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The map label for this gene is cbpA [H]

Identifier: 157160521

GI number: 157160521

Start: 1123691

End: 1124611

Strand: Reverse

Name: cbpA [H]

Synonym: EcHS_A1112

Alternate gene names: 157160521

Gene position: 1124611-1123691 (Counterclockwise)

Preceding gene: 157160525

Following gene: 157160520

Centisome position: 24.22

GC content: 52.88

Gene sequence:

>921_bases
ATGGAATTAAAGGATTATTACGCCATCATGGGCGTGAAACCGACGGACGATCTCAAGACAATCAAGACCGCCTATCGTCG
ACTTGCCCGCAAATACCATCCTGATGTCAGCAAAGAACCGGATGCCGAAGCCCGCTTCAAAGAGGTCGCTGAAGCCTGGG
AAGTGTTAAGTGATGAACAACGTCGCGCTGAGTATGATCAGATGTGGCAACATCGCAACGATCCGCAATTTAACCGTCAG
TTCCACCATGGCGACGGTCAGAGTTTTAACGCCGAAGATTTTGACGATATCTTCTCGTCAATTTTCGGTCAGCATGCCCG
CCAGAGCCGTCAACGCCCCGCCACACGCGGCCACGATATTGAAATCGAAGTGGCGGTATTCCTCGAAGAAACGCTTACTG
AGCATAAGCGTACCATCAGCTATAACCTGCCGGTTTATAACGCCTTTGGCATGATCGAACAGGAAATTCCGAAAACGCTG
AATGTGAAGATCCCGGCGGGCGTCGGCAATGGTCAACGCATCCGTCTGAAAGGCCAGGGGACGCCGGGCGAAAACGGCGG
TCCAAATGGCGATTTGTGGCTGGTGATTCATATTGCGCCACATCCGCTGTTTGATATTGTCGGCCAGGATCTGGAAATTG
TGGTGCCGGTTAGCCCGTGGGAAGCGGCGCTGGGTGCTAAAGTCACCGTTCCAACACTGAAAGAAAGCATTTTGCTGACT
ATCCCGCCAGGCAGCCAGGCCGGGCAACGATTGCGCGTTAAAGGCAAAGGTCTGGTGAGCAAAAAACAGACCGGCGATCT
GTATGCGGTACTGAAAATCGTGATGCCGCCGAAACCGGATGAAAACACTGCCGCGCTGTGGCAGCAACTGGCAGACGCCC
AGTCGTCTTTTGATCCACGTAAAGATTGGGGGAAAGCATAA

Upstream 100 bases:

>100_bases
TTCTGTGTTGGCATATGAAATTTTGAGGATTACCCTACACTTATAGGAGTTACCTTACAGGGGTTCCTTCAATTTGTGTT
GATTTACGCGAGATAACGCT

Downstream 100 bases:

>100_bases
TGGCTAATGTTACGGTGACTTTTACTATTACCGAATTTTGCCTGCATACCGGCATCTCTGAAGAGGAGTTGAATGAAATT
GTCGGTTTGGGGGTGGTTGA

Product: curved DNA-binding protein CbpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQ
FHHGDGQSFNAEDFDDIFSSIFGQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTL
NVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVSPWEAALGAKVTVPTLKESILLT
IPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPRKDWGKA

Sequences:

>Translated_306_residues
MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQ
FHHGDGQSFNAEDFDDIFSSIFGQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTL
NVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVSPWEAALGAKVTVPTLKESILLT
IPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPRKDWGKA
>Mature_306_residues
MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQ
FHHGDGQSFNAEDFDDIFSSIFGQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTL
NVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVSPWEAALGAKVTVPTLKESILLT
IPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPRKDWGKA

Specific function: DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adapt

COG id: COG2214

COG function: function code O; DnaJ-class molecular chaperone

Gene ontology:

Cell location: Cytoplasm, nucleoid [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI5453690, Length=337, Percent_Identity=27.299703264095, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI6631085, Length=323, Percent_Identity=29.1021671826625, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI56549115, Length=342, Percent_Identity=27.1929824561404, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI201862587, Length=342, Percent_Identity=27.1929824561404, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI201862518, Length=342, Percent_Identity=27.1929824561404, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI7706495, Length=297, Percent_Identity=28.956228956229, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI9558755, Length=113, Percent_Identity=44.2477876106195, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI39204547, Length=301, Percent_Identity=26.578073089701, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI194328758, Length=254, Percent_Identity=30.3149606299213, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI194328760, Length=254, Percent_Identity=30.3149606299213, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI205360840, Length=107, Percent_Identity=40.1869158878505, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI205360838, Length=107, Percent_Identity=40.1869158878505, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI72534740, Length=103, Percent_Identity=36.8932038834951, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4504511, Length=135, Percent_Identity=34.0740740740741, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI194306642, Length=105, Percent_Identity=40, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI194306640, Length=105, Percent_Identity=40, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI56687498, Length=63, Percent_Identity=46.031746031746, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI17388799, Length=107, Percent_Identity=39.2523364485981, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4885495, Length=107, Percent_Identity=39.2523364485981, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787235, Length=306, Percent_Identity=100, Blast_Score=633, Evalue=0.0,
Organism=Escherichia coli, GI1786197, Length=355, Percent_Identity=33.8028169014084, Blast_Score=175, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17553096, Length=343, Percent_Identity=26.530612244898, Blast_Score=110, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17553098, Length=343, Percent_Identity=26.530612244898, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17534355, Length=324, Percent_Identity=29.6296296296296, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI212645553, Length=343, Percent_Identity=27.1137026239067, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17507263, Length=62, Percent_Identity=50, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324265, Length=137, Percent_Identity=35.7664233576642, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320888, Length=100, Percent_Identity=42, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45549272, Length=373, Percent_Identity=28.1501340482574, Blast_Score=114, Evalue=6e-26,
Organism=Drosophila melanogaster, GI45552813, Length=373, Percent_Identity=28.1501340482574, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI45552811, Length=373, Percent_Identity=28.1501340482574, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24658562, Length=341, Percent_Identity=30.4985337243402, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24658555, Length=341, Percent_Identity=30.4985337243402, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI85726398, Length=352, Percent_Identity=29.8295454545455, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI19920464, Length=336, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI18858081, Length=343, Percent_Identity=26.530612244898, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24668492, Length=64, Percent_Identity=46.875, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646562, Length=62, Percent_Identity=50, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24646560, Length=62, Percent_Identity=50, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24646558, Length=62, Percent_Identity=50, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24646556, Length=62, Percent_Identity=50, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21357547, Length=62, Percent_Identity=50, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C [H]

EC number: NA

Molecular weight: Translated: 34455; Mature: 34455

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00636 DNAJ_1 ; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQ
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHH
RRAEYDQMWQHRNDPQFNRQFHHGDGQSFNAEDFDDIFSSIFGQHARQSRQRPATRGHDI
HHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCE
EIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTLNVKIPAGVGNGQRIRLKGQG
EEEEHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECC
TPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVSPWEAALGAKVTVPTLKESILLT
CCCCCCCCCCCEEEEEEECCCCHHHHCCCCEEEEEECCCHHHHHCCEEECCCCCCCEEEE
IPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPR
ECCCCCCCCEEEEECCCCCCCCCCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHHHCCCCC
KDWGKA
HHCCCC
>Mature Secondary Structure
MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQ
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHH
RRAEYDQMWQHRNDPQFNRQFHHGDGQSFNAEDFDDIFSSIFGQHARQSRQRPATRGHDI
HHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCE
EIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTLNVKIPAGVGNGQRIRLKGQG
EEEEHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECC
TPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVSPWEAALGAKVTVPTLKESILLT
CCCCCCCCCCCEEEEEEECCCCHHHHCCCCEEEEEECCCHHHHHCCEEECCCCCCCEEEE
IPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPR
ECCCCCCCCEEEEECCCCCCCCCCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHHHCCCCC
KDWGKA
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA