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The map label for this gene is dmsC2

Identifier: 157161049

GI number: 157161049

Start: 1685744

End: 1686598

Strand: Direct

Name: dmsC2

Synonym: EcHS_A1663

Alternate gene names: 157161049

Gene position: 1685744-1686598 (Clockwise)

Preceding gene: 157161048

Following gene: 157161050

Centisome position: 36.3

GC content: 52.63

Gene sequence:

>855_bases
ATGGGAAATGGATGGCATGAGTGGCCACTGGTTATCTTTACCGTATTGGGTCAATGCGTAGTAGGCGCGCTGATTGTTAG
CGGAATTGGCTGGTTCGCCGCCAAAAATGACGCAGACCGTCAGCGTATTGTCCGTGGCATGTTTTTCCTCTGGCTGTTGA
TGGGCGTCGGGTTTATTGCCTCTGTCATGCACCTGGGATCGCCACTGCGGGCGTTTAACTCGCTGAATCGAATCGGAGCT
TCTGGTCTGAGTAACGAGATTGCTGCCGGTTCCATATTTTTTGCCGTTGGCGGATTATGGTGGCTGGTGGCAGTCATCGG
TAAAATGCCGCAAGCGTTGGGGAAACTCTGGTTACTTTTCAGCATGGCGCTCGGCGTCATTTTCGTCTGGATGATGACCT
GCGTGTATCAAATCGACACCGTGCCAACCTGGCATAACGGTTACACTACGCTGGCTTTCTTCCTGACGGTATTGTTGAGC
GGTCCAATACTTGCTGCCGCAATTCTGCGGGCAGCTCGCGTTACATTTAATACCACACCATTTGCCATCATTAGCGTTCT
GGCGCTGATCGCTTGTGCCGGGGTGATTGTGCTGCAAGGTTTGTCTCTGGCGTCTATTCACTCATCCGTGCAACAAGCCA
GCGCACTGGTACCAGATTACGCCTCCTTACAGGTCTGGCGTGTGGTATTGTTATGCGCAGGTCTTGGATGCTGGCTTTGC
CCGCTCATTCGTCGCCGTGAACCTCACGTTGCCGGACTTATTCTGGGGCTAATCCTCATACTTGGCGGTGAGATGATCGG
GCGTGTGCTCTTTTATGGCCTGCACATGACAGTAGGAATGGCTATTGCAGGTTAA

Upstream 100 bases:

>100_bases
GCGCATTTCACAAAACCCAATATCGTTATCAAACCTAACGCCAACAGCCGCCCGACCGGCGATACCACTGGTTATCTGGC
TAATCCGGAGGAAGTGTAAA

Downstream 100 bases:

>100_bases
CAAATTGGTGCGGGGCAACCCGCACATTTCAGGATGTTAGGAATGACCCATTTTTCACAGCAAGATAATTTTTCTGTCGC
GGCGCGCGTGTTGGGCGCGC

Product: anaerobic dimethyl sulfoxide reductase, C subunit

Products: NA

Alternate protein names: DMSO reductase anchor subunit ynfH

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MGNGWHEWPLVIFTVLGQCVVGALIVSGIGWFAAKNDADRQRIVRGMFFLWLLMGVGFIASVMHLGSPLRAFNSLNRIGA
SGLSNEIAAGSIFFAVGGLWWLVAVIGKMPQALGKLWLLFSMALGVIFVWMMTCVYQIDTVPTWHNGYTTLAFFLTVLLS
GPILAAAILRAARVTFNTTPFAIISVLALIACAGVIVLQGLSLASIHSSVQQASALVPDYASLQVWRVVLLCAGLGCWLC
PLIRRREPHVAGLILGLILILGGEMIGRVLFYGLHMTVGMAIAG

Sequences:

>Translated_284_residues
MGNGWHEWPLVIFTVLGQCVVGALIVSGIGWFAAKNDADRQRIVRGMFFLWLLMGVGFIASVMHLGSPLRAFNSLNRIGA
SGLSNEIAAGSIFFAVGGLWWLVAVIGKMPQALGKLWLLFSMALGVIFVWMMTCVYQIDTVPTWHNGYTTLAFFLTVLLS
GPILAAAILRAARVTFNTTPFAIISVLALIACAGVIVLQGLSLASIHSSVQQASALVPDYASLQVWRVVLLCAGLGCWLC
PLIRRREPHVAGLILGLILILGGEMIGRVLFYGLHMTVGMAIAG
>Mature_283_residues
GNGWHEWPLVIFTVLGQCVVGALIVSGIGWFAAKNDADRQRIVRGMFFLWLLMGVGFIASVMHLGSPLRAFNSLNRIGAS
GLSNEIAAGSIFFAVGGLWWLVAVIGKMPQALGKLWLLFSMALGVIFVWMMTCVYQIDTVPTWHNGYTTLAFFLTVLLSG
PILAAAILRAARVTFNTTPFAIISVLALIACAGVIVLQGLSLASIHSSVQQASALVPDYASLQVWRVVLLCAGLGCWLCP
LIRRREPHVAGLILGLILILGGEMIGRVLFYGLHMTVGMAIAG

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. The C subunit anchors the other two subunits to the membrane and stabilize the catalytic subunits

COG id: COG3302

COG function: function code R; DMSO reductase anchor subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli dmsC

Homologues:

Organism=Escherichia coli, GI1787873, Length=284, Percent_Identity=100, Blast_Score=556, Evalue=1e-160,
Organism=Escherichia coli, GI1787123, Length=286, Percent_Identity=56.993006993007, Blast_Score=293, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YNFH_ECOLI (P76173)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   H64914
- RefSeq:   AP_002211.1
- RefSeq:   NP_416107.1
- ProteinModelPortal:   P76173
- STRING:   P76173
- EnsemblBacteria:   EBESCT00000000607
- EnsemblBacteria:   EBESCT00000016177
- GeneID:   945822
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5261
- KEGG:   eco:b1590
- EchoBASE:   EB3607
- EcoGene:   EG13846
- eggNOG:   COG3302
- GeneTree:   EBGT00050000010789
- HOGENOM:   HBG625162
- OMA:   HEWPLVL
- ProtClustDB:   CLSK870602
- BioCyc:   EcoCyc:G6848-MONOMER
- BioCyc:   MetaCyc:G6848-MONOMER
- Genevestigator:   P76173
- InterPro:   IPR007059

Pfam domain/function: PF04976 DmsC

EC number: NA

Molecular weight: Translated: 30524; Mature: 30393

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x145c18bc)-; HASH(0x14838924)-; HASH(0x14ddcbfc)-; HASH(0x14eec924)-; HASH(0x1246d208)-; HASH(0x13e3556c)-; HASH(0x11aebae0)-; HASH(0x14e352d4)-;

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNGWHEWPLVIFTVLGQCVVGALIVSGIGWFAAKNDADRQRIVRGMFFLWLLMGVGFIA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
SVMHLGSPLRAFNSLNRIGASGLSNEIAAGSIFFAVGGLWWLVAVIGKMPQALGKLWLLF
HHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMALGVIFVWMMTCVYQIDTVPTWHNGYTTLAFFLTVLLSGPILAAAILRAARVTFNTTP
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCH
FAIISVLALIACAGVIVLQGLSLASIHSSVQQASALVPDYASLQVWRVVLLCAGLGCWLC
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
PLIRRREPHVAGLILGLILILGGEMIGRVLFYGLHMTVGMAIAG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
GNGWHEWPLVIFTVLGQCVVGALIVSGIGWFAAKNDADRQRIVRGMFFLWLLMGVGFIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
SVMHLGSPLRAFNSLNRIGASGLSNEIAAGSIFFAVGGLWWLVAVIGKMPQALGKLWLLF
HHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMALGVIFVWMMTCVYQIDTVPTWHNGYTTLAFFLTVLLSGPILAAAILRAARVTFNTTP
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCH
FAIISVLALIACAGVIVLQGLSLASIHSSVQQASALVPDYASLQVWRVVLLCAGLGCWLC
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
PLIRRREPHVAGLILGLILILGGEMIGRVLFYGLHMTVGMAIAG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503