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The map label for this gene is rcsA [H]

Identifier: 157161422

GI number: 157161422

Start: 2043708

End: 2044331

Strand: Direct

Name: rcsA [H]

Synonym: EcHS_A2051

Alternate gene names: 157161422

Gene position: 2043708-2044331 (Clockwise)

Preceding gene: 157161421

Following gene: 157161424

Centisome position: 44.01

GC content: 37.82

Gene sequence:

>624_bases
ATGTCAACGATTATTATGGATTTATGTAGTTACACCCGACTAGGTTTAACCGGGTATCTGTTGAGTAGAGGGGTTAAAAA
AAGAGAAATCAACGACATTGAAACCGTTGATGACCTTGCCATAGCTTGTGATTCACAGCGCCCTTCAGTGGTGTTTATTA
ATGAGGACTGTTTCATCCATGATGCTTCTAACAGTCAGCACATCAAGCACATCATTAATCAACATCCCAATACGTTATTT
ATCGTTTTTATGGCAATTGCCAATGTTCATTTTGATGAATATCTATTGGTCAGAAAAAATTTATTGATCAATTCTAAATC
GATTAAACCGGAATCTCTCGACGATATCCTTGGCGATATTCTGAAAAAAGAGACAACGATAACCTCGTTTTTAAATATGC
CGACGTTATCATTGAGCCGAACCGAATCGAGTATGTTGCGAATGTGGATGGCAGGTCAGGGAACCATTCAAATCTCTGAC
CAAATGAATATCAAAGCCAAGACCGTTTCATCGCATAAAGGTAATATTAAACGTAAGATCAAAACGCATAATAAACAGGT
TATCTACCATGTCGTCCGACTGACGGATAATGTGACTAATGGTATTTTTGTCAACATGCGCTAA

Upstream 100 bases:

>100_bases
CGCGAGAGTGGCGCATTAGGTGACCCATGTTGTTCCGTTTAGTCATGATGAAATATTCAGGTAAGGGGAATTATCGTTAC
GCATTGAGTGAGGGTATGCC

Downstream 100 bases:

>100_bases
CACATTCTGACTGGTGGTTTCCCACCAGTCAGGCTGAATAAGATTACTCTGCTTTCTCCACAAAGATACCGTCCTGATGC
CCTGCTTCATTAAAGAACCA

Product: colanic acid capsular biosynthesis activation protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSTIIMDLCSYTRLGLTGYLLSRGVKKREINDIETVDDLAIACDSQRPSVVFINEDCFIHDASNSQHIKHIINQHPNTLF
IVFMAIANVHFDEYLLVRKNLLINSKSIKPESLDDILGDILKKETTITSFLNMPTLSLSRTESSMLRMWMAGQGTIQISD
QMNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR

Sequences:

>Translated_207_residues
MSTIIMDLCSYTRLGLTGYLLSRGVKKREINDIETVDDLAIACDSQRPSVVFINEDCFIHDASNSQHIKHIINQHPNTLF
IVFMAIANVHFDEYLLVRKNLLINSKSIKPESLDDILGDILKKETTITSFLNMPTLSLSRTESSMLRMWMAGQGTIQISD
QMNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR
>Mature_206_residues
STIIMDLCSYTRLGLTGYLLSRGVKKREINDIETVDDLAIACDSQRPSVVFINEDCFIHDASNSQHIKHIINQHPNTLFI
VFMAIANVHFDEYLLVRKNLLINSKSIKPESLDDILGDILKKETTITSFLNMPTLSLSRTESSMLRMWMAGQGTIQISDQ
MNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR

Specific function: Positive regulator of capsular polysaccharide synthesis. RcsA and rcsB form a complex to promote transcription of the genes for capsule synthesis [H]

COG id: COG2771

COG function: function code K; DNA-binding HTH domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788262, Length=207, Percent_Identity=98.5507246376812, Blast_Score=418, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016032
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE [H]

EC number: NA

Molecular weight: Translated: 23549; Mature: 23418

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIIMDLCSYTRLGLTGYLLSRGVKKREINDIETVDDLAIACDSQRPSVVFINEDCFIH
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHEEECCCCCCEEEEECCEEEE
DASNSQHIKHIINQHPNTLFIVFMAIANVHFDEYLLVRKNLLINSKSIKPESLDDILGDI
ECCCCHHHHHHHHCCCCEEEHHHHHHHHCCHHHHHHHHHHHEECCCCCCCCHHHHHHHHH
LKKETTITSFLNMPTLSLSRTESSMLRMWMAGQGTIQISDQMNIKAKTVSSHKGNIKRKI
HHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCHHHHH
KTHNKQVIYHVVRLTDNVTNGIFVNMR
HHCCHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure 
STIIMDLCSYTRLGLTGYLLSRGVKKREINDIETVDDLAIACDSQRPSVVFINEDCFIH
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHEEECCCCCCEEEEECCEEEE
DASNSQHIKHIINQHPNTLFIVFMAIANVHFDEYLLVRKNLLINSKSIKPESLDDILGDI
ECCCCHHHHHHHHCCCCEEEHHHHHHHHCCHHHHHHHHHHHEECCCCCCCCHHHHHHHHH
LKKETTITSFLNMPTLSLSRTESSMLRMWMAGQGTIQISDQMNIKAKTVSSHKGNIKRKI
HHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCHHHHH
KTHNKQVIYHVVRLTDNVTNGIFVNMR
HHCCHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]