Click here to switch to the map view.

The map label for this gene is ddpA [H]

Identifier: 157160963

GI number: 157160963

Start: 1577743

End: 1579293

Strand: Reverse

Name: ddpA [H]

Synonym: EcHS_A1572

Alternate gene names: 157160963

Gene position: 1579293-1577743 (Counterclockwise)

Preceding gene: 157160964

Following gene: 157160962

Centisome position: 34.01

GC content: 50.16

Gene sequence:

>1551_bases
ATGAAGAGATCGATATCGTTTCGTCCCACATTGCTCGCGCTCGTCCTTGCCACAAATTTCCCGGTTGCGCACGCCGCCGT
ACCAAAAGATATGCTGGTGATTGGTAAGGCCGCCGATCCACAAACCCTCGACCCGGCGGTAACAATAGATAATAACGACT
GGACAGTGACCTACCCGTCTTATCAGCGGCTGGTTCAGTACAAAACGGACGGTGATAAAGGCTCAACCGACGTTGAAGGC
GATCTGGCAAGTAGCTGGAAAGCGTCTGACGATCAAAAAGAGTGGACGTTCACCCTGAAAGATAATGCTAAATTTGCCGA
TGGCACACCTGTCACTGCCGAAGCAGTAAAACTTTCTTTTGAGCGGCTACTAAAAATCGGCCAGGGGCCAGCAGAAGCAT
TTCCCAAAGATTTAAAGATTGATGCTCCCGACGAACATACGGTGAAGTTTACCCTTAGCCAGCCATTCGCACCGTTCCTC
TACACGCTGGCGAATGACGGTGCATCCATTATCAATCCGGCGGTGTTAAAGGAACATGCAGCGGATGATGCCCGCGGCTT
CCTCGCGCAAAATACCGCCGGTTCCGGACCATTTATGCTGAAAAGCTGGCAAAAAGGTCAGCAATTAGTTCTGGTGCCAA
ATCCGCATTACCCTGGCAATAAACCGAACTTTAAGCGAGTATCGGTAAAAATTATTGGTGAAAGTGCCTCCCGTCGCCTG
CAGCTCTCCCGTGGTGATATTGACATTGCCGATGCGCTGCCGGTGGATCAACTCAACGCCCTGAAGCAGGAAAACAAAGT
CAATGTGGCAGAGTATCCGTCACTGCGCGTCACCTACCTGTATCTGAATAACAGCAAAGCGCCACTTAATCAGGCGGATC
TGCGTCGGGCCATTTCCTGGTCTACCGATTACCAGGGAATGGTTAACGGCATTCTGAGTGGTAACGGAAAACAGATGCGC
GGCCCGATTCCGGAAGGCATGTGGGGCTACGATGCGACGGCAATGCAATACAACCATGACGAAACGAAAGCCAAAGCTGA
ATGGGATAAAGTGACGAACAAACCCACCAGCCTGACGTTTCTCTATTCTGATAATGATCCGAACTGGGAGCCTATTGCTC
TGGCGACACAATCCAGTCTCAACAAGCTGGGCATCAATGTGAAGCTGGAAAAGCTGGCGAACGCCACCATGCGCGACAGA
GTGGGTAAAGGTGATTACGACATTGCGATTGGCAACTGGAGTCCGGATTTTGCCGACCCGTATATGTTTATGAATTACTG
GTTTGAGTCAGACAAAAAAGGTCTGCCGGGTAACCGCTCGTTCTATGAAAACAGTGAGGTCGATAAGTTACTGCGCAATG
CGCTTGCGACCACCGACCAGACGCAGCGTACCCGGGACTACCAGCAGGCACAGAAAATCGTCATTGATGACGCTGCTTAT
ATGTACCTGTTCCAGAAAAACTACCAACTGGCGATGAACAAAGGGGTGAAAGGCTTTGTGTTCAATCCCATGCTGGAACA
GGTCTTCAATATCAATACCATGAGTAAATAA

Upstream 100 bases:

>100_bases
TTCGAATTACCCCAGGCAGCGAGTTACCCTCTGCTCGCTGATCAATTCTCTTGTTTTATATCCCCTGGCACACAGCACGT
CAGTTAATCAGGAAACTGTC

Downstream 100 bases:

>100_bases
CGTGACCTTCTGGAGTATTTTACGCCAACGCTGCTGGGGGCTGGTGCTCGTGGTGGCGGGCGTCTGCGTGATTACGTTTA
TTATCTCGCATCTGATCCCT

Product: putative ABC transporter periplasmic-binding protein yddS precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MKRSISFRPTLLALVLATNFPVAHAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPSYQRLVQYKTDGDKGSTDVEG
DLASSWKASDDQKEWTFTLKDNAKFADGTPVTAEAVKLSFERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFL
YTLANDGASIINPAVLKEHAADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYPGNKPNFKRVSVKIIGESASRRL
QLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLRVTYLYLNNSKAPLNQADLRRAISWSTDYQGMVNGILSGNGKQMR
GPIPEGMWGYDATAMQYNHDETKAKAEWDKVTNKPTSLTFLYSDNDPNWEPIALATQSSLNKLGINVKLEKLANATMRDR
VGKGDYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYENSEVDKLLRNALATTDQTQRTRDYQQAQKIVIDDAAY
MYLFQKNYQLAMNKGVKGFVFNPMLEQVFNINTMSK

Sequences:

>Translated_516_residues
MKRSISFRPTLLALVLATNFPVAHAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPSYQRLVQYKTDGDKGSTDVEG
DLASSWKASDDQKEWTFTLKDNAKFADGTPVTAEAVKLSFERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFL
YTLANDGASIINPAVLKEHAADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYPGNKPNFKRVSVKIIGESASRRL
QLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLRVTYLYLNNSKAPLNQADLRRAISWSTDYQGMVNGILSGNGKQMR
GPIPEGMWGYDATAMQYNHDETKAKAEWDKVTNKPTSLTFLYSDNDPNWEPIALATQSSLNKLGINVKLEKLANATMRDR
VGKGDYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYENSEVDKLLRNALATTDQTQRTRDYQQAQKIVIDDAAY
MYLFQKNYQLAMNKGVKGFVFNPMLEQVFNINTMSK
>Mature_516_residues
MKRSISFRPTLLALVLATNFPVAHAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPSYQRLVQYKTDGDKGSTDVEG
DLASSWKASDDQKEWTFTLKDNAKFADGTPVTAEAVKLSFERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFL
YTLANDGASIINPAVLKEHAADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYPGNKPNFKRVSVKIIGESASRRL
QLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLRVTYLYLNNSKAPLNQADLRRAISWSTDYQGMVNGILSGNGKQMR
GPIPEGMWGYDATAMQYNHDETKAKAEWDKVTNKPTSLTFLYSDNDPNWEPIALATQSSLNKLGINVKLEKLANATMRDR
VGKGDYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYENSEVDKLLRNALATTDQTQRTRDYQQAQKIVIDDAAY
MYLFQKNYQLAMNKGVKGFVFNPMLEQVFNINTMSK

Specific function: Part of the ABC transporter complex ddpABCDF, which is probably involved in D,D-dipeptide transport [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787762, Length=516, Percent_Identity=99.2248062015504, Blast_Score=1052, Evalue=0.0,
Organism=Escherichia coli, GI1789966, Length=524, Percent_Identity=26.5267175572519, Blast_Score=174, Evalue=9e-45,
Organism=Escherichia coli, GI87081878, Length=538, Percent_Identity=28.2527881040892, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1787495, Length=518, Percent_Identity=26.2548262548263, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1787052, Length=521, Percent_Identity=26.295585412668, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1789887, Length=499, Percent_Identity=26.25250501002, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1787551, Length=467, Percent_Identity=23.1263383297645, Blast_Score=125, Evalue=9e-30,
Organism=Escherichia coli, GI1789397, Length=529, Percent_Identity=24.007561436673, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57630; Mature: 57630

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSISFRPTLLALVLATNFPVAHAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPS
CCCCCCCCHHHHHHHHHCCCCCHHHCCCCCEEEEECCCCCCCCCCEEEEECCCEEEECCC
YQRLVQYKTDGDKGSTDVEGDLASSWKASDDQKEWTFTLKDNAKFADGTPVTAEAVKLSF
HHHHEEEECCCCCCCCCCCCCHHCCCCCCCCCCEEEEEEECCCEECCCCCCHHHHHHHHH
ERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFLYTLANDGASIINPAVLKEHA
HHHHHCCCCHHHHCCCCCEECCCCCCEEEEEECCCCHHHHHHHHCCCHHHCCHHHHHHHC
ADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYPGNKPNFKRVSVKIIGESASRRL
CCHHHCEEECCCCCCCCEEECCCCCCCEEEEECCCCCCCCCCCCEEEEEEEECCCCCCEE
QLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLRVTYLYLNNSKAPLNQADLRRAISW
EEECCCEEHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHCC
STDYQGMVNGILSGNGKQMRGPIPEGMWGYDATAMQYNHDETKAKAEWDKVTNKPTSLTF
CCCCCHHHHHHHCCCCCEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEE
LYSDNDPNWEPIALATQSSLNKLGINVKLEKLANATMRDRVGKGDYDIAIGNWSPDFADP
EECCCCCCCCEEEEEEHHHHHHHCCCEEHHHHHCCHHHHHCCCCCEEEEECCCCCCCCCC
YMFMNYWFESDKKGLPGNRSFYENSEVDKLLRNALATTDQTQRTRDYQQAQKIVIDDAAY
HHEEHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHEEECCCEE
MYLFQKNYQLAMNKGVKGFVFNPMLEQVFNINTMSK
EEEEECCCEEEECCCCCCEEECHHHHHHHCCCCCCC
>Mature Secondary Structure
MKRSISFRPTLLALVLATNFPVAHAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPS
CCCCCCCCHHHHHHHHHCCCCCHHHCCCCCEEEEECCCCCCCCCCEEEEECCCEEEECCC
YQRLVQYKTDGDKGSTDVEGDLASSWKASDDQKEWTFTLKDNAKFADGTPVTAEAVKLSF
HHHHEEEECCCCCCCCCCCCCHHCCCCCCCCCCEEEEEEECCCEECCCCCCHHHHHHHHH
ERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFLYTLANDGASIINPAVLKEHA
HHHHHCCCCHHHHCCCCCEECCCCCCEEEEEECCCCHHHHHHHHCCCHHHCCHHHHHHHC
ADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYPGNKPNFKRVSVKIIGESASRRL
CCHHHCEEECCCCCCCCEEECCCCCCCEEEEECCCCCCCCCCCCEEEEEEEECCCCCCEE
QLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLRVTYLYLNNSKAPLNQADLRRAISW
EEECCCEEHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHCC
STDYQGMVNGILSGNGKQMRGPIPEGMWGYDATAMQYNHDETKAKAEWDKVTNKPTSLTF
CCCCCHHHHHHHCCCCCEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEE
LYSDNDPNWEPIALATQSSLNKLGINVKLEKLANATMRDRVGKGDYDIAIGNWSPDFADP
EECCCCCCCCEEEEEEHHHHHHHCCCEEHHHHHCCHHHHHCCCCCEEEEECCCCCCCCCC
YMFMNYWFESDKKGLPGNRSFYENSEVDKLLRNALATTDQTQRTRDYQQAQKIVIDDAAY
HHEEHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHEEECCCEE
MYLFQKNYQLAMNKGVKGFVFNPMLEQVFNINTMSK
EEEEECCCEEEECCCCCCEEECHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]