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The map label for this gene is nhoA [H]

Identifier: 157160939

GI number: 157160939

Start: 1550836

End: 1551681

Strand: Direct

Name: nhoA [H]

Synonym: EcHS_A1547

Alternate gene names: 157160939

Gene position: 1550836-1551681 (Clockwise)

Preceding gene: 157160937

Following gene: 157160949

Centisome position: 33.4

GC content: 51.54

Gene sequence:

>846_bases
ATGACGCCCATTCTGAATCACTATTTTGCCCGTATTAACTGGTCGGGAGCTGCTGCGGTCAATATTGATACGCTTCGTGC
ATTGCACCTGAAACACAATTGCACCATTCCGTTTGAAAACCTCGACGTTTTGCTGCCGAGGGAAATACAGCTTGATAATC
AATCGCTGGAAGAGAAACTGGTGATAGCCCGTCGTGGCGGTTACTGTTTTGAGCAGAATGGCGTGTTTGAGCGGGTGTTA
CGCGAGCTGGGGTTTAACGTTCGCAGCTTGTTAGGGCGCGTAGTGTTATCAAATCCGCCAGCATTACCGCCGCGCACCCA
TCGTTTGCTGTTGGTGGAACTGGAAGAGGAAAAATGGATTGCTGATGTCGGTTTCGGTGGGCAGACGCTAACCGCGCCGA
TTCGTTTAGTTCCCGATCTCGTGCAGACCACGCCACACGGAGAGTATCGGTTGTTGCAGGAGGGTGATGATTGGGTGTTG
CAGTTTAATCATCATCAGCACTGGCAGTCGATGTACCGTTTTGATCTCTGCGAGCAGCAACAAAGCGATTATGTGATGGG
CAATTTCTGGTCGGCGCACTGGCCGCAGTCGCATTTTCGCCATCATTTGCTGATGTGCCGCCATTTGCCGGACGGCGGCA
AGCTGACACTGACCAATTTTCATTTTACCCATTATGAAAATGGGCACGCGGTGGAGCAGCGAAATCTACCGGATGTGGCG
TCATTATATGCTGTGATGCAAGAACAGTTTGGTCTGGGCGTGGATGATGCGAAACATGGCTTTACCGTGGATGAGTTAGC
GCTGGTGATGGCGGCGTTTGATACGCACCCGGAGGCGGGAAAATAA

Upstream 100 bases:

>100_bases
GCGATTTGCGAACGTGATGCATGTACGCGATCGCACAAAATAGCCGGTGCGGCGTCTATTCCAGGTTATAAGTTGAGAAA
ACCACTAAGGGAAACGCCTG

Downstream 100 bases:

>100_bases
TTTATGTCAGGTTGCCGGATGCGGCGTAAACGCCTTATCCGGCATACATTAGCTCGGTTGTAGACCTGATAAGCGAAGCG
CATCAGGCAACGATTTCAGA

Product: N-hydroxyarylamine O-acetyltransferase

Products: NA

Alternate protein names: Arylamine N-acetyltransferase; Arylhydroxamate N,O-acetyltransferase; NAT102 [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MTPILNHYFARINWSGAAAVNIDTLRALHLKHNCTIPFENLDVLLPREIQLDNQSLEEKLVIARRGGYCFEQNGVFERVL
RELGFNVRSLLGRVVLSNPPALPPRTHRLLLVELEEEKWIADVGFGGQTLTAPIRLVPDLVQTTPHGEYRLLQEGDDWVL
QFNHHQHWQSMYRFDLCEQQQSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENGHAVEQRNLPDVA
SLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTHPEAGK

Sequences:

>Translated_281_residues
MTPILNHYFARINWSGAAAVNIDTLRALHLKHNCTIPFENLDVLLPREIQLDNQSLEEKLVIARRGGYCFEQNGVFERVL
RELGFNVRSLLGRVVLSNPPALPPRTHRLLLVELEEEKWIADVGFGGQTLTAPIRLVPDLVQTTPHGEYRLLQEGDDWVL
QFNHHQHWQSMYRFDLCEQQQSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENGHAVEQRNLPDVA
SLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTHPEAGK
>Mature_280_residues
TPILNHYFARINWSGAAAVNIDTLRALHLKHNCTIPFENLDVLLPREIQLDNQSLEEKLVIARRGGYCFEQNGVFERVLR
ELGFNVRSLLGRVVLSNPPALPPRTHRLLLVELEEEKWIADVGFGGQTLTAPIRLVPDLVQTTPHGEYRLLQEGDDWVLQ
FNHHQHWQSMYRFDLCEQQQSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENGHAVEQRNLPDVAS
LYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTHPEAGK

Specific function: Unknown

COG id: COG2162

COG function: function code Q; Arylamine N-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arylamine N-acetyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI237649132, Length=290, Percent_Identity=23.7931034482759, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI237649130, Length=290, Percent_Identity=23.7931034482759, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI237649128, Length=284, Percent_Identity=23.5915492957746, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI237649126, Length=284, Percent_Identity=23.5915492957746, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI237649124, Length=284, Percent_Identity=23.5915492957746, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI237649122, Length=284, Percent_Identity=23.5915492957746, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI237649119, Length=284, Percent_Identity=23.5915492957746, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI42741671, Length=284, Percent_Identity=23.5915492957746, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI237649009, Length=284, Percent_Identity=23.5915492957746, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787736, Length=281, Percent_Identity=99.288256227758, Blast_Score=579, Evalue=1e-167,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001447 [H]

Pfam domain/function: PF00797 Acetyltransf_2 [H]

EC number: =2.3.1.118 [H]

Molecular weight: Translated: 32301; Mature: 32170

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPILNHYFARINWSGAAAVNIDTLRALHLKHNCTIPFENLDVLLPREIQLDNQSLEEKL
CCCHHCCCEEEEECCCCEEEEHHHHEEEEECCCCCCCCCCCCEECCCEEECCCHHHHHHE
VIARRGGYCFEQNGVFERVLRELGFNVRSLLGRVVLSNPPALPPRTHRLLLVELEEEKWI
EEEECCCEEEECCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEE
ADVGFGGQTLTAPIRLVPDLVQTTPHGEYRLLQEGDDWVLQFNHHQHWQSMYRFDLCEQQ
EECCCCCCEEEHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
QSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENGHAVEQRNLPDVA
CCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCCCCHHH
SLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTHPEAGK
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TPILNHYFARINWSGAAAVNIDTLRALHLKHNCTIPFENLDVLLPREIQLDNQSLEEKL
CCHHCCCEEEEECCCCEEEEHHHHEEEEECCCCCCCCCCCCEECCCEEECCCHHHHHHE
VIARRGGYCFEQNGVFERVLRELGFNVRSLLGRVVLSNPPALPPRTHRLLLVELEEEKWI
EEEECCCEEEECCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCEE
ADVGFGGQTLTAPIRLVPDLVQTTPHGEYRLLQEGDDWVLQFNHHQHWQSMYRFDLCEQQ
EECCCCCCEEEHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
QSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENGHAVEQRNLPDVA
CCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCCCCHHH
SLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTHPEAGK
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]