Click here to switch to the map view.

The map label for this gene is fliD [H]

Identifier: 157161395

GI number: 157161395

Start: 2022876

End: 2024291

Strand: Direct

Name: fliD [H]

Synonym: EcHS_A2024

Alternate gene names: 157161395

Gene position: 2022876-2024291 (Clockwise)

Preceding gene: 157161387

Following gene: 157161396

Centisome position: 43.56

GC content: 49.79

Gene sequence:

>1416_bases
ATGGCTAGTATTTCAACGCTTGGGGTTGGGTCGGGGCTGGACTTAAGCAGCATCCTTGACAGTCTGGAGGCGGCAGAAAA
ATCTACCCTGACGCCGATATCAAAACAGCAAAGCTCTTACACCGCGAAACTGAGCGCCTACGGGACGCTGAAAAGTGCAC
TAGAGAGTTTCCAGACAGCCAACACAGCACTGAATAAAGCCGATTTATTTACCGCCACCTCAACCACCAGCAGTTCATCG
GCTTTCAGCGCCACCACCACGGGCAGCGCGATTGCTGGGAAATACACCATTAGCGTTAGCCAACTGGCGCAGGCACAGAC
GCTGACAACAAAAAATAGTCAAAAAGACAGTAAAGCCGCCATCGCCACCAGCGATAGCGTACTGACCATCCAACAAGGCG
GCGGTAAAGATCCGGTCACGATTGATATCAGCGCGGGTAACTCGTCACTTTCCGGCATTCGCGATGCCATTAACAACGCC
AAAGCTGGTGTCAGCGCCAGTATCATCAATGTGGGAAACGGCGAATATCGTCTGTCCATCACCGCTAACGATACGGGCAG
CAATAACGCTATGAAACTTAGCGTCAGCGGCGACAGCGCCCTGGAAAGTTTTATGGGTTACAACGGAACGCCGGGTGATA
GCAGCAATGGCATGATTGAAAGCGTCACCGCGCAAAACGCCAAACTGACAGTCAATAACGTTGAGATTGAAAACAGCAGT
AACACTATCAGCGACTCACTGGAAGATATCACCCTCAACCTGAATGACGTCACCACCGGTAATCAGACACTGACCATCAG
TAAAGACACATCCAAAGCTGAAAATGCGGTTAAAGCGTGGGTGGATGCCTATAACACATTGCAGGATACATTCAGCAGCT
TAACCAAATACACCGCTGTCGATGCCGGAGCTGAAAGTCAGGACTCCAGTAATGGCGCATTACTCGGTGACTCCACACTG
CGTACCATCCAGACTCAGCTTAAAACCTTGCTCGCCAATACTCACAGCAGTTCAAACTATAAAACGCTGGCACAGATTGG
CATTACCAGCGATGCCAGTACCGGCAAGCTGGAAATCGCGACCGACAAACTGCAAACGGCGCTAAAAAATGATGCCGCTG
GTATCGGTGAAATGTTTATAGGTGACGGCAAAAGTACTGGGGTAACCACCGGCATTAGTAACAACCTGACCAGTTGGCTC
TCTTCCACCGGGATAATCCAGGCAGCAAAAGATGGCGTCAGCAAAACGCTGAATAATTTGACCGACCAGTACAACGCAGC
CAGTGAACGTATCGATACCTTAATGACGCGCTATAAAGCCCAGTTCACCCAATTAGATGTGTTAATGAACTCGCTGAACT
CCACTAGTAGCTATCTGACACAGCAGTTCGACACCTCAAATAGCAACTCGAAATAA

Upstream 100 bases:

>100_bases
TTCGTGCCATTAAGGCAAAAAATAAATCGTAAACTTTACCCCGCTTACGCCGATAACCCCGGTATTCGTTCTATACACGT
CGCATGATTAAGGAAACTAT

Downstream 100 bases:

>100_bases
TCTTCAGGAGAGACTATGTACGCGGCAAAAGGCACCCAGGCCTATGCACAAATTGGCGTCGAAAGCGCCGTAATGAGCGC
CAGCCAACAGCAGCTGGTCA

Product: flagellar capping protein

Products: NA

Alternate protein names: HAP2; Filament cap protein [H]

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MASISTLGVGSGLDLSSILDSLEAAEKSTLTPISKQQSSYTAKLSAYGTLKSALESFQTANTALNKADLFTATSTTSSSS
AFSATTTGSAIAGKYTISVSQLAQAQTLTTKNSQKDSKAAIATSDSVLTIQQGGGKDPVTIDISAGNSSLSGIRDAINNA
KAGVSASIINVGNGEYRLSITANDTGSNNAMKLSVSGDSALESFMGYNGTPGDSSNGMIESVTAQNAKLTVNNVEIENSS
NTISDSLEDITLNLNDVTTGNQTLTISKDTSKAENAVKAWVDAYNTLQDTFSSLTKYTAVDAGAESQDSSNGALLGDSTL
RTIQTQLKTLLANTHSSSNYKTLAQIGITSDASTGKLEIATDKLQTALKNDAAGIGEMFIGDGKSTGVTTGISNNLTSWL
SSTGIIQAAKDGVSKTLNNLTDQYNAASERIDTLMTRYKAQFTQLDVLMNSLNSTSSYLTQQFDTSNSNSK

Sequences:

>Translated_471_residues
MASISTLGVGSGLDLSSILDSLEAAEKSTLTPISKQQSSYTAKLSAYGTLKSALESFQTANTALNKADLFTATSTTSSSS
AFSATTTGSAIAGKYTISVSQLAQAQTLTTKNSQKDSKAAIATSDSVLTIQQGGGKDPVTIDISAGNSSLSGIRDAINNA
KAGVSASIINVGNGEYRLSITANDTGSNNAMKLSVSGDSALESFMGYNGTPGDSSNGMIESVTAQNAKLTVNNVEIENSS
NTISDSLEDITLNLNDVTTGNQTLTISKDTSKAENAVKAWVDAYNTLQDTFSSLTKYTAVDAGAESQDSSNGALLGDSTL
RTIQTQLKTLLANTHSSSNYKTLAQIGITSDASTGKLEIATDKLQTALKNDAAGIGEMFIGDGKSTGVTTGISNNLTSWL
SSTGIIQAAKDGVSKTLNNLTDQYNAASERIDTLMTRYKAQFTQLDVLMNSLNSTSSYLTQQFDTSNSNSK
>Mature_470_residues
ASISTLGVGSGLDLSSILDSLEAAEKSTLTPISKQQSSYTAKLSAYGTLKSALESFQTANTALNKADLFTATSTTSSSSA
FSATTTGSAIAGKYTISVSQLAQAQTLTTKNSQKDSKAAIATSDSVLTIQQGGGKDPVTIDISAGNSSLSGIRDAINNAK
AGVSASIINVGNGEYRLSITANDTGSNNAMKLSVSGDSALESFMGYNGTPGDSSNGMIESVTAQNAKLTVNNVEIENSSN
TISDSLEDITLNLNDVTTGNQTLTISKDTSKAENAVKAWVDAYNTLQDTFSSLTKYTAVDAGAESQDSSNGALLGDSTLR
TIQTQLKTLLANTHSSSNYKTLAQIGITSDASTGKLEIATDKLQTALKNDAAGIGEMFIGDGKSTGVTTGISNNLTSWLS
STGIIQAAKDGVSKTLNNLTDQYNAASERIDTLMTRYKAQFTQLDVLMNSLNSTSSYLTQQFDTSNSNSK

Specific function: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the

COG id: COG1345

COG function: function code N; Flagellar capping protein

Gene ontology:

Cell location: Secreted. Bacterial flagellum [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliD family [H]

Homologues:

Organism=Escherichia coli, GI1788233, Length=471, Percent_Identity=78.9808917197452, Blast_Score=666, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010809
- InterPro:   IPR003481 [H]

Pfam domain/function: PF07195 FliD_C; PF02465 FliD_N [H]

EC number: NA

Molecular weight: Translated: 48856; Mature: 48725

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASISTLGVGSGLDLSSILDSLEAAEKSTLTPISKQQSSYTAKLSAYGTLKSALESFQTA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCCCEEEHHHHHHHHHHHHHHHHH
NTALNKADLFTATSTTSSSSAFSATTTGSAIAGKYTISVSQLAQAQTLTTKNSQKDSKAA
HHHCCHHHEEEEECCCCCCCCEEECCCCCEEEEEEEEEHHHHHHHHHHHCCCCCCCCCEE
IATSDSVLTIQQGGGKDPVTIDISAGNSSLSGIRDAINNAKAGVSASIINVGNGEYRLSI
EEECCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEE
TANDTGSNNAMKLSVSGDSALESFMGYNGTPGDSSNGMIESVTAQNAKLTVNNVEIENSS
EECCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEEEEEEECCC
NTISDSLEDITLNLNDVTTGNQTLTISKDTSKAENAVKAWVDAYNTLQDTFSSLTKYTAV
CCHHCCCCEEEEEECEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAGAESQDSSNGALLGDSTLRTIQTQLKTLLANTHSSSNYKTLAQIGITSDASTGKLEIA
CCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEE
TDKLQTALKNDAAGIGEMFIGDGKSTGVTTGISNNLTSWLSSTGIIQAAKDGVSKTLNNL
HHHHHHHHHHCCCCCCHHEECCCCCCCEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
TDQYNAASERIDTLMTRYKAQFTQLDVLMNSLNSTSSYLTQQFDTSNSNSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ASISTLGVGSGLDLSSILDSLEAAEKSTLTPISKQQSSYTAKLSAYGTLKSALESFQTA
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCCCEEEHHHHHHHHHHHHHHHHH
NTALNKADLFTATSTTSSSSAFSATTTGSAIAGKYTISVSQLAQAQTLTTKNSQKDSKAA
HHHCCHHHEEEEECCCCCCCCEEECCCCCEEEEEEEEEHHHHHHHHHHHCCCCCCCCCEE
IATSDSVLTIQQGGGKDPVTIDISAGNSSLSGIRDAINNAKAGVSASIINVGNGEYRLSI
EEECCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEE
TANDTGSNNAMKLSVSGDSALESFMGYNGTPGDSSNGMIESVTAQNAKLTVNNVEIENSS
EECCCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEEEEEEECCC
NTISDSLEDITLNLNDVTTGNQTLTISKDTSKAENAVKAWVDAYNTLQDTFSSLTKYTAV
CCHHCCCCEEEEEECEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAGAESQDSSNGALLGDSTLRTIQTQLKTLLANTHSSSNYKTLAQIGITSDASTGKLEIA
CCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEE
TDKLQTALKNDAAGIGEMFIGDGKSTGVTTGISNNLTSWLSSTGIIQAAKDGVSKTLNNL
HHHHHHHHHHCCCCCCHHEECCCCCCCEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
TDQYNAASERIDTLMTRYKAQFTQLDVLMNSLNSTSSYLTQQFDTSNSNSK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1527488; 9097040; 9278503; 2659972; 6305924 [H]