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The map label for this gene is ybiT

Identifier: 157160298

GI number: 157160298

Start: 882566

End: 884158

Strand: Direct

Name: ybiT

Synonym: EcHS_A0877

Alternate gene names: 157160298

Gene position: 882566-884158 (Clockwise)

Preceding gene: 157160296

Following gene: 157160299

Centisome position: 19.01

GC content: 52.67

Gene sequence:

>1593_bases
GTGTTAGTTTCCAGTAACGTCACCATGCAGTTCGGCAGTAAGCCGTTGTTTGAAAACATTTCCGTCAAATTTGGCGGCGG
CAACCGTTACGGCCTGATTGGCGCGAACGGTAGTGGTAAATCCACCTTTATGAAGATCCTCGGCGGCGACCTTGAGCCGA
CGCTGGGTAACGTTTCCCTCGATCCCAACGAGCGCATTGGTAAACTGCGTCAGGATCAGTTTGCCTTTGAAGAGTTCACT
GTGCTGGATACGGTGATCATGGGGCATAAAGAGTTGTGGGAAGTGAAGCAGGAGCGCGACCGCATCTATGCTTTGCCGGA
AATGAGTGAAGAAGACGGCTATAAAGTGGCCGATCTGGAAGTTAAATACGGCGAAATGGACGGTTACTCTGCGGAAGCTC
GCGCCGGTGAACTGTTGCTTGGCGTGGGAATTCCAGTGGAACAGCACTACGGCCCGATGAGTGAAGTTGCTCCTGGCTGG
AAGCTGCGTGTGCTTCTGGCGCAGGCGCTGTTTGCTGATCCGGATATTCTCCTGCTCGACGAACCGACCAACAACCTCGA
CATCGACACCATTCGCTGGCTGGAACAGGTGCTGAACGAGCGTGACAGCACCATGATCATCATCTCGCACGACCGTCACT
TCCTTAACATGGTCTGTACCCACATGGCGGATCTGGATTACGGCGAGCTGCGCGTTTATCCGGGTAACTACGATGAGTAC
ATGACGGCGGCGACCCAGGCGCGTGAACGTCTGCTGGCCGATAACGCCAAGAAGAAAGCGCAGATTGCTGAGTTGCAATC
TTTCGTTAGCCGCTTTAGCGCCAACGCCTCGAAATCTCGCCAGGCAACTTCGCGCGCGCGCCAGATTGATAAAATCAAAC
TGGAAGAGGTGAAAGCCTCCAGCCGTCAGAACCCGTTCATCCGTTTTGAACAGGATAAGAAACTGTTCCGTAACGCGCTG
GAAGTGGAAGGTCTGACCAAAGGGTTTGATAACGGTCCGCTGTTTAAAAATCTCAACCTGCTGCTGGAAGTGGGTGAAAA
ACTGGCGGTACTGGGTACCAACGGCGTCGGTAAATCAACGCTGCTGAAAACGCTGGTGGGCGATCTGCAACCGGACAGCG
GCACCGTAAAATGGTCTGAGAACGCGCGCATTGGTTACTATGCTCAGGACCACGAATATGAGTTTGAAAATGATCTGACC
GTGTTCGAATGGATGAGCCAGTGGAAGCAGGAAGGCGATGACGAGCAGGCGGTACGCAGCATTCTCGGTCGTTTGCTGTT
CAGCCAGGACGACATCAAAAAGCCAGCTAAAGTGCTTTCCGGTGGGGAAAAAGGGCGGATGCTGTTTGGTAAGTTAATGA
TGCAGAAGCCGAACATTCTGATCATGGACGAACCGACCAACCACCTGGATATGGAATCCATTGAGTCGCTGAACATGGCA
CTGGAACTGTATCAGGGCACGCTGATCTTTGTTTCTCACGACCGTGAGTTTGTAAGCTCCCTGGCGACCCGTATTCTGGA
AATCACCCCGGAACGCGTGATCGACTTTAGCGGTAATTATGAAGATTACCTGCGTAGTAAAGGGATCGAGTAA

Upstream 100 bases:

>100_bases
TGCCTTTGGCTTGAGTGTAGACCTTAAGCGAGGAGCAGGATCTTCTTTCAGACTTATGGCATAATGCGCGGTTTGTCATA
TCTCTTTTCAGGATACGCCT

Downstream 100 bases:

>100_bases
GTTATTATCAGTAGCCCTGATATGGTCAGGGCTACTGAAACTGATGACAAATGTAAAATTGCCTGATGCGCTACGCTTAT
CAGGCCTTGTATTATCCCTC

Product: ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MLVSSNVTMQFGSKPLFENISVKFGGGNRYGLIGANGSGKSTFMKILGGDLEPTLGNVSLDPNERIGKLRQDQFAFEEFT
VLDTVIMGHKELWEVKQERDRIYALPEMSEEDGYKVADLEVKYGEMDGYSAEARAGELLLGVGIPVEQHYGPMSEVAPGW
KLRVLLAQALFADPDILLLDEPTNNLDIDTIRWLEQVLNERDSTMIIISHDRHFLNMVCTHMADLDYGELRVYPGNYDEY
MTAATQARERLLADNAKKKAQIAELQSFVSRFSANASKSRQATSRARQIDKIKLEEVKASSRQNPFIRFEQDKKLFRNAL
EVEGLTKGFDNGPLFKNLNLLLEVGEKLAVLGTNGVGKSTLLKTLVGDLQPDSGTVKWSENARIGYYAQDHEYEFENDLT
VFEWMSQWKQEGDDEQAVRSILGRLLFSQDDIKKPAKVLSGGEKGRMLFGKLMMQKPNILIMDEPTNHLDMESIESLNMA
LELYQGTLIFVSHDREFVSSLATRILEITPERVIDFSGNYEDYLRSKGIE

Sequences:

>Translated_530_residues
MLVSSNVTMQFGSKPLFENISVKFGGGNRYGLIGANGSGKSTFMKILGGDLEPTLGNVSLDPNERIGKLRQDQFAFEEFT
VLDTVIMGHKELWEVKQERDRIYALPEMSEEDGYKVADLEVKYGEMDGYSAEARAGELLLGVGIPVEQHYGPMSEVAPGW
KLRVLLAQALFADPDILLLDEPTNNLDIDTIRWLEQVLNERDSTMIIISHDRHFLNMVCTHMADLDYGELRVYPGNYDEY
MTAATQARERLLADNAKKKAQIAELQSFVSRFSANASKSRQATSRARQIDKIKLEEVKASSRQNPFIRFEQDKKLFRNAL
EVEGLTKGFDNGPLFKNLNLLLEVGEKLAVLGTNGVGKSTLLKTLVGDLQPDSGTVKWSENARIGYYAQDHEYEFENDLT
VFEWMSQWKQEGDDEQAVRSILGRLLFSQDDIKKPAKVLSGGEKGRMLFGKLMMQKPNILIMDEPTNHLDMESIESLNMA
LELYQGTLIFVSHDREFVSSLATRILEITPERVIDFSGNYEDYLRSKGIE
>Mature_530_residues
MLVSSNVTMQFGSKPLFENISVKFGGGNRYGLIGANGSGKSTFMKILGGDLEPTLGNVSLDPNERIGKLRQDQFAFEEFT
VLDTVIMGHKELWEVKQERDRIYALPEMSEEDGYKVADLEVKYGEMDGYSAEARAGELLLGVGIPVEQHYGPMSEVAPGW
KLRVLLAQALFADPDILLLDEPTNNLDIDTIRWLEQVLNERDSTMIIISHDRHFLNMVCTHMADLDYGELRVYPGNYDEY
MTAATQARERLLADNAKKKAQIAELQSFVSRFSANASKSRQATSRARQIDKIKLEEVKASSRQNPFIRFEQDKKLFRNAL
EVEGLTKGFDNGPLFKNLNLLLEVGEKLAVLGTNGVGKSTLLKTLVGDLQPDSGTVKWSENARIGYYAQDHEYEFENDLT
VFEWMSQWKQEGDDEQAVRSILGRLLFSQDDIKKPAKVLSGGEKGRMLFGKLMMQKPNILIMDEPTNHLDMESIESLNMA
LELYQGTLIFVSHDREFVSSLATRILEITPERVIDFSGNYEDYLRSKGIE

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains

Homologues:

Organism=Homo sapiens, GI148612853, Length=527, Percent_Identity=32.4478178368121, Blast_Score=269, Evalue=5e-72,
Organism=Homo sapiens, GI27881506, Length=536, Percent_Identity=30.5970149253731, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI10947137, Length=536, Percent_Identity=30.5970149253731, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI69354671, Length=529, Percent_Identity=31.3799621928166, Blast_Score=220, Evalue=3e-57,
Organism=Homo sapiens, GI10947135, Length=529, Percent_Identity=31.3799621928166, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI6005701, Length=207, Percent_Identity=27.0531400966184, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1787041, Length=530, Percent_Identity=100, Blast_Score=1088, Evalue=0.0,
Organism=Escherichia coli, GI1789751, Length=529, Percent_Identity=33.0812854442344, Blast_Score=297, Evalue=9e-82,
Organism=Escherichia coli, GI1787182, Length=501, Percent_Identity=32.9341317365269, Blast_Score=246, Evalue=4e-66,
Organism=Escherichia coli, GI2367384, Length=518, Percent_Identity=30.6949806949807, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1786975, Length=526, Percent_Identity=23.1939163498099, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788165, Length=207, Percent_Identity=29.951690821256, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787029, Length=242, Percent_Identity=27.6859504132231, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1788225, Length=227, Percent_Identity=26.431718061674, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1786398, Length=247, Percent_Identity=28.7449392712551, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081791, Length=212, Percent_Identity=27.8301886792453, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788761, Length=213, Percent_Identity=25.3521126760563, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081834, Length=219, Percent_Identity=26.4840182648402, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1786345, Length=253, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081709, Length=219, Percent_Identity=28.7671232876712, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787758, Length=182, Percent_Identity=25.8241758241758, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI87082064, Length=205, Percent_Identity=28.780487804878, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1789891, Length=220, Percent_Identity=24.0909090909091, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790739, Length=199, Percent_Identity=27.6381909547739, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790467, Length=223, Percent_Identity=27.3542600896861, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788897, Length=196, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786803, Length=220, Percent_Identity=26.8181818181818, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786563, Length=216, Percent_Identity=26.3888888888889, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI87082267, Length=208, Percent_Identity=27.4038461538462, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786872, Length=240, Percent_Identity=27.0833333333333, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1790525, Length=224, Percent_Identity=24.5535714285714, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI48994943, Length=226, Percent_Identity=28.7610619469027, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1786703, Length=208, Percent_Identity=29.3269230769231, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1786698, Length=199, Percent_Identity=26.1306532663317, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17555318, Length=537, Percent_Identity=30.5400372439479, Blast_Score=262, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI17553372, Length=536, Percent_Identity=31.7164179104478, Blast_Score=246, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI17559834, Length=539, Percent_Identity=28.2003710575139, Blast_Score=233, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6320874, Length=529, Percent_Identity=31.3799621928166, Blast_Score=261, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6321121, Length=532, Percent_Identity=31.390977443609, Blast_Score=247, Evalue=3e-66,
Organism=Saccharomyces cerevisiae, GI6325030, Length=422, Percent_Identity=28.6729857819905, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324314, Length=421, Percent_Identity=26.8408551068884, Blast_Score=132, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6323278, Length=420, Percent_Identity=27.3809523809524, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24642252, Length=536, Percent_Identity=31.9029850746269, Blast_Score=269, Evalue=4e-72,
Organism=Drosophila melanogaster, GI18859989, Length=536, Percent_Identity=31.9029850746269, Blast_Score=269, Evalue=4e-72,
Organism=Drosophila melanogaster, GI24666836, Length=527, Percent_Identity=30.550284629981, Blast_Score=258, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24641342, Length=543, Percent_Identity=30.2025782688766, Blast_Score=240, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YBIT_ECO57 (P0A9U5)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   A90741
- PIR:   D85591
- RefSeq:   NP_286584.1
- RefSeq:   NP_308924.1
- ProteinModelPortal:   P0A9U5
- PRIDE:   P0A9U5
- EnsemblBacteria:   EBESCT00000024882
- EnsemblBacteria:   EBESCT00000055390
- GeneID:   917637
- GeneID:   958094
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z1042
- KEGG:   ecs:ECs0897
- GeneTree:   EBGT00050000008245
- HOGENOM:   HBG758042
- OMA:   TILTARN
- ProtClustDB:   PRK15064
- BioCyc:   ECOL83334:ECS0897-MONOMER
- GO:   GO:0006810
- InterPro:   IPR003439
- InterPro:   IPR003593
- SMART:   SM00382

Pfam domain/function: PF00005 ABC_tran

EC number: NA

Molecular weight: Translated: 59859; Mature: 59859

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVSSNVTMQFGSKPLFENISVKFGGGNRYGLIGANGSGKSTFMKILGGDLEPTLGNVSL
CEECCCCEEECCCCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCC
DPNERIGKLRQDQFAFEEFTVLDTVIMGHKELWEVKQERDRIYALPEMSEEDGYKVADLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEECCCCCCCCCCEEEEEE
VKYGEMDGYSAEARAGELLLGVGIPVEQHYGPMSEVAPGWKLRVLLAQALFADPDILLLD
EEECCCCCCCCCCCCCCEEEECCCCHHHHCCCHHHCCCCHHHHHHHHHHHHCCCCEEEEE
EPTNNLDIDTIRWLEQVLNERDSTMIIISHDRHFLNMVCTHMADLDYGELRVYPGNYDEY
CCCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEECCCHHHH
MTAATQARERLLADNAKKKAQIAELQSFVSRFSANASKSRQATSRARQIDKIKLEEVKAS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
SRQNPFIRFEQDKKLFRNALEVEGLTKGFDNGPLFKNLNLLLEVGEKLAVLGTNGVGKST
CCCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHH
LLKTLVGDLQPDSGTVKWSENARIGYYAQDHEYEFENDLTVFEWMSQWKQEGDDEQAVRS
HHHHHHHCCCCCCCCEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
ILGRLLFSQDDIKKPAKVLSGGEKGRMLFGKLMMQKPNILIMDEPTNHLDMESIESLNMA
HHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHH
LELYQGTLIFVSHDREFVSSLATRILEITPERVIDFSGNYEDYLRSKGIE
HHHHCCEEEEEECCHHHHHHHHHHHHHCCHHHEEECCCCHHHHHHHCCCC
>Mature Secondary Structure
MLVSSNVTMQFGSKPLFENISVKFGGGNRYGLIGANGSGKSTFMKILGGDLEPTLGNVSL
CEECCCCEEECCCCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCC
DPNERIGKLRQDQFAFEEFTVLDTVIMGHKELWEVKQERDRIYALPEMSEEDGYKVADLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEECCCCCCCCCCEEEEEE
VKYGEMDGYSAEARAGELLLGVGIPVEQHYGPMSEVAPGWKLRVLLAQALFADPDILLLD
EEECCCCCCCCCCCCCCEEEECCCCHHHHCCCHHHCCCCHHHHHHHHHHHHCCCCEEEEE
EPTNNLDIDTIRWLEQVLNERDSTMIIISHDRHFLNMVCTHMADLDYGELRVYPGNYDEY
CCCCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEECCCHHHH
MTAATQARERLLADNAKKKAQIAELQSFVSRFSANASKSRQATSRARQIDKIKLEEVKAS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHC
SRQNPFIRFEQDKKLFRNALEVEGLTKGFDNGPLFKNLNLLLEVGEKLAVLGTNGVGKST
CCCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHH
LLKTLVGDLQPDSGTVKWSENARIGYYAQDHEYEFENDLTVFEWMSQWKQEGDDEQAVRS
HHHHHHHCCCCCCCCEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
ILGRLLFSQDDIKKPAKVLSGGEKGRMLFGKLMMQKPNILIMDEPTNHLDMESIESLNMA
HHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHH
LELYQGTLIFVSHDREFVSSLATRILEITPERVIDFSGNYEDYLRSKGIE
HHHHCCEEEEEECCHHHHHHHHHHHHHCCHHHEEECCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796