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The map label for this gene is tehB [H]

Identifier: 157160906

GI number: 157160906

Start: 1521991

End: 1522584

Strand: Direct

Name: tehB [H]

Synonym: EcHS_A1511

Alternate gene names: 157160906

Gene position: 1521991-1522584 (Clockwise)

Preceding gene: 157160905

Following gene: 157160907

Centisome position: 32.78

GC content: 45.96

Gene sequence:

>594_bases
ATGATCATTCGTGACGAAAACTATTTTACTGATAAATATGAATTAACCCGCACACACTCTGAAGTAATGGAAGCGGTGAA
AGTGGTTAAACCGGGTAAAACGCTGGATCTGGGCTGTGGCAATGGTCGTAACAGTCTTTACCTGGCAGCCAATGGTTATG
ATGTTGACGCATGGGATAAAAATGCCATGAGTATCGCCAACGTCGAGCGCATTAAATCTATTGAAAATCTGGATAATTTA
CACACTCGGGTCGTTGATCTGAATAACCTCACATTTGCTGGACAGTACGATTTTATTCTTTCGACTGTGGTGCTGATGTT
CCTTGAGGCTAAAACCATCCCAGGGCTGATTGCCAATATGCAACGTTGCACGAAACCTGGCGGTTACAACCTGATTGTGG
CGGCGATGGATAGCGCTGATTATCCATGTACCGTCGGCTTCCCGTTTGCCTTCAAAGAGAGAGAATTACGTCGATATTAC
GAAGGCTGGGAGATGGTGAAATACAATGAAGACGTCGGCGAGCTGCACCGCACCGACGCCAACGGTAATCGTATTAAACT
GCGTTTCGCCACGATGCTGGCACGTAAAAAATGA

Upstream 100 bases:

>100_bases
TTATTGCAATACTGCTCATCCGTACTTTTGCGCTTCTGATGCAGGGAAAATTGTTAGTCAGAACCGAGCGCGCCGTTTTA
ATGAAAGCAGAGGACGAAGA

Downstream 100 bases:

>100_bases
CCCGGTAAGAACAAAGCGCGTGAAAATTCCCCACGCTGAGATAGTTTACTGTTCTTCTTTTCGGTAAGCATATTTTTTAT
CGAAGGGATGTGAAATTAAT

Product: tellurite resistance protein TehB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MIIRDENYFTDKYELTRTHSEVMEAVKVVKPGKTLDLGCGNGRNSLYLAANGYDVDAWDKNAMSIANVERIKSIENLDNL
HTRVVDLNNLTFAGQYDFILSTVVLMFLEAKTIPGLIANMQRCTKPGGYNLIVAAMDSADYPCTVGFPFAFKERELRRYY
EGWEMVKYNEDVGELHRTDANGNRIKLRFATMLARKK

Sequences:

>Translated_197_residues
MIIRDENYFTDKYELTRTHSEVMEAVKVVKPGKTLDLGCGNGRNSLYLAANGYDVDAWDKNAMSIANVERIKSIENLDNL
HTRVVDLNNLTFAGQYDFILSTVVLMFLEAKTIPGLIANMQRCTKPGGYNLIVAAMDSADYPCTVGFPFAFKERELRRYY
EGWEMVKYNEDVGELHRTDANGNRIKLRFATMLARKK
>Mature_197_residues
MIIRDENYFTDKYELTRTHSEVMEAVKVVKPGKTLDLGCGNGRNSLYLAANGYDVDAWDKNAMSIANVERIKSIENLDNL
HTRVVDLNNLTFAGQYDFILSTVVLMFLEAKTIPGLIANMQRCTKPGGYNLIVAAMDSADYPCTVGFPFAFKERELRRYY
EGWEMVKYNEDVGELHRTDANGNRIKLRFATMLARKK

Specific function: Probable S-adenosyl-L-methionine dependent methyltransferase that is responsible for tellurite resistance when present in high copy number. Binds tellurite and S-adenosyl- L-methionine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable). Note=Probably a peripheral membrane protein that interacts with TehA [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TehB family [H]

Homologues:

Organism=Escherichia coli, GI1787700, Length=197, Percent_Identity=96.9543147208122, Blast_Score=396, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004537
- InterPro:   IPR015985 [H]

Pfam domain/function: PF03848 TehB [H]

EC number: NA

Molecular weight: Translated: 22466; Mature: 22466

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIRDENYFTDKYELTRTHSEVMEAVKVVKPGKTLDLGCGNGRNSLYLAANGYDVDAWDK
CEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEECCCCCCCCCC
NAMSIANVERIKSIENLDNLHTRVVDLNNLTFAGQYDFILSTVVLMFLEAKTIPGLIANM
CCHHHHHHHHHHHHHHHHHHHHEEEECCCEEECCCHHHHHHHHHHHHHHHCCCCHHHHHH
QRCTKPGGYNLIVAAMDSADYPCTVGFPFAFKERELRRYYEGWEMVKYNEDVGELHRTDA
HHHCCCCCCEEEEEEECCCCCCEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHCCCC
NGNRIKLRFATMLARKK
CCCEEEEEEEHHHHCCC
>Mature Secondary Structure
MIIRDENYFTDKYELTRTHSEVMEAVKVVKPGKTLDLGCGNGRNSLYLAANGYDVDAWDK
CEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEECCCCCCCCCC
NAMSIANVERIKSIENLDNLHTRVVDLNNLTFAGQYDFILSTVVLMFLEAKTIPGLIANM
CCHHHHHHHHHHHHHHHHHHHHEEEECCCEEECCCHHHHHHHHHHHHHHHCCCCHHHHHH
QRCTKPGGYNLIVAAMDSADYPCTVGFPFAFKERELRRYYEGWEMVKYNEDVGELHRTDA
HHHCCCCCCEEEEEEECCCCCCEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHCCCC
NGNRIKLRFATMLARKK
CCCEEEEEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2060788; 9097039; 9278503; 8169225 [H]