Click here to switch to the map view.

The map label for this gene is nagZ [H]

Identifier: 157160634

GI number: 157160634

Start: 1227775

End: 1228800

Strand: Direct

Name: nagZ [H]

Synonym: EcHS_A1230

Alternate gene names: 157160634

Gene position: 1227775-1228800 (Clockwise)

Preceding gene: 157160633

Following gene: 157160635

Centisome position: 26.44

GC content: 52.92

Gene sequence:

>1026_bases
GTGGGTCCAGTAATGTTGGATGTCGAAGGTTACGAACTGGACGCGGAAGAGCGTGAAATACTGGCGCATCCGCTGGTGGG
AGGGCTGATTCTCTTTACGCGTAACTATCATGATCCTGCCCAGTTACGTGAACTGGTGCGCCAGATCCGCGCAGCTTCGC
GCAATCATCTGGTGGTGGCGGTTGATCAGGAAGGTGGACGCGTGCAGCGTTTTCGTGAAGGTTTTACCCGCTTGCCAGCG
GCGCAATCATTCGCTGCGCTGTCAGGAATGGAAGAGGGTGGCAAACTGGCGCAGGAGGCAGGTTGGTTGATGGCCAGCGA
AATGATCGCTATGGATATTGATATCAGCTTTGCGCCTGTGCTGGATGTCGGGCATATCAGCGCGGCGATTGGCGAGCGTT
CTTATCATGCCGATCCACAAAAAGCCCTGGCAATTGCCAGCCGGTTTATTGATGGTATGCATGAAGCCGGAATGAAAACG
ACCGGGAAACACTTCCCAGGACACGGTGCAGTAACGGCAGACTCACACAAAGAAACACCGTGCGATCCACGTCCACAAGC
GGAGATTCGCGCTAAAGATATGTCGGTCTTCAGTTCCTTAATCCGCGAAAATAAACTCGACGCCATTATGCCTGCGCATG
TGATCTACAGTGATGTTGATCCGCGTCCGGCGAGCGGTTCTCCCTACTGGCTGAAAACCGTTTTGCGTCAGGAACTGGGT
TTTGACGGCGTGATTTTCTCTGACGATTTATCGATGGAAGGTGCCGTGATTATGGGCAGTTATGCCGAACGCGGGCAGGC
ATCACTGGATGCGGGTTGCGATATGATCCTGGTCTGCAATAATCGTAAAGGGGCCGTCAGCGTGTTAGATAATCTGTCAC
CGATCAAGGCAGAACGTGTTACACGTTTGTATCATAAAGGTTCATTTTCGCGACAGGAACTGATGGACTCGGCTCGCTGG
AAAGCGATCAGCGCCCGTCTGAATCAGTTACATGAACGCTGGCAGGAAGAGAAAGCAGGTCACTAA

Upstream 100 bases:

>100_bases
TGGTTTGAGTACCGCTGGCGACAAACCGGCGATCAACAATTTATCAGGCTGGCCGATGACACCTGGCGGCAGCTATTAAT
AAAACAATAAGGAGAGCAGT

Downstream 100 bases:

>100_bases
CCCTGGCTTATGTGAGGAAGCGATGATTATCTATTTACACGGTTTTGACTCTAACAGTCCGGGTAACCACGAGAAAGTCT
TACAATTGCAGTTTATTGAC

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MGPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRELVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPA
AQSFAALSGMEEGGKLAQEAGWLMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPQKALAIASRFIDGMHEAGMKT
TGKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSSLIRENKLDAIMPAHVIYSDVDPRPASGSPYWLKTVLRQELG
FDGVIFSDDLSMEGAVIMGSYAERGQASLDAGCDMILVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSARW
KAISARLNQLHERWQEEKAGH

Sequences:

>Translated_341_residues
MGPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRELVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPA
AQSFAALSGMEEGGKLAQEAGWLMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPQKALAIASRFIDGMHEAGMKT
TGKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSSLIRENKLDAIMPAHVIYSDVDPRPASGSPYWLKTVLRQELG
FDGVIFSDDLSMEGAVIMGSYAERGQASLDAGCDMILVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSARW
KAISARLNQLHERWQEEKAGH
>Mature_340_residues
GPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRELVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPAA
QSFAALSGMEEGGKLAQEAGWLMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPQKALAIASRFIDGMHEAGMKTT
GKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSSLIRENKLDAIMPAHVIYSDVDPRPASGSPYWLKTVLRQELGF
DGVIFSDDLSMEGAVIMGSYAERGQASLDAGCDMILVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSARWK
AISARLNQLHERWQEEKAGH

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides [H]

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787350, Length=341, Percent_Identity=99.1202346041056, Blast_Score=697, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022956
- InterPro:   IPR019800
- InterPro:   IPR001764
- InterPro:   IPR017853 [H]

Pfam domain/function: PF00933 Glyco_hydro_3 [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 37574; Mature: 37443

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00775 GLYCOSYL_HYDROL_F3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRELVRQIRAASRNHLVVA
CCCEEEEECCCCCCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEE
VDQEGGRVQRFREGFTRLPAAQSFAALSGMEEGGKLAQEAGWLMASEMIAMDIDISFAPV
ECCCCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCH
LDVGHISAAIGERSYHADPQKALAIASRFIDGMHEAGMKTTGKHFPGHGAVTADSHKETP
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCC
CDPRPQAEIRAKDMSVFSSLIRENKLDAIMPAHVIYSDVDPRPASGSPYWLKTVLRQELG
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHCC
FDGVIFSDDLSMEGAVIMGSYAERGQASLDAGCDMILVCNNRKGAVSVLDNLSPIKAERV
CCCEEEECCCCCCCEEEECCCHHCCCCCCCCCCCEEEEECCCCCHHHHHHCCCCHHHHHH
TRLYHKGSFSRQELMDSARWKAISARLNQLHERWQEEKAGH
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRELVRQIRAASRNHLVVA
CCEEEEECCCCCCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEE
VDQEGGRVQRFREGFTRLPAAQSFAALSGMEEGGKLAQEAGWLMASEMIAMDIDISFAPV
ECCCCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCH
LDVGHISAAIGERSYHADPQKALAIASRFIDGMHEAGMKTTGKHFPGHGAVTADSHKETP
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCC
CDPRPQAEIRAKDMSVFSSLIRENKLDAIMPAHVIYSDVDPRPASGSPYWLKTVLRQELG
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHCC
FDGVIFSDDLSMEGAVIMGSYAERGQASLDAGCDMILVCNNRKGAVSVLDNLSPIKAERV
CCCEEEECCCCCCCEEEECCCHHCCCCCCCCCCCEEEEECCCCCHHHHHHCCCCHHHHHH
TRLYHKGSFSRQELMDSARWKAISARLNQLHERWQEEKAGH
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA