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The map label for this gene is ydjN

Identifier: 157161189

GI number: 157161189

Start: 1827735

End: 1829126

Strand: Direct

Name: ydjN

Synonym: EcHS_A1810

Alternate gene names: 157161189

Gene position: 1827735-1829126 (Clockwise)

Preceding gene: 157161188

Following gene: 157161192

Centisome position: 39.36

GC content: 52.37

Gene sequence:

>1392_bases
ATGAACTTTCCATTAATTGCGAACATCGTGGTGTTCGTTGTACTGCTGTTTGCGCTGGCTCAGACCCGCCATAAACAGTG
GAGTCTGGCGAAAAAAGTGCTGGTGGGTCTGGTGATGGGTGTGGTTTTTGGCCTTGCCCTGCATACCATTTATGGTTCTG
ACAGCCAGGTACTTAAAGATTCTGTACAGTGGTTTAACATCGTTGGTAACGGCTATGTTCAACTGCTGCAAATGATCGTT
ATGCCGTTAGTCTTCGCCTCTATTCTGAGCGCGGTTGCCCGTCTGCATAACGCATCTCAGTTAGGCAAAATCAGTTTTCT
GACCATCGGTACGCTTTTGTTTACCACGCTGATTGCGGCGCTGGTCGGTGTGCTGGTCACCAACCTGTTTGGTTTGACGG
CTGAAGGTCTGGTTCAGGGTGGTGCAGAAACTGCACGTCTGAACGCCATTGAAAGTAACTATGTTGGTAAAGTCTCTGAT
CTGAGCGTTCCGCAGCTGGTCTTGTCCTTTATCCCGAAAAACCCGTTTGCCGATCTTACCGGAGCCAATCCGACGTCAAT
TATCAGCGTGGTAATTTTTGCCGCATTCCTCGGCGTAGCTGCATTGAAACTGCTGAAGGATGATGCTCCGAAAGGTGAAC
GCGTCTTAGCCGCTATCGATACCCTACAAAGCTGGGTGATGAAACTGGTTCGCCTGGTCATGCAGTTGACCCCTTACGGC
GTTCTGGCTCTAATGACCAAAGTGGTTGCAGGTTCTAACTTGCAAGACATCATCAAACTGGGAAGTTTCGTTGTCGCGTC
CTACCTCGGTCTGCTGATTATGTTTGCAGTGCATGGCATTCTGCTGGGCATTAATGGCGTGAGTCCGCTGAAGTACTTCC
GTAAGGTATGGCCTGTGCTGACGTTTGCCTTTACCAGCCGTTCCAGTGCTGCGTCTATCCCACTGAATGTGGAAGCACAA
ACGCGTCGTCTGGGCGTTCCTGAATCCATCGCCAGTTTCGCCGCCTCTTTCGGTGCAACCATTGGTCAGAACGGCTGCGC
CGGTTTGTATCCGGCAATGCTGGCGGTGATGGTTGCGCCTACGGTTGGCATTAACCCGCTGGACCCGATGTGGATTGCGA
CGCTGGTCGGTATTGTTACCGTTAGTTCCGCAGGCGTTGCCGGTGTCGGTGGTGGTGCAACTTTCGCCGCACTGATTGTA
CTGCCTGCGATGGGCCTGCCAGTAACCCTGGTGGCGCTGTTAATCTCCGTTGAACCGCTTATCGACATGGGCCGTACGGC
GTTAAACGTTAGTGGCTCGATGACAGCTGGCACGCTGACCAGCCAGTGGCTGAAGCAAACCGATAAAGCCATTCTGGATA
GCGAAGACGACGCCGAACTGGCACACCATTAA

Upstream 100 bases:

>100_bases
TTCCATTTGAATATAAGAGCCAGCTCACAGTTCTGTTAATCTTGCGCCAACACTATGACTGCTACGCAGTGATAGAAATA
ATAAGATCAGGAGAACGGGG

Downstream 100 bases:

>100_bases
TTCTTATGCTGGCAACGGTCCGTTTTGTATAGGGGCCGTTGCCTTACTTTTTAAATGTTCCATCGCGGCGATGCATACTG
ACTCATATTTAAACAGATCG

Product: sodium/dicarboxylate symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MNFPLIANIVVFVVLLFALAQTRHKQWSLAKKVLVGLVMGVVFGLALHTIYGSDSQVLKDSVQWFNIVGNGYVQLLQMIV
MPLVFASILSAVARLHNASQLGKISFLTIGTLLFTTLIAALVGVLVTNLFGLTAEGLVQGGAETARLNAIESNYVGKVSD
LSVPQLVLSFIPKNPFADLTGANPTSIISVVIFAAFLGVAALKLLKDDAPKGERVLAAIDTLQSWVMKLVRLVMQLTPYG
VLALMTKVVAGSNLQDIIKLGSFVVASYLGLLIMFAVHGILLGINGVSPLKYFRKVWPVLTFAFTSRSSAASIPLNVEAQ
TRRLGVPESIASFAASFGATIGQNGCAGLYPAMLAVMVAPTVGINPLDPMWIATLVGIVTVSSAGVAGVGGGATFAALIV
LPAMGLPVTLVALLISVEPLIDMGRTALNVSGSMTAGTLTSQWLKQTDKAILDSEDDAELAHH

Sequences:

>Translated_463_residues
MNFPLIANIVVFVVLLFALAQTRHKQWSLAKKVLVGLVMGVVFGLALHTIYGSDSQVLKDSVQWFNIVGNGYVQLLQMIV
MPLVFASILSAVARLHNASQLGKISFLTIGTLLFTTLIAALVGVLVTNLFGLTAEGLVQGGAETARLNAIESNYVGKVSD
LSVPQLVLSFIPKNPFADLTGANPTSIISVVIFAAFLGVAALKLLKDDAPKGERVLAAIDTLQSWVMKLVRLVMQLTPYG
VLALMTKVVAGSNLQDIIKLGSFVVASYLGLLIMFAVHGILLGINGVSPLKYFRKVWPVLTFAFTSRSSAASIPLNVEAQ
TRRLGVPESIASFAASFGATIGQNGCAGLYPAMLAVMVAPTVGINPLDPMWIATLVGIVTVSSAGVAGVGGGATFAALIV
LPAMGLPVTLVALLISVEPLIDMGRTALNVSGSMTAGTLTSQWLKQTDKAILDSEDDAELAHH
>Mature_463_residues
MNFPLIANIVVFVVLLFALAQTRHKQWSLAKKVLVGLVMGVVFGLALHTIYGSDSQVLKDSVQWFNIVGNGYVQLLQMIV
MPLVFASILSAVARLHNASQLGKISFLTIGTLLFTTLIAALVGVLVTNLFGLTAEGLVQGGAETARLNAIESNYVGKVSD
LSVPQLVLSFIPKNPFADLTGANPTSIISVVIFAAFLGVAALKLLKDDAPKGERVLAAIDTLQSWVMKLVRLVMQLTPYG
VLALMTKVVAGSNLQDIIKLGSFVVASYLGLLIMFAVHGILLGINGVSPLKYFRKVWPVLTFAFTSRSSAASIPLNVEAQ
TRRLGVPESIASFAASFGATIGQNGCAGLYPAMLAVMVAPTVGINPLDPMWIATLVGIVTVSSAGVAGVGGGATFAALIV
LPAMGLPVTLVALLISVEPLIDMGRTALNVSGSMTAGTLTSQWLKQTDKAILDSEDDAELAHH

Specific function: Unknown

COG id: COG1823

COG function: function code R; Predicted Na+/dicarboxylate symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family

Homologues:

Organism=Homo sapiens, GI223468564, Length=287, Percent_Identity=30.6620209059233, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI223468566, Length=287, Percent_Identity=30.6620209059233, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI5032093, Length=286, Percent_Identity=30.4195804195804, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI194239697, Length=468, Percent_Identity=23.5042735042735, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI21314632, Length=435, Percent_Identity=26.8965517241379, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI40254478, Length=512, Percent_Identity=25.5859375, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI66773030, Length=374, Percent_Identity=27.5401069518717, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI169790839, Length=467, Percent_Identity=25.6959314775161, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI4827012, Length=304, Percent_Identity=28.2894736842105, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1788024, Length=463, Percent_Identity=100, Blast_Score=914, Evalue=0.0,
Organism=Escherichia coli, GI1790514, Length=440, Percent_Identity=26.8181818181818, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789947, Length=436, Percent_Identity=22.7064220183486, Blast_Score=113, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71983099, Length=438, Percent_Identity=26.027397260274, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71983106, Length=438, Percent_Identity=26.027397260274, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI193206654, Length=482, Percent_Identity=25.103734439834, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI193206505, Length=481, Percent_Identity=24.3243243243243, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17541374, Length=445, Percent_Identity=24.7191011235955, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71996953, Length=467, Percent_Identity=25.0535331905782, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17537407, Length=449, Percent_Identity=24.4988864142539, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24583025, Length=462, Percent_Identity=24.8917748917749, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17137668, Length=462, Percent_Identity=24.8917748917749, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24583023, Length=462, Percent_Identity=24.8917748917749, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YDJN_ECOLI (P77529)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   A64932
- RefSeq:   AP_002348.1
- RefSeq:   NP_416243.1
- ProteinModelPortal:   P77529
- SMR:   P77529
- DIP:   DIP-11776N
- STRING:   P77529
- EnsemblBacteria:   EBESCT00000001204
- EnsemblBacteria:   EBESCT00000015446
- GeneID:   946238
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW1718
- KEGG:   eco:b1729
- EchoBASE:   EB3746
- EcoGene:   EG13990
- eggNOG:   COG1823
- GeneTree:   EBGT00050000009806
- HOGENOM:   HBG739804
- OMA:   AWVMRLV
- ProtClustDB:   CLSK880176
- BioCyc:   EcoCyc:G6934-MONOMER
- Genevestigator:   P77529
- InterPro:   IPR001991
- PANTHER:   PTHR11958
- PRINTS:   PR00173

Pfam domain/function: PF00375 SDF

EC number: NA

Molecular weight: Translated: 48662; Mature: 48662

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS00713 NA_DICARBOXYL_SYMP_1; PS00714 NA_DICARBOXYL_SYMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x15225c2c)-; HASH(0x152ef030)-; HASH(0x140d7014)-; HASH(0x152e2c24)-; HASH(0x14dd8af0)-; HASH(0x1530e00c)-; HASH(0x119d98c4)-; HASH(0x12c657c4)-; HASH(0x152ef03c)-; HASH(0x152fbeac)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCHHEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCH
>Mature Secondary Structure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HHCCCHHEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503