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The map label for this gene is torA [H]

Identifier: 157160517

GI number: 157160517

Start: 1120092

End: 1122638

Strand: Direct

Name: torA [H]

Synonym: EcHS_A1108

Alternate gene names: 157160517

Gene position: 1120092-1122638 (Clockwise)

Preceding gene: 157160516

Following gene: 157160518

Centisome position: 24.12

GC content: 55.28

Gene sequence:

>2547_bases
ATGAACAATAACGATCTCTTTCAGGCATCACGTCGGCGTTTTCTGGCACAACTCGGCGGCTTAACCGTCGCCGGGATGCT
GGGGCCGTCATTGTTAACGCCGCGACGTGCGACTGCGGCGCAAGCGGCGACTGACGCTGTCATCTCGAAAGAGGGCATTC
TTACCGGGTCGCACTGGGGGGCTATCCGCGCGACGGTGAAGGATGGTCGCTTTGTGGCGGCAAAACCGTTCGAACTGGAT
AAATATCCGTCGAAAATGATTGCCGGATTGCCGGATCACGTACACAACGCGGCGCGTATTCGTTATCCGATGGTACGCGT
GGACTGGCTGCGTAAGCGCCATCTCAGCGATACCTCCCAGCGCGGTGATAACCGTTTTGTGCGCGTGAGCTGGGATGAAG
CCCTCGACATGTTCTATGAAGAACTGGAACGCGTGCAGAAAACTCACGGGCCGAGTGCCTTGCTGACCGCCAGTGGTTGG
CAATCGACGGGGATGTTCCATAACGCTTCGGGGATGCTGGCGAAAGCTATTGCCTTGCATGGTAATAGCGTTGGTACGGG
CGGAGATTACTCTACCGGTGCTGCGCAGGTGATCCTGCCGCGCATAGTCGGTTCGATGGAAGTGTATGAACAGCAAACCT
CCTGGCCGCTGGTATTGCAGAACAGCAAAACCATTGTGCTGTGGGGCTCCGATTTGCTGAAAAACCAGCAAGCGAACTGG
TGGTGCCCGGATCACGATGTTTATGAATATTACGCGCAGCTAAAAGCGAAAGTCGCCGCCGGTGAAATTGAGGTCATCAG
CATCGATCCGGTTGTCACATCCACCCATGAGTATCTGGGGCGCGAGCATGTGAAGCACATTGCGGTTAACCCGCAAACTG
ACGTGCCGCTGCAACTGGCGCTGGCACATACGCTGTACAGTGAAAACCTGTACGACAAAAACTTCCTTGCTAACTACTGT
GTGGGTTTTGAGCAGTTCCTGCCGTATCTGCTGGGTGAGAAAGACGGTCAGCCGAAAGATGCCGCATGGGCTGAAAAACT
GACCGGCATTGATGCCGAAACCATTCGTGGGCTGGCGCGGCAGATGGCGGCGAACAGAACGCAAATTATTGCTGGCTGGT
GCGTGCAGCGTATGCAGCACGGTGAACAGTGGGCGTGGATGATTGTGGTTCTGGCGGCGATGCTGGGGCAAATTGGCCTG
CCAGGTGGTGGTTTTGGTTTTGGCTGGCACTACAACGGCGCAGGCACGCCGGGGCGTAAAGGCGTTATTCTGAGTGGTTT
CTCCGGCTCTACGTCGATTCCGCCTGTTCACGACAACAGTGACTACAAAGGCTACAGCAGCACTATTCCGATTGCCCGTT
TTATCGATGCGATCCTCGAACCGGGGAAAGTGATCAACTGGAACGGTAAATCGGTAAAACTGCCGCCGCTGAATATGTGT
ATTTTTGCCGGAACTAACCCATTCCATCGCCATCAGCAGATCAACCGCATTATTGAAGGCTTGCGCAAGCTGGAAACGGT
TATCGCCATAGATAACCAGTGGACCTCAACCTGCCGCTTTGCCGATATCGTACTGCCTGCGACCACGCAGTTTGAGCGTA
ACGATCTCGACCAGTACGGCAATCACTCCAACCGTGGCATTATCGCCATGAAACAGGTGGTGCCGCCGCAGTTCGAGGCG
CGCAACGACTTCGATATTTTCCGCGAGCTGTGCCGTCGCTTTAATCGCGAAGAAGCCTTTACCGAAGGGCTGGACGAAAT
GGGCTGGCTGAAACGCATCTGGCAGGAAGGTGTACAGCAAGGCAAAGGACGCGGCGTTCATCTGCCAGCGTTTGATGACT
TCTGGAATAACAAAGAGTACGTCGAGTTTGACCATCCGCAGATGTTTGTTCGCCACCAGGCATTCCGCGAAGATCCGGAT
CTCGAACCGCTGGGCACGCCGAGTGGCCTGATTGAGATCTACTCGAAAACTATCGCCGATATGAACTACGACGATTGTCA
GGGGCATCCGATGTGGTTTGAGAAAATCGAACGCTCCCACGGTGGGCCTGGCTCGCAAAAGTATCCGTTGCATCTGCAAT
CTGTGCATCCGGATTTCCGACTTCACTCGCAGTTATGTGAGTCGGAAACGCTGCGTCAGCAATATACGGTAGCGGGTAAA
GAGCCAGTATTCATTAACCCGCAGGATGCCAGCGCGCGCGGTATTCGTAACGGTGATGTGGTACGCGTCTTTAACGCTCG
CGGTCAGGTGTTGGCAGGGGCAGTGGTTTCTGACCGCTATGCACCCGGCGTGGCACGAATTCACGAAGGGGCATGGTACG
ATCCAGATAAAGGCGGCGAGCCTGGTGCGCTGTGCAAATACGGTAACCCCAACGTGTTGACCATCGACATCGGTACATCG
CAGCTGGCGCAGGCGACCAGTGCGCACACTACGCTGGTGGAAATTGAGAAGTACAACGGAACAGTGGAGCAGGTGACGGC
GTTTAACGGCCCCGTGGAGATGGTGGCGCAGTGCGAATATGTTCCCGCGTCGCAGGTGAAATCATGA

Upstream 100 bases:

>100_bases
GTCTCGATAAACGTGAAGAACGCACCTTGTTGAAATATCTGCAAATGAATGCGTCTGACACCGCAGGTAAGGCTCACGGC
GATAAGAAGGAAGAAAAATA

Downstream 100 bases:

>100_bases
CCACGCTGACAGCACAACAGATTGCCTGTGTTTACGCCTGGCTAGCGCAGTTGTTCTCCCGTGAGCTGGACGATGAACAA
CTGACGCAAATCGCCAGTGC

Product: trimethylamine-N-oxide reductase

Products: NA

Alternate protein names: TMAO reductase 1; Trimethylamine oxidase 1 [H]

Number of amino acids: Translated: 848; Mature: 848

Protein sequence:

>848_residues
MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAATDAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELD
KYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGW
QSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRIVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANW
WCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLALAHTLYSENLYDKNFLANYC
VGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGL
PGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIPIARFIDAILEPGKVINWNGKSVKLPPLNMC
IFAGTNPFHRHQQINRIIEGLRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEA
RNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFDHPQMFVRHQAFREDPD
LEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGK
EPVFINPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIGTS
QLAQATSAHTTLVEIEKYNGTVEQVTAFNGPVEMVAQCEYVPASQVKS

Sequences:

>Translated_848_residues
MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAATDAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELD
KYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGW
QSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRIVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANW
WCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLALAHTLYSENLYDKNFLANYC
VGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGL
PGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIPIARFIDAILEPGKVINWNGKSVKLPPLNMC
IFAGTNPFHRHQQINRIIEGLRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEA
RNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFDHPQMFVRHQAFREDPD
LEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGK
EPVFINPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIGTS
QLAQATSAHTTLVEIEKYNGTVEQVTAFNGPVEMVAQCEYVPASQVKS
>Mature_848_residues
MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAATDAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELD
KYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGW
QSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRIVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANW
WCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLALAHTLYSENLYDKNFLANYC
VGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGL
PGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIPIARFIDAILEPGKVINWNGKSVKLPPLNMC
IFAGTNPFHRHQQINRIIEGLRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEA
RNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFDHPQMFVRHQAFREDPD
LEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGK
EPVFINPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIGTS
QLAQATSAHTTLVEIEKYNGTVEQVTAFNGPVEMVAQCEYVPASQVKS

Specific function: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787231, Length=848, Percent_Identity=99.7641509433962, Blast_Score=1770, Evalue=0.0,
Organism=Escherichia coli, GI87081994, Length=828, Percent_Identity=43.9613526570048, Blast_Score=664, Evalue=0.0,
Organism=Escherichia coli, GI145693196, Length=790, Percent_Identity=42.6582278481013, Blast_Score=611, Evalue=1e-176,
Organism=Escherichia coli, GI87081797, Length=761, Percent_Identity=31.9316688567674, Blast_Score=300, Evalue=3e-82,
Organism=Escherichia coli, GI1787870, Length=860, Percent_Identity=29.3023255813954, Blast_Score=270, Evalue=3e-73,
Organism=Escherichia coli, GI171474008, Length=752, Percent_Identity=30.0531914893617, Blast_Score=258, Evalue=1e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311
- InterPro:   IPR011887 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.7.2.3 [H]

Molecular weight: Translated: 94457; Mature: 94457

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2 ; PS00932 MOLYBDOPTERIN_PROK_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAATDAVISKEGILTGSHWG
CCCCHHHHHHHHHHHHHHCCCEEEHHCCCHHCCCCHHHHHHHHHHHHHHCCCEEECCCCC
AIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQ
EEEEEECCCEEEEECCCCCCCCHHHHHHCCCHHHCCHHHHCCCHHHHHHHHHHHCCCHHH
RGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGWQSTGMFHNASGMLAKAIALH
CCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCCHHHHHHHHC
GNSVGTGGDYSTGAAQVILPRIVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANW
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECHHHHCCCCCCC
WCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLA
CCCCCHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHEEECCCCCCCCHHHH
LAHTLYSENLYDKNFLANYCVGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLAR
HHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHH
QMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGLPGGGFGFGWHYNGAGTPGRK
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCC
GVILSGFSGSTSIPPVHDNSDYKGYSSTIPIARFIDAILEPGKVINWNGKSVKLPPLNMC
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEECCCCEEECCCCCEE
IFAGTNPFHRHQQINRIIEGLRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYG
EEECCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHC
NHSNRGIIAMKQVVPPQFEARNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQ
CCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHH
GKGRGVHLPAFDDFWNNKEYVEFDHPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIAD
CCCCEEECCCHHHHCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
MNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGK
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
EPVFINPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGE
CCEEECCCCCCCCCCCCCCEEEEECCCCCEEECHHHHCCCCCCHHHHCCCCCCCCCCCCC
PGALCKYGNPNVLTIDIGTSQLAQATSAHTTLVEIEKYNGTVEQVTAFNGPVEMVAQCEY
CCCEEECCCCCEEEEECCHHHHHHHHCCCEEEEEEECCCCCHHHHHHCCCCHHHHHHCCC
VPASQVKS
CCHHHCCC
>Mature Secondary Structure
MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAATDAVISKEGILTGSHWG
CCCCHHHHHHHHHHHHHHCCCEEEHHCCCHHCCCCHHHHHHHHHHHHHHCCCEEECCCCC
AIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQ
EEEEEECCCEEEEECCCCCCCCHHHHHHCCCHHHCCHHHHCCCHHHHHHHHHHHCCCHHH
RGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGWQSTGMFHNASGMLAKAIALH
CCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCCHHHHHHHHC
GNSVGTGGDYSTGAAQVILPRIVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANW
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECHHHHCCCCCCC
WCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLA
CCCCCHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHEEECCCCCCCCHHHH
LAHTLYSENLYDKNFLANYCVGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLAR
HHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHH
QMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGLPGGGFGFGWHYNGAGTPGRK
HHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCC
GVILSGFSGSTSIPPVHDNSDYKGYSSTIPIARFIDAILEPGKVINWNGKSVKLPPLNMC
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEECCCCEEECCCCCEE
IFAGTNPFHRHQQINRIIEGLRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYG
EEECCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHC
NHSNRGIIAMKQVVPPQFEARNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQ
CCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHH
GKGRGVHLPAFDDFWNNKEYVEFDHPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIAD
CCCCEEECCCHHHHCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
MNYDDCQGHPMWFEKIERSHGGPGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGK
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
EPVFINPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGE
CCEEECCCCCCCCCCCCCCEEEEECCCCCEEECHHHHCCCCCCHHHHCCCCCCCCCCCCC
PGALCKYGNPNVLTIDIGTSQLAQATSAHTTLVEIEKYNGTVEQVTAFNGPVEMVAQCEY
CCCEEECCCCCEEEEECCHHHHHHHHCCCEEEEEEECCCCCHHHHHHCCCCHHHHHHCCC
VPASQVKS
CCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]