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The map label for this gene is csgD [H]

Identifier: 157160562

GI number: 157160562

Start: 1165442

End: 1166092

Strand: Reverse

Name: csgD [H]

Synonym: EcHS_A1158

Alternate gene names: 157160562

Gene position: 1166092-1165442 (Counterclockwise)

Preceding gene: 157160563

Following gene: 157160561

Centisome position: 25.11

GC content: 41.94

Gene sequence:

>651_bases
ATGTTTAATGAAGTCCATAGTATTCATGGTCATACATTATTGTTGATCACTAAACCTTCTTTGCAGGCGACAGCTCTCTT
GCAGCACCTTAAACAATCGCTGGCAATTACAGGAAAATTACATAATATTCAACGTTCTCTGGACGATATCTCTTCAGGCT
CTATTATTCTTCTGGATATGATGGAAGCGGATAAAAAGCTTATCCATTATTGGCAGGATACTTTGAGCAGGAAAAACAAC
AATATCAAAATATTGTTGCTAAATACGCCTGAAGATTACCCGTACCGCGACATTGAAAACTGGCCTCATATCAACGGCGT
TTTTTATTCCATGGAGGATCAAGAACGTGTTGTCAATGGGTTGCAAGGCGTCCTGCGCGGCGAATGCTACTTTACGCAAA
AGCTTGCCAGCTACCTGATTACGCATTCAGGTAACTATCGTTATAACAGCACGGAATCAGCCCTCCTTACTCATCGGGAA
AAAGAGATCCTGAATAAGCTGCGTATCGGCGCGTCTAATAACGAGATCGCTCGTTCGTTGTTCATCAGCGAAAATACGGT
TAAAACGCATCTTTATAATCTTTTCAAGAAGATAGCCGTAAAAAACCGGACACAAGCGGTTTCCTGGGCAAACGATAACC
TCAGGCGATAA

Upstream 100 bases:

>100_bases
TTACTACACACAGCAGTGCAACATCTGTCAGTACTTCTGGTGCTTCTATTTTAGAGGCAGCTGTCAGGTGTGCGATCAAT
AAAAAAAGCGGGGTTTCATC

Downstream 100 bases:

>100_bases
AGCCATGAAACGTTATTTACGCTGGATTGTGGCGGCAGAATTTCTGTTCGCCGCAGGGAATCTTCACGCCGTTGAGGTAG
AAGTCCCGGGATTGCTAACT

Product: DNA-binding transcriptional regulator CsgD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MFNEVHSIHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQRSLDDISSGSIILLDMMEADKKLIHYWQDTLSRKNN
NIKILLLNTPEDYPYRDIENWPHINGVFYSMEDQERVVNGLQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHRE
KEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR

Sequences:

>Translated_216_residues
MFNEVHSIHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQRSLDDISSGSIILLDMMEADKKLIHYWQDTLSRKNN
NIKILLLNTPEDYPYRDIENWPHINGVFYSMEDQERVVNGLQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHRE
KEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR
>Mature_216_residues
MFNEVHSIHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQRSLDDISSGSIILLDMMEADKKLIHYWQDTLSRKNN
NIKILLLNTPEDYPYRDIENWPHINGVFYSMEDQERVVNGLQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHRE
KEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR

Specific function: The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA t

COG id: COG2771

COG function: function code K; DNA-binding HTH domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787277, Length=216, Percent_Identity=99.537037037037, Blast_Score=442, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016032
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE [H]

EC number: NA

Molecular weight: Translated: 24946; Mature: 24946

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNEVHSIHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQRSLDDISSGSIILLDM
CCCCHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEH
MEADKKLIHYWQDTLSRKNNNIKILLLNTPEDYPYRDIENWPHINGVFYSMEDQERVVNG
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEECCCHHHHHHHH
LQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHREKEILNKLRIGASNNEIARSL
HHHHHHCCHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
FISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR
HHCCCHHHHHHHHHHHHHHHCCCHHEEEECCCCCCC
>Mature Secondary Structure
MFNEVHSIHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQRSLDDISSGSIILLDM
CCCCHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEH
MEADKKLIHYWQDTLSRKNNNIKILLLNTPEDYPYRDIENWPHINGVFYSMEDQERVVNG
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEECCCHHHHHHHH
LQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHREKEILNKLRIGASNNEIARSL
HHHHHHCCHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
FISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR
HHCCCHHHHHHHHHHHHHHHCCCHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8817489; 8905232; 9278503 [H]