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The map label for this gene is hipB [H]

Identifier: 157160982

GI number: 157160982

Start: 1608999

End: 1609283

Strand: Reverse

Name: hipB [H]

Synonym: EcHS_A1591

Alternate gene names: 157160982

Gene position: 1609283-1608999 (Counterclockwise)

Preceding gene: 157160983

Following gene: 157160981

Centisome position: 34.66

GC content: 44.91

Gene sequence:

>285_bases
TTGCTGTGGACGTATGACATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCG
CCAGCAAAATGGCTGGACGCAGAGCGAGCTGGCGAAAAAAATTGGTATTAAGCAGGCGACGATTTCCAATTTCGAAAACA
ACCCTGACAATACCACGCTCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACGCGAAA
AATGCCTCGCCAGAATCAACAGAACAGCAAAATCTGGAGTGGTAA

Upstream 100 bases:

>100_bases
TATCGCAGCGTTTATCCCGTAGAGCGGATAAGATGTGTTTCCAGATTGACTTATCCTCACTAAAGGATAAAACTTATAAT
ATCCCCTTAAGCGGATAAAC

Downstream 100 bases:

>100_bases
TGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAAG
TATGCACCGGAGTGGTTAGC

Product: DNA-binding transcriptional regulator HipB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 94; Mature: 94

Protein sequence:

>94_residues
MLWTYDMMSFQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISNFENNPDNTTLTTFFKILQSLELSMTLCDAK
NASPESTEQQNLEW

Sequences:

>Translated_94_residues
MLWTYDMMSFQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISNFENNPDNTTLTTFFKILQSLELSMTLCDAK
NASPESTEQQNLEW
>Mature_94_residues
MLWTYDMMSFQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISNFENNPDNTTLTTFFKILQSLELSMTLCDAK
NASPESTEQQNLEW

Specific function: Binds to operator sites with the consensus sequence 5-'TATCCN(8)GGATA-3' and repress the hip operon promoter [H]

COG id: COG1396

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH cro/C1-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787786, Length=88, Percent_Identity=100, Blast_Score=179, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001387
- InterPro:   IPR010982 [H]

Pfam domain/function: PF01381 HTH_3 [H]

EC number: NA

Molecular weight: Translated: 10826; Mature: 10826

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50943 HTH_CROC1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWTYDMMSFQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISNFENNPDNTTL
CCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHCCCCCCCCHHH
TTFFKILQSLELSMTLCDAKNASPESTEQQNLEW
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLWTYDMMSFQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISNFENNPDNTTL
CCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHCCCCCCCCHHH
TTFFKILQSLELSMTLCDAKNASPESTEQQNLEW
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1715862; 9097039; 9278503; 8021189 [H]