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The map label for this gene is ycfQ [H]

Identifier: 157160638

GI number: 157160638

Start: 1231905

End: 1232615

Strand: Reverse

Name: ycfQ [H]

Synonym: EcHS_A1234

Alternate gene names: 157160638

Gene position: 1232615-1231905 (Counterclockwise)

Preceding gene: 157160640

Following gene: 157160629

Centisome position: 26.54

GC content: 49.93

Gene sequence:

>711_bases
ATGGGATCTGGACTGGTGAACGGAGGTGATTATTTTTATAATAACCTTTCATTCACAGTCACCAGGTACAACGGCATCAT
GGCAACTGACTCAACACAATGTGTAAAAAAAAGCCGTGGCCGCCCAAAAGTGTTCGACAGGGATGCCGCGCTTGATAAGG
CCATGAAATTGTTCTGGCAACACGGTTATGAAGCGACTTCTCTTGCGGACCTCGTCGAAGCGACCGGAGCCAAAGCGCCC
ACGCTATACGCGGAATTTACCAACAAAGAGGGGTTATTTCGTGCCGTTCTCGACCGCTATATCGATCGTTTTGCCGCTAA
GCATGAAGCACAGCTGTTTTGTGAAGAGAAAAGCGTGGAGTCTGCGCTGGCTGACTATTTTGCTGCCATCGCCAACTGCT
TTACCAGCAAAGACACCCCGGCAGGCTGCTTCATGATCAACAACTGCACCACCCTCTCCCCAGATTCAGGAGATATCGCC
AATACGTTGAAATCACGCCATGCGATGCAAGAGCGCACTTTGCAGCAGTTTTTATGTCAACGACAAGCGCGCGGGGAAAT
CCCGACCCACTGTGACGTGACACATCTGGCAGAATTCCTTAATTGTATTATTCAGGGGATGTCGATCAGCGCACGCGAAG
GTGCATCGCTGGAAAAACTAATGCAGATTGCCGGAACGACTTTGCGTTTATGGCCCGAACTGGTGAAATAA

Upstream 100 bases:

>100_bases
GATAGATGTGATCTGGATCACATACAAGATATTTTTTATAACAATCATTAATTAATTTAAAAATCTTTAAATTTCAGTTA
AATAGAAAGCAATTATTTTT

Downstream 100 bases:

>100_bases
GTCGCAAAAAAAGCCCCTCAGCCTGAGCGAATGAGGGGCCAAATTGCAGAGTACAGCCTTGTTATACTTTGTTATTCAAA
ATCAGTTGCCCATTACTATC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MGSGLVNGGDYFYNNLSFTVTRYNGIMATDSTQCVKKSRGRPKVFDRDAALDKAMKLFWQHGYEATSLADLVEATGAKAP
TLYAEFTNKEGLFRAVLDRYIDRFAAKHEAQLFCEEKSVESALADYFAAIANCFTSKDTPAGCFMINNCTTLSPDSGDIA
NTLKSRHAMQERTLQQFLCQRQARGEIPTHCDVTHLAEFLNCIIQGMSISAREGASLEKLMQIAGTTLRLWPELVK

Sequences:

>Translated_236_residues
MGSGLVNGGDYFYNNLSFTVTRYNGIMATDSTQCVKKSRGRPKVFDRDAALDKAMKLFWQHGYEATSLADLVEATGAKAP
TLYAEFTNKEGLFRAVLDRYIDRFAAKHEAQLFCEEKSVESALADYFAAIANCFTSKDTPAGCFMINNCTTLSPDSGDIA
NTLKSRHAMQERTLQQFLCQRQARGEIPTHCDVTHLAEFLNCIIQGMSISAREGASLEKLMQIAGTTLRLWPELVK
>Mature_235_residues
GSGLVNGGDYFYNNLSFTVTRYNGIMATDSTQCVKKSRGRPKVFDRDAALDKAMKLFWQHGYEATSLADLVEATGAKAPT
LYAEFTNKEGLFRAVLDRYIDRFAAKHEAQLFCEEKSVESALADYFAAIANCFTSKDTPAGCFMINNCTTLSPDSGDIAN
TLKSRHAMQERTLQQFLCQRQARGEIPTHCDVTHLAEFLNCIIQGMSISAREGASLEKLMQIAGTTLRLWPELVK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081833, Length=210, Percent_Identity=99.5238095238095, Blast_Score=438, Evalue=1e-124,
Organism=Escherichia coli, GI87082397, Length=187, Percent_Identity=30.4812834224599, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 26208; Mature: 26077

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSGLVNGGDYFYNNLSFTVTRYNGIMATDSTQCVKKSRGRPKVFDRDAALDKAMKLFWQ
CCCCCCCCCHHHCCCCEEEEEEECCEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
HGYEATSLADLVEATGAKAPTLYAEFTNKEGLFRAVLDRYIDRFAAKHEAQLFCEEKSVE
CCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SALADYFAAIANCFTSKDTPAGCFMINNCTTLSPDSGDIANTLKSRHAMQERTLQQFLCQ
HHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RQARGEIPTHCDVTHLAEFLNCIIQGMSISAREGASLEKLMQIAGTTLRLWPELVK
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHC
>Mature Secondary Structure 
GSGLVNGGDYFYNNLSFTVTRYNGIMATDSTQCVKKSRGRPKVFDRDAALDKAMKLFWQ
CCCCCCCCHHHCCCCEEEEEEECCEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
HGYEATSLADLVEATGAKAPTLYAEFTNKEGLFRAVLDRYIDRFAAKHEAQLFCEEKSVE
CCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SALADYFAAIANCFTSKDTPAGCFMINNCTTLSPDSGDIANTLKSRHAMQERTLQQFLCQ
HHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RQARGEIPTHCDVTHLAEFLNCIIQGMSISAREGASLEKLMQIAGTTLRLWPELVK
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]