKDQVAFFHGCFVNYNHPQLGK
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHH
DLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQAITNVESIREAVGVKGIPVIAT
HHHHHHHHHCCCHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEE
SSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWRKLDEGKTLPLKPLPLKVVYHTPCH
CCCEEEEECCCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCC
MEKMGWTLYTLELLRKIPGLELTVLDSQCCGIAGTYGFKKENYPTSQAIGAPLFRQIEES
HHHHCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHC
GADLVVTDCETCKWQIEMSTSLRCEHPITLLAQALA
CCCEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHC
>Mature Secondary Structure
MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLKDGALYDEALKYCINCK
CCCCCHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCC
RCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFVLSHTDLMGSVSTPFAPIVNTATSLKP
CCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
VRQLLDAALKIDHRRTLPKYSFGTFRRWYRSIAAQQAQYKDQVAFFHGCFVNYNHPQLGK
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHH
DLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQAITNVESIREAVGVKGIPVIAT
HHHHHHHHHCCCHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEE
SSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWRKLDEGKTLPLKPLPLKVVYHTPCH
CCCEEEEECCCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCC
MEKMGWTLYTLELLRKIPGLELTVLDSQCCGIAGTYGFKKENYPTSQAIGAPLFRQIEES
HHHHCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHC
GADLVVTDCETCKWQIEMSTSLRCEHPITLLAQALA
CCCEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: sn-glycerol 3-phosphate; acceptor

Specific reaction: sn-glycerol 3-phosphate + acceptor = glycerone phosphate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]