Click here to switch to the map view.

The map label for this gene is lsrR [H]

Identifier: 157160984

GI number: 157160984

Start: 1617110

End: 1618063

Strand: Reverse

Name: lsrR [H]

Synonym: EcHS_A1594

Alternate gene names: 157160984

Gene position: 1618063-1617110 (Counterclockwise)

Preceding gene: 157160992

Following gene: 157160983

Centisome position: 34.85

GC content: 51.05

Gene sequence:

>954_bases
ATGACAATCAACGATTCGGTAATTTCAGAACAGGGAATGTGTGAAGAAGAACAGGTCGCGCGGATCGCGTGGTTTTACTA
CCACGACGGGCTGACCCAGAGTGAGATCAGCGATCGTCTCGGCCTGACACGTTTGAAAGTATCGCGATTGCTGGAGAAAG
GGCATCAGTCCGGCATTATTCGCGTACAGATTAATTCTCGCTTTGAAGGCTGTCTGGAATATGAAACTCAATTACGTCGT
CAGTTTTCGCTGCAACATGTCCGGGTGATCCCTGGGCTTGCGGATGCTGATGTCGGCGGGCGACTAGGGATAGGCGCGGC
GCATATGTTGATGAGTTTACTTCAACCACAACAGATGCTGGCGATTGGTTTTGGCGAGGCAACCATGAATACGCTGCAAC
GCTTAAGTGGTTTTATTTCGTCACAGCAAATTCGCCTGGTCACGCTCTCCGGTGGCGTCGGTTCTTATATGACGGGTATC
GGGCAGCTTAACGCGGCGTGCAGTGTGAATATTATTCCGGCTCCGTTGCGGGCATCCTCCGCTGACATTGCCCGTACGCT
AAAAAATGAAAATTGCGTCAAAGATGTTCTGCTAGCCGCGCAAGCAGCGGATGTGGCGATTGTCGGCATTGGGGCCGTGA
GTCAACAAGACGACGCGACGATCATTCGCTCCGGTTATATCAGCCAGGGCGAACAGTTAATGATTGGCCGAAAAGGGGCG
GTTGGCGACATTTTAGGCTACTTTTTTGATGCAAAAGGTGACGTTGTCACGGATATCAAAATACATAACGAACTGATTGG
CTTACCTTTAAGCGCGCTGAAGACCATACCCGTCCGGGTTGGCGTGGCAGGGGGAGAAAATAAAGCCGAAGCAATTGCCG
CTGCAATGAAAGGCGGTTATATCAACGCACTGGTTACCGATCAGGACACAGCAGCGGCGATTTTACGTAGTTAA

Upstream 100 bases:

>100_bases
ACTCGTAGAGTCAAACTGTGGTTGCCATCACAGATATAAATGCGCAAGAACTGAACAATTGCATTAAAGATTTAAATATG
TTCAAAGTGAAGAATGAATT

Downstream 100 bases:

>100_bases
ATTTGCATGACCTTATTACCGGGAATGATGGAGAACGTATAGAGGAACAGACAGAACGCATAAGCCGAGGATAATCTAAT
GGCTCGACTCTTTACCCCTT

Product: transcriptional repressor LsrR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MTINDSVISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTRLKVSRLLEKGHQSGIIRVQINSRFEGCLEYETQLRR
QFSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGI
GQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGA
VGDILGYFFDAKGDVVTDIKIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS

Sequences:

>Translated_317_residues
MTINDSVISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTRLKVSRLLEKGHQSGIIRVQINSRFEGCLEYETQLRR
QFSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGI
GQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGA
VGDILGYFFDAKGDVVTDIKIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS
>Mature_316_residues
TINDSVISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTRLKVSRLLEKGHQSGIIRVQINSRFEGCLEYETQLRRQ
FSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGIG
QLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGAV
GDILGYFFDAKGDVVTDIKIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS

Specific function: Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsr operon and its own transcription. In the presence of AI-2, lsrR is inactivated by binding phospho-AI-2, leading to the transcriptio

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=317, Percent_Identity=99.3690851735016, Blast_Score=637, Evalue=0.0,
Organism=Escherichia coli, GI87082414, Length=331, Percent_Identity=25.3776435045317, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 33826; Mature: 33695

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTINDSVISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTRLKVSRLLEKGHQSGII
CCCCCCHHCCCCCCCHHHHHHEEEEEEECCCCHHHHHHHHCHHHHHHHHHHHCCCCCCEE
RVQINSRFEGCLEYETQLRRQFSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQML
EEEECCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHCCHHHE
AIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGIGQLNAACSVNIIPAPLRASS
EEECCHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHCCCCEEEEEEECCCCCCCH
ADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGA
HHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEECCCCCCCCEEEEECCCC
VGDILGYFFDAKGDVVTDIKIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGY
HHHHHHHHHCCCCCEEEEEEECCHHHCCCHHHHHCCCEEEEECCCCCHHHHHHHHHCCCE
INALVTDQDTAAAILRS
EEEEEECCHHHHHHHCC
>Mature Secondary Structure 
TINDSVISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTRLKVSRLLEKGHQSGII
CCCCCHHCCCCCCCHHHHHHEEEEEEECCCCHHHHHHHHCHHHHHHHHHHHCCCCCCEE
RVQINSRFEGCLEYETQLRRQFSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQML
EEEECCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHCCHHHE
AIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGIGQLNAACSVNIIPAPLRASS
EEECCHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHCCCCEEEEEEECCCCCCCH
ADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGA
HHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEECCCCCCCCEEEEECCCC
VGDILGYFFDAKGDVVTDIKIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGY
HHHHHHHHHCCCCCEEEEEEECCHHHCCCHHHHHCCCEEEEECCCCCHHHHHHHHHCCCE
INALVTDQDTAAAILRS
EEEEEECCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA