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The map label for this gene is smtA

Identifier: 157160442

GI number: 157160442

Start: 1033875

End: 1034660

Strand: Direct

Name: smtA

Synonym: EcHS_A1028

Alternate gene names: 157160442

Gene position: 1033875-1034660 (Clockwise)

Preceding gene: 157160440

Following gene: 157160443

Centisome position: 22.26

GC content: 51.53

Gene sequence:

>786_bases
ATGCAGGATCGCAATTTTGATGATATTGCGGAAAAGTTTTCCCGTAACATTTACGGCACCACCAAAGGGCAGCTTCGACA
GGCTATTCTGTGGCAGGATCTCGATCGCGTGCTGGCGGAAATGGGCCCGCAAAAACTGCGTGTGCTGGATGCTGGCGGTG
GAGAAGGGCAGACCGCAATCAAAATGGCCGAGCGTGGGCATCAGGTCATTTTATGCGATCTTTCTGCGCAGATGATCGAC
CGCGCAAAACAGGCGGCAGAAGCAAAAGGTGTGAGCGACAACATGCAATTTATACATTGCGCCGCTCAGGATGTTGCTTC
GCATTTGGAAACGCCCGTTGATCTGATATTGTTCCATGCGGTGCTCGAGTGGGTGGCTGATCCCCGCAGCGTATTGCAGA
CCCTGTGGTCAGTGTTGCGTCCAGGCGGCGTGTTGTCGTTAATGTTCTACAATGCGCATGGTTTGTTGATGCATAACATG
GTCGCCGGGAATTTTGATTACGTGCAGGCGGGAATGCCGAAAAAGAAAAAACGGACGCTTTCGCCAGATTATCCACGCGA
CCCGGCGCAGGTTTATCTGTGGCTGGAAGAAGCTGGTTGGCAAATTATGGGTAAGACAGGCGTTCGCGTGTTTCATGATT
ATCTGCGCGAGAAACACCAGCAGCGCGACTGCTATGAAGCATTACTTGAATTAGAAACGCGTTATTGCCGTCAGGAACCG
TATATTACCCTGGGGCGTTATATTCATGTCACCGCGCGCAAACCGCAGAGCAAGGATAAAGTATGA

Upstream 100 bases:

>100_bases
ATCGCCAGCGATATTACACCAGACGGGTTCATTCTCGCCGTGGCTGTGACAAAATAGCGTCTTTATCAGAAAACGTCTTA
GCCAACCGGTGGAGAAAGCA

Downstream 100 bases:

>100_bases
GTGAATTTTCCCAGACAGTCCCCGAACTGGTTGCCTGGGCCAGAAAAAATGACTTCTCCATCTCGCTGCCGGTAGACCGA
CTCTCTTTTCTGCTGGCGGT

Product: putative metallothionein SmtA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMID
RAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNM
VAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP
YITLGRYIHVTARKPQSKDKV

Sequences:

>Translated_261_residues
MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMID
RAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNM
VAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP
YITLGRYIHVTARKPQSKDKV
>Mature_261_residues
MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMID
RAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNM
VAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP
YITLGRYIHVTARKPQSKDKV

Specific function: Unknown

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787151, Length=261, Percent_Identity=100, Blast_Score=546, Evalue=1e-157,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SMTA_ECOLI (P36566)

Other databases:

- EMBL:   D26440
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   H64831
- RefSeq:   AP_001551.1
- RefSeq:   NP_415441.1
- ProteinModelPortal:   P36566
- SMR:   P36566
- STRING:   P36566
- EnsemblBacteria:   EBESCT00000000959
- EnsemblBacteria:   EBESCT00000017673
- GeneID:   945547
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW0904
- KEGG:   eco:b0921
- EchoBASE:   EB2086
- EcoGene:   EG12167
- eggNOG:   COG0500
- GeneTree:   EBGT00050000011865
- HOGENOM:   HBG297935
- OMA:   LEMELAH
- ProtClustDB:   PRK11036
- BioCyc:   EcoCyc:EG12167-MONOMER
- Genevestigator:   P36566
- InterPro:   IPR013216

Pfam domain/function: PF08241 Methyltransf_11

EC number: NA

Molecular weight: Translated: 29815; Mature: 29815

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCHHHH
KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA
HHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL
HHHHHCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCHHHHCCCCHHHCCCC
SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP
CCCCCCCHHHEEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YITLGRYIHVTARKPQSKDKV
CEEECCEEEEEECCCCCCCCC
>Mature Secondary Structure
MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAI
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCHHHH
KMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHA
HHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
VLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVAGNFDYVQAGMPKKKKRTL
HHHHHCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCHHHHCCCCHHHCCCC
SPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP
CCCCCCCHHHEEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YITLGRYIHVTARKPQSKDKV
CEEECCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7513784; 8905232; 9278503; 8566713