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The map label for this gene is sirB2

Identifier: 157160718

GI number: 157160718

Start: 1315363

End: 1315755

Strand: Direct

Name: sirB2

Synonym: EcHS_A1318

Alternate gene names: 157160718

Gene position: 1315363-1315755 (Clockwise)

Preceding gene: 157160717

Following gene: 157160719

Centisome position: 28.33

GC content: 47.58

Gene sequence:

>393_bases
ATGACAAGTTTTTCTACACTGCTTAGTGTTCATCTTATTAGTATCGCGCTTTCTGTTGGGCTATTAACCTTACGTTTCTG
GCTACGTTATCAGAAGCATCCACAGGCATTTGCTCGCTGGACGCGCATTGTGCCGCCGGTTGTCGATACGCTGTTACTGT
TAAGCGGCATTGCGTTGATGGCTAAAGCGCACATCCTGCCATTTTCCGGGCAGGCACAGTGGCTGACTGAAAAGCTGTTT
GGAGTTATCATTTATATCGTTTTGGGTTTTATTGCACTCGATTATCGTCGTATGCACAGTCAGCAGGCGCGCATTATTGC
CTTCCCGCTGGCGTTGGTGGTGCTGTACATCATCATTAAACTCGCCACCACAAAAGTACCGTTACTGGGGTAA

Upstream 100 bases:

>100_bases
AAGCGGTGCGACAAGCATTTATCCTCGCGGGGTATCATGACGTCGAAACCTGCCGTGACTATGGTGATAACGAGCGCGTA
ACGCTCGGCCGCTATTATCA

Downstream 100 bases:

>100_bases
GTCATGAGATCGTTAGCTGATTTCGAATTTAATAAAGCGCCATTGTGCGAAGGCATGATCCTGGCTTGCGAAGCAATCCG
CCGCGATTTTCCCTCGCAAG

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 130; Mature: 129

Protein sequence:

>130_residues
MTSFSTLLSVHLISIALSVGLLTLRFWLRYQKHPQAFARWTRIVPPVVDTLLLLSGIALMAKAHILPFSGQAQWLTEKLF
GVIIYIVLGFIALDYRRMHSQQARIIAFPLALVVLYIIIKLATTKVPLLG

Sequences:

>Translated_130_residues
MTSFSTLLSVHLISIALSVGLLTLRFWLRYQKHPQAFARWTRIVPPVVDTLLLLSGIALMAKAHILPFSGQAQWLTEKLF
GVIIYIVLGFIALDYRRMHSQQARIIAFPLALVVLYIIIKLATTKVPLLG
>Mature_129_residues
TSFSTLLSVHLISIALSVGLLTLRFWLRYQKHPQAFARWTRIVPPVVDTLLLLSGIALMAKAHILPFSGQAQWLTEKLFG
VIIYIVLGFIALDYRRMHSQQARIIAFPLALVVLYIIIKLATTKVPLLG

Specific function: Unknown

COG id: COG3094

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787464, Length=130, Percent_Identity=100, Blast_Score=254, Evalue=9e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SIRB2_ECOLI (Q46755)

Other databases:

- EMBL:   U18555
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   I83571
- RefSeq:   AP_001838.1
- RefSeq:   NP_415731.1
- ProteinModelPortal:   Q46755
- STRING:   Q46755
- EnsemblBacteria:   EBESCT00000000838
- EnsemblBacteria:   EBESCT00000017572
- GeneID:   945781
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW1204
- KEGG:   eco:b1213
- EchoBASE:   EB4041
- EcoGene:   EG14293
- eggNOG:   COG3094
- GeneTree:   EBGT00050000009699
- HOGENOM:   HBG644082
- OMA:   GAWLTEK
- ProtClustDB:   PRK10278
- BioCyc:   EcoCyc:G6630-MONOMER
- Genevestigator:   Q46755
- InterPro:   IPR007360
- PIRSF:   PIRSF005610

Pfam domain/function: PF04247 SirB

EC number: NA

Molecular weight: Translated: 14639; Mature: 14508

Theoretical pI: Translated: 11.31; Mature: 11.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x13955384)-; HASH(0x142671e4)-; HASH(0x13a13588)-; HASH(0x146a55cc)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSFSTLLSVHLISIALSVGLLTLRFWLRYQKHPQAFARWTRIVPPVVDTLLLLSGIALM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
AKAHILPFSGQAQWLTEKLFGVIIYIVLGFIALDYRRMHSQQARIIAFPLALVVLYIIIK
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATTKVPLLG
HHHHCCCCCH
>Mature Secondary Structure 
TSFSTLLSVHLISIALSVGLLTLRFWLRYQKHPQAFARWTRIVPPVVDTLLLLSGIALM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
AKAHILPFSGQAQWLTEKLFGVIIYIVLGFIALDYRRMHSQQARIIAFPLALVVLYIIIK
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATTKVPLLG
HHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7543480; 8905232; 9278503