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The map label for this gene is ybhS

Identifier: 157160268

GI number: 157160268

Start: 852723

End: 853856

Strand: Reverse

Name: ybhS

Synonym: EcHS_A0847

Alternate gene names: 157160268

Gene position: 853856-852723 (Counterclockwise)

Preceding gene: 157160269

Following gene: 157160267

Centisome position: 18.39

GC content: 54.94

Gene sequence:

>1134_bases
ATGAGTAACCCGATTCTGTCCTGGCGTCGCGTACGGGCGCTGTGCGTTAAAGAGACGCGGCAGATCGTTCGCGATCCGAG
TAGCTGGCTGATTGCGGTAGTGATCCCGCTGCTACTGCTGTTTATTTTTGGTTACGGCATTAACCTCGACTCCAGCAAGC
TGCGGGTCGGGATTTTACTGGAACAGCGTAGCGAAGCGGCGCTGGATTTCACCCACACCATGACCGGTTCACCCTACATC
GACGCCACCATCAGCGATAACCGTCAGGAACTGATCGCCAAAATGCAGGCGGGGAAAATTCGCGGTCTGGTGGTTATTCC
GGTGGATTTTGCGGAACAGATGGAGCGCGCCAACGCCACCGCACCGATTCAGGTGATCACCGACGGCAGTGAGCCGAATA
CCGCTAACTTTGTACAGGGGTATGTCGAAGGGATCTGGCAGATCTGGCAAATGCAGCGAGCGGAGGACAACGGGCAGACT
TTTGAACCGCTTATTGATGTACAAACCCGCTACTGGTTTAACCCGGCGGCGATAAGCCAGCACTTTATTATCCCGGGTGC
GGTGACCATTATCATGACGGTCATCGGCGCGATTCTCACCTCGCTGGTGGTGGCGCGAGAATGGGAACGCGGCACCATGG
AGGCTCTGCTCTCTACGGAGATTACCCGCACGGAACTGCTGCTGTGTAAGCTGATCCCTTATTACTTTCTCGGGATGCTG
GCGATGCTGCTGTGTATGCTGGTGTCAGTGTTTATTCTCGGCGTGCCGTATCGCGGTTCGCTGCTTATTCTGTTTTTTAT
CTCCAGCCTGTTTTTACTCAGTACCCTGGGGATGGGGCTGCTGATTTCCACGATTACCCGCAACCAGTTCAATGCCGCTC
AGGTCGCCCTGAACGCCGCGTTCCTGCCGTCGATTATGCTTTCCGGCTTTATTTTTCAGATCGACAGTATGCCCGCGGTG
ATCCGCGCGGTGACGTACATTATTCCCGCTCGTTATTTCGTCAGCACCCTGCAAAGCCTGTTCCTCGCCGGGAATATTCC
AGTGGTGCTGGTGGTAAACGTGCTGTTTTTGATCGCTTCGGCGGTGATGTTTATCGGCCTGACGTGGCTGAAAACCAAAC
GTCGGCTGGATTAG

Upstream 100 bases:

>100_bases
GATGATTTGAAAGCGCAGTCGGCCAACGACGAGCAACCCGATCCCACCATGGAGCAAGCCTTTATTCAGTTGATCCACGA
CTGGGATAAGGAGCATAGCA

Downstream 100 bases:

>100_bases
GGAGAAGAGCATGTTTCATCGCTTATGGACGTTAATCCGCAAAGAGTTGCAGTCGTTGCTGCGCGAACCACAAACCCGCG
CGATTCTGATTTTACCTGTG

Product: ABC-2 type transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MSNPILSWRRVRALCVKETRQIVRDPSSWLIAVVIPLLLLFIFGYGINLDSSKLRVGILLEQRSEAALDFTHTMTGSPYI
DATISDNRQELIAKMQAGKIRGLVVIPVDFAEQMERANATAPIQVITDGSEPNTANFVQGYVEGIWQIWQMQRAEDNGQT
FEPLIDVQTRYWFNPAAISQHFIIPGAVTIIMTVIGAILTSLVVAREWERGTMEALLSTEITRTELLLCKLIPYYFLGML
AMLLCMLVSVFILGVPYRGSLLILFFISSLFLLSTLGMGLLISTITRNQFNAAQVALNAAFLPSIMLSGFIFQIDSMPAV
IRAVTYIIPARYFVSTLQSLFLAGNIPVVLVVNVLFLIASAVMFIGLTWLKTKRRLD

Sequences:

>Translated_377_residues
MSNPILSWRRVRALCVKETRQIVRDPSSWLIAVVIPLLLLFIFGYGINLDSSKLRVGILLEQRSEAALDFTHTMTGSPYI
DATISDNRQELIAKMQAGKIRGLVVIPVDFAEQMERANATAPIQVITDGSEPNTANFVQGYVEGIWQIWQMQRAEDNGQT
FEPLIDVQTRYWFNPAAISQHFIIPGAVTIIMTVIGAILTSLVVAREWERGTMEALLSTEITRTELLLCKLIPYYFLGML
AMLLCMLVSVFILGVPYRGSLLILFFISSLFLLSTLGMGLLISTITRNQFNAAQVALNAAFLPSIMLSGFIFQIDSMPAV
IRAVTYIIPARYFVSTLQSLFLAGNIPVVLVVNVLFLIASAVMFIGLTWLKTKRRLD
>Mature_376_residues
SNPILSWRRVRALCVKETRQIVRDPSSWLIAVVIPLLLLFIFGYGINLDSSKLRVGILLEQRSEAALDFTHTMTGSPYID
ATISDNRQELIAKMQAGKIRGLVVIPVDFAEQMERANATAPIQVITDGSEPNTANFVQGYVEGIWQIWQMQRAEDNGQTF
EPLIDVQTRYWFNPAAISQHFIIPGAVTIIMTVIGAILTSLVVAREWERGTMEALLSTEITRTELLLCKLIPYYFLGMLA
MLLCMLVSVFILGVPYRGSLLILFFISSLFLLSTLGMGLLISTITRNQFNAAQVALNAAFLPSIMLSGFIFQIDSMPAVI
RAVTYIIPARYFVSTLQSLFLAGNIPVVLVVNVLFLIASAVMFIGLTWLKTKRRLD

Specific function: Unknown

COG id: COG0842

COG function: function code V; ABC-type multidrug transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-2 domain

Homologues:

Organism=Escherichia coli, GI1787011, Length=377, Percent_Identity=100, Blast_Score=759, Evalue=0.0,
Organism=Escherichia coli, GI48994943, Length=338, Percent_Identity=31.6568047337278, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1787010, Length=335, Percent_Identity=26.5671641791045, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI226510979, Length=265, Percent_Identity=28.3018867924528, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YBHS_ECO57 (P0AFQ4)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   G90737
- PIR:   H85587
- RefSeq:   NP_286556.1
- RefSeq:   NP_308898.1
- ProteinModelPortal:   P0AFQ4
- EnsemblBacteria:   EBESCT00000027560
- EnsemblBacteria:   EBESCT00000055204
- GeneID:   917608
- GeneID:   958017
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z1013
- KEGG:   ecs:ECs0871
- GeneTree:   EBGT00050000008883
- HOGENOM:   HBG471594
- OMA:   EPRYWFN
- ProtClustDB:   CLSK879769
- BioCyc:   ECOL83334:ECS0871-MONOMER
- InterPro:   IPR000412
- InterPro:   IPR013525

Pfam domain/function: PF01061 ABC2_membrane

EC number: NA

Molecular weight: Translated: 42061; Mature: 41929

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS51012 ABC_TM2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x13634d0c)-; HASH(0x1353c008)-; HASH(0x118399a8)-; HASH(0x1189bac4)-; HASH(0x13792f54)-; HASH(0x1249215c)-; HASH(0x13730ad8)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPILSWRRVRALCVKETRQIVRDPSSWLIAVVIPLLLLFIFGYGINLDSSKLRVGILL
CCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
EQRSEAALDFTHTMTGSPYIDATISDNRQELIAKMQAGKIRGLVVIPVDFAEQMERANAT
ECCCCHHHEEHEECCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEEECCHHHHHHHCCCC
APIQVITDGSEPNTANFVQGYVEGIWQIWQMQRAEDNGQTFEPLIDVQTRYWFNPAAISQ
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEECHHHHCC
HFIIPGAVTIIMTVIGAILTSLVVAREWERGTMEALLSTEITRTELLLCKLIPYYFLGML
CEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLLCMLVSVFILGVPYRGSLLILFFISSLFLLSTLGMGLLISTITRNQFNAAQVALNAA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
FLPSIMLSGFIFQIDSMPAVIRAVTYIIPARYFVSTLQSLFLAGNIPVVLVVNVLFLIAS
HHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AVMFIGLTWLKTKRRLD
HHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
SNPILSWRRVRALCVKETRQIVRDPSSWLIAVVIPLLLLFIFGYGINLDSSKLRVGILL
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
EQRSEAALDFTHTMTGSPYIDATISDNRQELIAKMQAGKIRGLVVIPVDFAEQMERANAT
ECCCCHHHEEHEECCCCCEEEEEECCCHHHHHHHHHCCCCCCEEEEECCHHHHHHHCCCC
APIQVITDGSEPNTANFVQGYVEGIWQIWQMQRAEDNGQTFEPLIDVQTRYWFNPAAISQ
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEECHHHHCC
HFIIPGAVTIIMTVIGAILTSLVVAREWERGTMEALLSTEITRTELLLCKLIPYYFLGML
CEECHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLLCMLVSVFILGVPYRGSLLILFFISSLFLLSTLGMGLLISTITRNQFNAAQVALNAA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
FLPSIMLSGFIFQIDSMPAVIRAVTYIIPARYFVSTLQSLFLAGNIPVVLVVNVLFLIAS
HHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AVMFIGLTWLKTKRRLD
HHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796