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The map label for this gene is ccmD

Identifier: 157161679

GI number: 157161679

Start: 2336356

End: 2336565

Strand: Reverse

Name: ccmD

Synonym: EcHS_A2336

Alternate gene names: 157161679

Gene position: 2336565-2336356 (Counterclockwise)

Preceding gene: 157161680

Following gene: 157161678

Centisome position: 50.32

GC content: 56.67

Gene sequence:

>210_bases
ATGACCCCTGCATTTGCTTCCTGGAATGAATTTTTCGCAATGGGCGGTTACGCCTTTTTTGTCTGGCTGGCGGTGGTGAT
GACCGTTATTCCGCTGGTGGTTTTGGTCGTGCACTCGGTGATGCAACATCGCGCAATTCTGCGTGGTGTGGCGCAACAGC
GGGCGCGTGAGGCGCGTTTACGTGCTGCGCAACAGCAGGAGGCTGCATGA

Upstream 100 bases:

>100_bases
TGTCTGCCACGCTGACGCTGATGCGGATGCGTAATTTGATTTTGCTGATGGAAAAACGCCGTCCGTGGGTGAGTGAACTG
ATACTGAAAAGAGGCCGTAA

Downstream 100 bases:

>100_bases
ATATTCGCCGTAAAAACCGCTTGTGGATTGCCTGTGCCGTGTTGGCAGGGCTGGCGCTGACTATCGGTCTGGTGCTATAT
GCGCTGCGCTCGAATATCGA

Product: heme exporter protein D

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmD

Number of amino acids: Translated: 69; Mature: 68

Protein sequence:

>69_residues
MTPAFASWNEFFAMGGYAFFVWLAVVMTVIPLVVLVVHSVMQHRAILRGVAQQRAREARLRAAQQQEAA

Sequences:

>Translated_69_residues
MTPAFASWNEFFAMGGYAFFVWLAVVMTVIPLVVLVVHSVMQHRAILRGVAQQRAREARLRAAQQQEAA
>Mature_68_residues
TPAFASWNEFFAMGGYAFFVWLAVVMTVIPLVVLVVHSVMQHRAILRGVAQQRAREARLRAAQQQEAA

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes

COG id: COG3114

COG function: function code U; Heme exporter protein D

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmD/CycX/HelD family

Homologues:

Organism=Escherichia coli, GI1788526, Length=69, Percent_Identity=100, Blast_Score=137, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCMD_ECO57 (P0ABM7)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   A85859
- PIR:   G91014
- RefSeq:   NP_288778.1
- RefSeq:   NP_311114.1
- ProteinModelPortal:   P0ABM7
- EnsemblBacteria:   EBESCT00000026903
- EnsemblBacteria:   EBESCT00000055260
- GeneID:   916793
- GeneID:   957172
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z3455
- KEGG:   ecs:ECs3087
- GeneTree:   EBGT00050000011398
- HOGENOM:   HBG757581
- OMA:   QFDSISE
- ProtClustDB:   CLSK880330
- BioCyc:   ECOL83334:ECS3087-MONOMER
- GO:   GO:0006810
- InterPro:   IPR007078
- TIGRFAMs:   TIGR03141

Pfam domain/function: PF04995 CcmD

EC number: NA

Molecular weight: Translated: 7745; Mature: 7614

Theoretical pI: Translated: 11.81; Mature: 11.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x16055bf8)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPAFASWNEFFAMGGYAFFVWLAVVMTVIPLVVLVVHSVMQHRAILRGVAQQRAREARL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAAQQQEAA
HHHHHHCCH
>Mature Secondary Structure 
TPAFASWNEFFAMGGYAFFVWLAVVMTVIPLVVLVVHSVMQHRAILRGVAQQRAREARL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAAQQQEAA
HHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796