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The map label for this gene is sanA

Identifier: 157161624

GI number: 157161624

Start: 2275277

End: 2275996

Strand: Direct

Name: sanA

Synonym: EcHS_A2278

Alternate gene names: 157161624

Gene position: 2275277-2275996 (Clockwise)

Preceding gene: 157161623

Following gene: 157161625

Centisome position: 49.0

GC content: 47.78

Gene sequence:

>720_bases
ATGTTAAAGCGCGTGTTCCTCAGCCTGTTAGTCCTGATCGGCTTGCTGCTGTTGACTGTGCTCGGCCTCGATCGCTGGAT
GAGCTGGAAAACCGCGCCTTATATCTACGACGAATTGCAGGATCTCCCCTACCGCCAGGTCGGTGTGGTGCTCGGAACAG
CAAAATATTATCGTACTGGCGTAATTAATCAGTATTATCGCTACCGCATTCAAGGAGCGATTAATGCCTATAACAGCGGT
AAGGTAAATTATCTATTACTGAGCGGCGATAACGCATTGCAAAGTTATAATGAGCCGATGACCATGCGCAAAGATTTAAT
CGCTGCTGGTGTCGACCCATCAGATATTGTTCTCGATTACGCAGGCTTTCGTACGCTGGATTCCATCGTGCGTACACGCA
AAGTTTTCGATACTAATGATTTCATTATTATCACCCAACGTTTCCACTGTGAGCGAGCATTATTTATTGCGCTGCATATG
GGGATTCAGGCTCAGTGTTATGCCGTACCGTCACCGAAAGATATGCTGTCAGTACGTATTCGTGAATTTGCCGCCCGTTT
CGGTGCGCTGGCTGACCTTTATATTTTTAAACGTGAACCGCGTTTTTTAGGGCCGCTGGTCCCTATTCCGGCTATGCACC
AGGTACCGGAAGATGCGCAGGGGTATCCCGCCGTCACACCCGAACAGTTACTTGAATTACAAAAGAAACAAGGAAAGTAG

Upstream 100 bases:

>100_bases
TCCTGGTGTCGAAAATCCCGGCAAACAGTTTGCCGTTTCTTGCGCAAAACCAGCGGGTAAAGTAGCCTGATGGAAATTTT
CCTTAGATCGAGTCTCCTGC

Downstream 100 bases:

>100_bases
TTATGGATGTACAGCAGTTTTTTGTCGTTGCCGTTTTTTTCCTTATCCCGATATTTTGTTTCCGCGAAGCATGGAAAGGC
TGGCGCGCAGGCGCGATTGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MLKRVFLSLLVLIGLLLLTVLGLDRWMSWKTAPYIYDELQDLPYRQVGVVLGTAKYYRTGVINQYYRYRIQGAINAYNSG
KVNYLLLSGDNALQSYNEPMTMRKDLIAAGVDPSDIVLDYAGFRTLDSIVRTRKVFDTNDFIIITQRFHCERALFIALHM
GIQAQCYAVPSPKDMLSVRIREFAARFGALADLYIFKREPRFLGPLVPIPAMHQVPEDAQGYPAVTPEQLLELQKKQGK

Sequences:

>Translated_239_residues
MLKRVFLSLLVLIGLLLLTVLGLDRWMSWKTAPYIYDELQDLPYRQVGVVLGTAKYYRTGVINQYYRYRIQGAINAYNSG
KVNYLLLSGDNALQSYNEPMTMRKDLIAAGVDPSDIVLDYAGFRTLDSIVRTRKVFDTNDFIIITQRFHCERALFIALHM
GIQAQCYAVPSPKDMLSVRIREFAARFGALADLYIFKREPRFLGPLVPIPAMHQVPEDAQGYPAVTPEQLLELQKKQGK
>Mature_239_residues
MLKRVFLSLLVLIGLLLLTVLGLDRWMSWKTAPYIYDELQDLPYRQVGVVLGTAKYYRTGVINQYYRYRIQGAINAYNSG
KVNYLLLSGDNALQSYNEPMTMRKDLIAAGVDPSDIVLDYAGFRTLDSIVRTRKVFDTNDFIIITQRFHCERALFIALHM
GIQAQCYAVPSPKDMLSVRIREFAARFGALADLYIFKREPRFLGPLVPIPAMHQVPEDAQGYPAVTPEQLLELQKKQGK

Specific function: Participates in the barrier function of the cell envelope

COG id: COG2949

COG function: function code S; Uncharacterized membrane protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788466, Length=239, Percent_Identity=100, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI1789468, Length=231, Percent_Identity=38.5281385281385, Blast_Score=139, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SANA_ECO57 (P0AFY4)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   D91008
- PIR:   F85852
- RefSeq:   NP_288727.1
- RefSeq:   NP_311063.1
- ProteinModelPortal:   P0AFY4
- PRIDE:   P0AFY4
- EnsemblBacteria:   EBESCT00000024063
- EnsemblBacteria:   EBESCT00000055243
- GeneID:   916740
- GeneID:   957084
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z3399
- KEGG:   ecs:ECs3036
- GeneTree:   EBGT00050000010348
- HOGENOM:   HBG670642
- OMA:   DFTIITQ
- ProtClustDB:   PRK10834
- BioCyc:   ECOL83334:ECS3036-MONOMER
- InterPro:   IPR003848
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620

Pfam domain/function: PF02698 DUF218

EC number: NA

Molecular weight: Translated: 27287; Mature: 27287

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x15e47a74)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRVFLSLLVLIGLLLLTVLGLDRWMSWKTAPYIYDELQDLPYRQVGVVLGTAKYYRTG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHCCHHHHHHH
VINQYYRYRIQGAINAYNSGKVNYLLLSGDNALQSYNEPMTMRKDLIAAGVDPSDIVLDY
HHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHCCCCHHHHHHHHHCCCCHHHHEEEH
AGFRTLDSIVRTRKVFDTNDFIIITQRFHCERALFIALHMGIQAQCYAVPSPKDMLSVRI
HHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
REFAARFGALADLYIFKREPRFLGPLVPIPAMHQVPEDAQGYPAVTPEQLLELQKKQGK
HHHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHCCH
>Mature Secondary Structure
MLKRVFLSLLVLIGLLLLTVLGLDRWMSWKTAPYIYDELQDLPYRQVGVVLGTAKYYRTG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHCCHHHHHHH
VINQYYRYRIQGAINAYNSGKVNYLLLSGDNALQSYNEPMTMRKDLIAAGVDPSDIVLDY
HHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHCCCCHHHHHHHHHCCCCHHHHEEEH
AGFRTLDSIVRTRKVFDTNDFIIITQRFHCERALFIALHMGIQAQCYAVPSPKDMLSVRI
HHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
REFAARFGALADLYIFKREPRFLGPLVPIPAMHQVPEDAQGYPAVTPEQLLELQKKQGK
HHHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796