Click here to switch to the map view.

The map label for this gene is ompC [H]

Identifier: 157161697

GI number: 157161697

Start: 2352627

End: 2353733

Strand: Reverse

Name: ompC [H]

Synonym: EcHS_A2354

Alternate gene names: 157161697

Gene position: 2353733-2352627 (Counterclockwise)

Preceding gene: 157161698

Following gene: 157161696

Centisome position: 50.69

GC content: 50.95

Gene sequence:

>1107_bases
ATGAAAGTTAAAGTACTGTCCCTCCTGGTCCCAGCTCTGCTGGTAGCAGGCGCAGCAAACGCTGCTGAAGTTTACAACAA
AGACGGCAACAAATTAGATCTGTACGGTAAAGTAGACGGCCTGCACTATTTCTCTGACAACAAGTCAGAAGACGGCGACC
AGACCTATGTACGTCTTGGTTTCAAAGGCGAAACTCAGGTTACTGACCAGCTGACCGGTTACGGCCAGTGGGAATATCAG
ATCCAGGGCAATACCTCTGAAGACAACAAAGAAAACTCCTGGACCCGTGTGGCATTCGCAGGTCTGAAATTCCAGGATGT
AGGTTCTTTCGACTACGGTCGTAACTACGGCGTTGTTTACGACGTAACTTCCTGGACCGACGTACTGCCAGAATTCGGTG
GCGACACCTACGGTTCTGACAACTTCATGCAGCAGCGTGGTAACGGCTTCGCGACCTACCGTAACACCGACTTCTTCGGT
CTGGTTGACGGTCTGAACTTTGCTGTTCAGTACCAGGGCAAAAACGGCAGCGTAAGCGGCGAAGGCATGACCAACAACGG
TCGTGGCGCTCTGCGTCAGAACGGCGACGGTGTCGGCGGTTCTATCACTTATGATTACGAAGGCTTCGGTATCGGTGCTG
CAGTTTCCAGCTCCAAACGTACTGATGCTCAGAACACCGCTGCTTACATCGGTAACGGCGACCGTGCTGAAACCTACACT
GGTGGTCTGAAATACGACGCTAACAACATCTACCTGGCTGCTCAGTACACCCAGACCTACAACGCAACTCGCGTAGGTTC
CCTGGGTTGGGCGAACAAAGCACAGAACTTCGAAGCTGTTGCTCAGTACCAGTTCGACTTCGGTCTGCGTCCGTCTGTAG
CATACCTGCAGTCTAAAGGTAAAAACCTGGGTGTCGTTGCTGGTCGTAACTACGACGACGAAGATATCCTGAAATATGTT
GATGTTGGTGCGACCTACTACTTCAACAAAAACATGTCCACCTACGTTGACTACAAAATCAACCTGCTGGACGACAACCA
GTTCACTCGTGACGCTGGCATCAACACTGATAACATCGTAGCTCTGGGTCTGGTTTACCAGTTCTAA

Upstream 100 bases:

>100_bases
ATTTTTGGGGAGAATGGACTTGCCGACTGATTAATGAGGGTTAATCAGTATGCAGTGGCATAAAAAAGCAAATAAAGGCA
TATAACAGAGGGTTAATAAC

Downstream 100 bases:

>100_bases
TCTCGATGGATATCGAACAAAGGGCCTGCGGGCCCTTTTTTCATTGTTTTCAGCGTACAAACACAGTTTTTTGGTGTACT
CTTGCGACCGTTCGCATGAG

Product: outer membrane porin protein C

Products: NA

Alternate protein names: Outer membrane protein 1B; Porin ompC [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDNKSEDGDQTYVRLGFKGETQVTDQLTGYGQWEYQ
IQGNTSEDNKENSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFG
LVDGLNFAVQYQGKNGSVSGEGMTNNGRGALRQNGDGVGGSITYDYEGFGIGAAVSSSKRTDAQNTAAYIGNGDRAETYT
GGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSVAYLQSKGKNLGVVAGRNYDDEDILKYV
DVGATYYFNKNMSTYVDYKINLLDDNQFTRDAGINTDNIVALGLVYQF

Sequences:

>Translated_368_residues
MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDNKSEDGDQTYVRLGFKGETQVTDQLTGYGQWEYQ
IQGNTSEDNKENSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFG
LVDGLNFAVQYQGKNGSVSGEGMTNNGRGALRQNGDGVGGSITYDYEGFGIGAAVSSSKRTDAQNTAAYIGNGDRAETYT
GGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSVAYLQSKGKNLGVVAGRNYDDEDILKYV
DVGATYYFNKNMSTYVDYKINLLDDNQFTRDAGINTDNIVALGLVYQF
>Mature_368_residues
MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDNKSEDGDQTYVRLGFKGETQVTDQLTGYGQWEYQ
IQGNTSEDNKENSWTRVAFAGLKFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFG
LVDGLNFAVQYQGKNGSVSGEGMTNNGRGALRQNGDGVGGSITYDYEGFGIGAAVSSSKRTDAQNTAAYIGNGDRAETYT
GGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSVAYLQSKGKNLGVVAGRNYDDEDILKYV
DVGATYYFNKNMSTYVDYKINLLDDNQFTRDAGINTDNIVALGLVYQF

Specific function: Forms passive diffusion pores which allow small molecular weight hydrophilic materials across the outer membrane [H]

COG id: COG3203

COG function: function code M; Outer membrane protein (porin)

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Gram-negative porin family [H]

Homologues:

Organism=Escherichia coli, GI1788544, Length=372, Percent_Identity=93.5483870967742, Blast_Score=681, Evalue=0.0,
Organism=Escherichia coli, GI1787641, Length=380, Percent_Identity=67.6315789473684, Blast_Score=451, Evalue=1e-128,
Organism=Escherichia coli, GI1786436, Length=372, Percent_Identity=56.989247311828, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1787160, Length=381, Percent_Identity=59.5800524934383, Blast_Score=407, Evalue=1e-115,

Paralogues:

None

Copy number: 6020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 19068 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001897
- InterPro:   IPR013793
- InterPro:   IPR001702 [H]

Pfam domain/function: PF00267 Porin_1 [H]

EC number: NA

Molecular weight: Translated: 40424; Mature: 40424

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS00576 GRAM_NEG_PORIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDNKSEDGDQTYVRLG
CEEEHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEECCEEEECCCCCCCCCCEEEEEE
FKGETQVTDQLTGYGQWEYQIQGNTSEDNKENSWTRVAFAGLKFQDVGSFDYGRNYGVVY
CCCCCEEHHHHCCCCEEEEEECCCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCCEEE
DVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFGLVDGLNFAVQYQGKNGSVSG
ECCCHHHHHHHHCCCCCCCCHHHHHCCCEEEEEECCCEEEEECCCEEEEEEECCCCCCCC
EGMTNNGRGALRQNGDGVGGSITYDYEGFGIGAAVSSSKRTDAQNTAAYIGNGDRAETYT
CCCCCCCCCCEECCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCEEEECCCCCCCEEE
GGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSVAYLQSKG
CCEEECCCCEEEEEEEEECCCCEECCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHCC
KNLGVVAGRNYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRDAGINTDNIV
CEEEEEECCCCCHHHHHHHHHCCEEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCEE
ALGLVYQF
EEEEEECC
>Mature Secondary Structure
MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDNKSEDGDQTYVRLG
CEEEHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEECCEEEECCCCCCCCCCEEEEEE
FKGETQVTDQLTGYGQWEYQIQGNTSEDNKENSWTRVAFAGLKFQDVGSFDYGRNYGVVY
CCCCCEEHHHHCCCCEEEEEECCCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCCEEE
DVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFGLVDGLNFAVQYQGKNGSVSG
ECCCHHHHHHHHCCCCCCCCHHHHHCCCEEEEEECCCEEEEECCCEEEEEEECCCCCCCC
EGMTNNGRGALRQNGDGVGGSITYDYEGFGIGAAVSSSKRTDAQNTAAYIGNGDRAETYT
CCCCCCCCCCEECCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCEEEECCCCCCCEEE
GGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSVAYLQSKG
CCEEECCCCEEEEEEEEECCCCEECCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHCC
KNLGVVAGRNYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRDAGINTDNIV
CEEEEEECCCCCHHHHHHHHHCCEEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCEE
ALGLVYQF
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]