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The map label for this gene is ycbX

Identifier: 157160468

GI number: 157160468

Start: 1068105

End: 1069214

Strand: Reverse

Name: ycbX

Synonym: EcHS_A1056

Alternate gene names: 157160468

Gene position: 1069214-1068105 (Counterclockwise)

Preceding gene: 157160475

Following gene: 157160459

Centisome position: 23.03

GC content: 50.45

Gene sequence:

>1110_bases
GTGGCGACATTAATCCGGCTTTTTATTCATCCTGTTAAATCGATGCGCGGCATTGGTCTTACACATGCTCTGGCAGATGT
CAGTGGTCTGGCCTTCGATCGCATCTTTATGATCACGGAACCTGACGGTACGTTTATTACCGCTCGCCAGTTTCCCCAGA
TGGTACGGTTTACTCCTTCACCTGTGCATGATGGCTTGCATCTCACCGCACCAGATGGCAGTAGCGCATATGTTCGTTTT
GCTGATTTCGCCACACAAGACGCACCAACCGAAGTTTGGGGCACACATTTTACCGCGCGAATTGCGCCAGACGCGATCAA
CAAATGGCTAAGTGGATTTTTCTCCCGCGAAGTGCAATTACGCTGGGTGGGGCCACAAATGACCCGGCGCGTGAAACGCC
ACAACACTGTACCTCTGTCATTTGCTGATGGCTATCCTTACCTTCTTGCTAACGAAGCCTCGTTACGTGATCTCCAACAA
CGTTGTCCGGCCAGTGTAAAAATGGAGCAATTCCGCCCCAATCTGGTGGTTTCCGGCGCGTCAGCCTGGGAAGAAGATCG
CTGGAAAGTGATTCGCATTGGTGATGTGGTGTTTGATGTGGTTAAACCTTGTAGCCGCTGTATTTTCACCACCGTCAGCC
CAGAAAAAGGGCAAAAACATCCGGCAGGCGAACCATTAAAAACATTGCAATCTTTCCGCACTGCCCAGGATAACGGCGAT
GTCGATTTTGGTCAGAATTTAATTGCCCGTAATAGCGGCGTGATTCGCGTTGGCGATGAGGTGGAAATTCTGGCAACGGC
TCCGGCAAAAATTTACGGCGCAGCTGCCGCTGATGATACCGCCAACATCACGCAACAACCGGACGCAAATGTAGATATTG
ACTGGCAGGGACAGGCATTTCGTGGAAATAACCAACAGGTGTTGCTGGAGCAATTAGAAAATCAGGGAATTCGTATCCCT
TATTCTTGCCGCGCGGGCATTTGTGGAAGTTGCCGTGTTCAGCTTTTAGAAGGCGAAGTCACGCCGCTGAAAAAATCAGC
AATGGGCGATGATGGCACCATTCTTTGCTGTAGCTGTGTACCGAAGACTGCACTTAAGTTGGCGCGTTAG

Upstream 100 bases:

>100_bases
AGCCTAATGGGACAGGCGCTAAGAAAATTGTTGCGCATTATAGCTAATAAGCGCGTCATGTCATAAAGTTGAGGGCTTAT
TTTCATTTGAGGACCGCACC

Downstream 100 bases:

>100_bases
ACTGCCTGTTCGAAGCTGAAGCTGTCAACATTAACCTGCGGTTTCAGCCTGTCGTTCATGATTTTAATGGCGTCGCCCAA
CTGCATCGCGCGACCCGCAA

Product: MOSC domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MATLIRLFIHPVKSMRGIGLTHALADVSGLAFDRIFMITEPDGTFITARQFPQMVRFTPSPVHDGLHLTAPDGSSAYVRF
ADFATQDAPTEVWGTHFTARIAPDAINKWLSGFFSREVQLRWVGPQMTRRVKRHNTVPLSFADGYPYLLANEASLRDLQQ
RCPASVKMEQFRPNLVVSGASAWEEDRWKVIRIGDVVFDVVKPCSRCIFTTVSPEKGQKHPAGEPLKTLQSFRTAQDNGD
VDFGQNLIARNSGVIRVGDEVEILATAPAKIYGAAAADDTANITQQPDANVDIDWQGQAFRGNNQQVLLEQLENQGIRIP
YSCRAGICGSCRVQLLEGEVTPLKKSAMGDDGTILCCSCVPKTALKLAR

Sequences:

>Translated_369_residues
MATLIRLFIHPVKSMRGIGLTHALADVSGLAFDRIFMITEPDGTFITARQFPQMVRFTPSPVHDGLHLTAPDGSSAYVRF
ADFATQDAPTEVWGTHFTARIAPDAINKWLSGFFSREVQLRWVGPQMTRRVKRHNTVPLSFADGYPYLLANEASLRDLQQ
RCPASVKMEQFRPNLVVSGASAWEEDRWKVIRIGDVVFDVVKPCSRCIFTTVSPEKGQKHPAGEPLKTLQSFRTAQDNGD
VDFGQNLIARNSGVIRVGDEVEILATAPAKIYGAAAADDTANITQQPDANVDIDWQGQAFRGNNQQVLLEQLENQGIRIP
YSCRAGICGSCRVQLLEGEVTPLKKSAMGDDGTILCCSCVPKTALKLAR
>Mature_368_residues
ATLIRLFIHPVKSMRGIGLTHALADVSGLAFDRIFMITEPDGTFITARQFPQMVRFTPSPVHDGLHLTAPDGSSAYVRFA
DFATQDAPTEVWGTHFTARIAPDAINKWLSGFFSREVQLRWVGPQMTRRVKRHNTVPLSFADGYPYLLANEASLRDLQQR
CPASVKMEQFRPNLVVSGASAWEEDRWKVIRIGDVVFDVVKPCSRCIFTTVSPEKGQKHPAGEPLKTLQSFRTAQDNGDV
DFGQNLIARNSGVIRVGDEVEILATAPAKIYGAAAADDTANITQQPDANVDIDWQGQAFRGNNQQVLLEQLENQGIRIPY
SCRAGICGSCRVQLLEGEVTPLKKSAMGDDGTILCCSCVPKTALKLAR

Specific function: Unknown

COG id: COG3217

COG function: function code R; Uncharacterized Fe-S protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MOSC domain

Homologues:

Organism=Homo sapiens, GI224600454, Length=289, Percent_Identity=32.8719723183391, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI31542713, Length=280, Percent_Identity=31.0714285714286, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI157388923, Length=241, Percent_Identity=23.2365145228216, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1787179, Length=369, Percent_Identity=100, Blast_Score=766, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17540702, Length=276, Percent_Identity=30.7971014492754, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17561286, Length=258, Percent_Identity=31.0077519379845, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71990971, Length=255, Percent_Identity=31.3725490196078, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25147498, Length=238, Percent_Identity=27.3109243697479, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI45550400, Length=289, Percent_Identity=29.4117647058824, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI17647607, Length=249, Percent_Identity=27.710843373494, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YCBX_ECOLI (P75863)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   B64835
- RefSeq:   AP_001577.1
- RefSeq:   NP_415467.1
- ProteinModelPortal:   P75863
- SMR:   P75863
- DIP:   DIP-28068N
- IntAct:   P75863
- STRING:   P75863
- EnsemblBacteria:   EBESCT00000001812
- EnsemblBacteria:   EBESCT00000014979
- GeneID:   945563
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5126
- KEGG:   eco:b0947
- EchoBASE:   EB3480
- EcoGene:   EG13716
- eggNOG:   COG3217
- GeneTree:   EBGT00050000010983
- HOGENOM:   HBG607918
- OMA:   RVPYSCR
- ProtClustDB:   CLSK879856
- BioCyc:   EcoCyc:G6487-MONOMER
- Genevestigator:   P75863
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR005302
- InterPro:   IPR005303
- InterPro:   IPR011037
- Gene3D:   G3DSA:3.10.20.30

Pfam domain/function: PF00111 Fer2; PF03473 MOSC; PF03476 MOSC_N; SSF54292 Ferredoxin; SSF50800 PK_B_barrel_like

EC number: NA

Molecular weight: Translated: 40645; Mature: 40514

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS00197 2FE2S_FER_1; PS51085 2FE2S_FER_2; PS51340 MOSC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLIRLFIHPVKSMRGIGLTHALADVSGLAFDRIFMITEPDGTFITARQFPQMVRFTPS
CHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCEEEHHHCCHHHCCCCC
PVHDGLHLTAPDGSSAYVRFADFATQDAPTEVWGTHFTARIAPDAINKWLSGFFSREVQL
CCCCCCEEECCCCCCEEEEEECCCCCCCCCHHHCCCEEEEECHHHHHHHHHHHHCCCEEE
RWVGPQMTRRVKRHNTVPLSFADGYPYLLANEASLRDLQQRCPASVKMEQFRPNLVVSGA
EEECHHHHHHHHHCCCCEEEECCCCCEEEECCHHHHHHHHHCCCCCCHHHCCCCEEEECC
SAWEEDRWKVIRIGDVVFDVVKPCSRCIFTTVSPEKGQKHPAGEPLKTLQSFRTAQDNGD
CCCCCCCEEEEEEHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCC
VDFGQNLIARNSGVIRVGDEVEILATAPAKIYGAAAADDTANITQQPDANVDIDWQGQAF
CCCCCHHHHCCCCEEEECCCEEEEEECCHHHEECCCCCCCCCCCCCCCCCEEEEECCCEE
RGNNQQVLLEQLENQGIRIPYSCRAGICGSCRVQLLEGEVTPLKKSAMGDDGTILCCSCV
CCCCHHHHHHHHHCCCEEEEHHCCCCCCCCCEEEEECCCCCCCHHHCCCCCCCEEEECCC
PKTALKLAR
CHHHHHHCC
>Mature Secondary Structure 
ATLIRLFIHPVKSMRGIGLTHALADVSGLAFDRIFMITEPDGTFITARQFPQMVRFTPS
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCEEEHHHCCHHHCCCCC
PVHDGLHLTAPDGSSAYVRFADFATQDAPTEVWGTHFTARIAPDAINKWLSGFFSREVQL
CCCCCCEEECCCCCCEEEEEECCCCCCCCCHHHCCCEEEEECHHHHHHHHHHHHCCCEEE
RWVGPQMTRRVKRHNTVPLSFADGYPYLLANEASLRDLQQRCPASVKMEQFRPNLVVSGA
EEECHHHHHHHHHCCCCEEEECCCCCEEEECCHHHHHHHHHCCCCCCHHHCCCCEEEECC
SAWEEDRWKVIRIGDVVFDVVKPCSRCIFTTVSPEKGQKHPAGEPLKTLQSFRTAQDNGD
CCCCCCCEEEEEEHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCC
VDFGQNLIARNSGVIRVGDEVEILATAPAKIYGAAAADDTANITQQPDANVDIDWQGQAF
CCCCCHHHHCCCCEEEECCCEEEEEECCHHHEECCCCCCCCCCCCCCCCCEEEEECCCEE
RGNNQQVLLEQLENQGIRIPYSCRAGICGSCRVQLLEGEVTPLKKSAMGDDGTILCCSCV
CCCCHHHHHHHHHCCCEEEEHHCCCCCCCCCEEEEECCCCCCCHHHCCCCCCCEEEECCC
PKTALKLAR
CHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503