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The map label for this gene is ybhJ [H]

Identifier: 157160246

GI number: 157160246

Start: 830082

End: 832367

Strand: Direct

Name: ybhJ [H]

Synonym: EcHS_A0825

Alternate gene names: 157160246

Gene position: 830082-832367 (Clockwise)

Preceding gene: 157160245

Following gene: 157160250

Centisome position: 17.88

GC content: 51.27

Gene sequence:

>2286_bases
GTGCGCAGATATCTGGAGCATCTGATGATCAAGTTATCTGAAAAAGGCGTGTTTCTCGCCAGTAATAACGAAATAATTGC
CGAAGAACATTTCACCGGCGAAATTAAAAAAGAAGAAGCCAAAAAAGGCACTATTGCCTGGTCTATTCTCTCTTCTCATA
ATACGTCCGGAAATATGGATAAACTTAAAATTAAGTTTGATTCATTAGCCTCTCACGATATTACCTTTGTTGGTATTGTA
CAGACCGCTAAAGCGTCCGGAATGGAACGTTTCCCGCTGCCGTATGTGCTGACCAACTGCCATAACTCACTCTGCGCCGT
CGGCGGCACCATTAACGGTGATGACCATGTTTTTGGTTTATCGGCAGCTCAGCGTTATGGCGGTATTTTTGTGCCTCCGC
ATATTGCGGTCATCCATCAATATATGCGTGAGATGATGGCAGGCGGCGGCAAAATGATCCTCGGGTCAGACAGCCACACC
CGTTACGGTGCATTAGGGACAATGGCAGTCGGTGAGGGCGGCGGTGAGTTGGTAAAACAGCTGCTTAATGACACCTGGGA
TATCGACTATCCGGGAGTTGTTGCGGTGCATCTGACCGGAAAACCAGCGCCGTATGTGGGGCCGCAGGATGTGGCGCTGG
CTATCATCGGTGCCGTGTTCAAAAACGGCTACGTCAAAAACAAAGTGATGGAATTCGTAGGTCCCGGTGTTGCTGCGCTC
TCTACCGATTTCCGTAACAGCGTTGACGTTATGACCACTGAAACGACCTGTTTAAGTTCTGTCTGGCAAACCGATGAAGA
AGTCCATAACTGGCTGGCGCTGCACGGTCGCGGCCAGGATTACTGCCAGCTTAACCCTCAACCGATGGCGTACTACGATG
GCTGCATCAGCGTTGATTTAAGCGCCATCAAACCAATGATTGCGCTGCCGTTCCACCCGAGCAACGTGTATGAAATCGAC
ACACTGAACCAGAACCTGACCGACATTCTGCGTGAGATTGAAATTGAGTCCGAACGCGTGGCGCACGGTAAAGCCAAACT
CTCGCTGCTGGATAAAGTGGAAAATGGTCGCCTGAAAGTGCAGCAGGGGATTATCGCGGGCTGTTCTGGCGGTAACTACG
AAAACGTCATCGCGGCGGCGAATGCACTGCGCGGTCAATCCTGTGGCAATGACACCTTCTCGCTGGCAGTTTACCCGTCA
TCACAGCCGGTGTTTATGGATCTCGCCAAAAAAGGTGTGGTAGCAGATTTGATTGGCGCAGGCGCAATCATCAGAACCGC
GTTCTGCGGCCCATGCTTTGGCGCGGGCGATACGCCAATCAACAACGGATTAAGTATTCGCCACACCACGCGCAACTTCC
CAAACCGCGAAGGCTCTAAGCCAGCTAATGGGCAGATGTCAGCGGTGGCGTTGATGGACGCTCGTTCTATCGCTGCGACT
GCGGCAAACGGTGGCTATTTAACCTCTGCCAGCGAACTTGATTGCTGGGACAACGTGCCGGAGTACGCCTTCGATGTAAC
GCCGTATAAAAACCGTGTTTATCAGGGCTTTGTGAAAGGGGCAACTCAGCAACCGCTGATTTACGGACCGAACATTAAAG
ACTGGCCGGAATTGGGTGCGCTGACTGACAATATCGTCCTGAAAGTGTGCTCGAAGATCCTCGACGAAGTGACCACCACC
GACGAACTGATTCCTTCCGGTGAAACCTCTTCTTATCGTTCAAATCCGATTGGTCTGGCGGAGTTTACCCTGTCACGCCG
CGATCCCGGTTATGTTGGCAGAAGTAAAGCGACTGCTGAGCTGGAAAATCAGCGTCTGGCGGGGAATGTCAGCGAGCTGA
CAGAGGTGTTTGCGCGCATTAAGCAGATTGCTGGTCAGGAGCATATTGATCCGCTGCAAACTGAAATTGGCAGCATGGTA
TATGCGGTGAAACCAGGCGATGGTTCTGCGCGTGAACAGGCGGCGAGCTGCCAGCGTGTGATTGGCGGTCTGGCGAATAT
TGCCGAAGAGTACGCGACTAAACGCTACCGTTCTAACGTCATCAACTGGGGGATGTTACCGCTGCAGATGGCGGAAGTGC
CAACCTTTGAAGTGGGGGATTACATTTACATCCCTGGCATTAAAGCGGCGCTGGATAATCCGGGTACGACGTTTAAAGGT
TATGTGATCCATGAAGATGCGCCGGTAACGGAAATTACGCTCTATATGGAAAGTCTGACTGCTGAAGAGCGCGAGATTAT
CAAGGCGGGTAGTTTGATTAACTTCAATAAAAACCGTCAGATGTAA

Upstream 100 bases:

>100_bases
CTTACTTATGTAAGCTCCTGGGGATTCACTCACTTGTCGCCTTCCTGCAACTCGAATTATTTAGAGTATATCCATTTATT
ATCTTTCTGCGCACTTCACG

Downstream 100 bases:

>100_bases
AAAGCGCCATGTGAATGTAGGTCGCATTCGGCACTTATTGTCGGATGCGATGCTTGCGCATCTTATCCGACCTACGAATC
GCATCGAATCTGTAGGCCAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 761; Mature: 761

Protein sequence:

>761_residues
MRRYLEHLMIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSSHNTSGNMDKLKIKFDSLASHDITFVGIV
QTAKASGMERFPLPYVLTNCHNSLCAVGGTINGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHT
RYGALGTMAVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVKNKVMEFVGPGVAAL
STDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQLNPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEID
TLNQNLTDILREIEIESERVAHGKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPS
SQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREGSKPANGQMSAVALMDARSIAAT
AANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQGFVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTT
DELIPSGETSSYRSNPIGLAEFTLSRRDPGYVGRSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPLQTEIGSMV
YAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQMAEVPTFEVGDYIYIPGIKAALDNPGTTFKG
YVIHEDAPVTEITLYMESLTAEEREIIKAGSLINFNKNRQM

Sequences:

>Translated_761_residues
MRRYLEHLMIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSSHNTSGNMDKLKIKFDSLASHDITFVGIV
QTAKASGMERFPLPYVLTNCHNSLCAVGGTINGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHT
RYGALGTMAVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVKNKVMEFVGPGVAAL
STDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQLNPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEID
TLNQNLTDILREIEIESERVAHGKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPS
SQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREGSKPANGQMSAVALMDARSIAAT
AANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQGFVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTT
DELIPSGETSSYRSNPIGLAEFTLSRRDPGYVGRSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPLQTEIGSMV
YAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQMAEVPTFEVGDYIYIPGIKAALDNPGTTFKG
YVIHEDAPVTEITLYMESLTAEEREIIKAGSLINFNKNRQM
>Mature_761_residues
MRRYLEHLMIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSSHNTSGNMDKLKIKFDSLASHDITFVGIV
QTAKASGMERFPLPYVLTNCHNSLCAVGGTINGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHT
RYGALGTMAVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVKNKVMEFVGPGVAAL
STDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQLNPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEID
TLNQNLTDILREIEIESERVAHGKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPS
SQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREGSKPANGQMSAVALMDARSIAAT
AANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQGFVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTT
DELIPSGETSSYRSNPIGLAEFTLSRRDPGYVGRSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPLQTEIGSMV
YAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQMAEVPTFEVGDYIYIPGIKAALDNPGTTFKG
YVIHEDAPVTEITLYMESLTAEEREIIKAGSLINFNKNRQM

Specific function: Unknown

COG id: COG1048

COG function: function code C; Aconitase A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aconitase/IPM isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4501867, Length=745, Percent_Identity=24.8322147651007, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI8659555, Length=401, Percent_Identity=23.4413965087282, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI87081781, Length=753, Percent_Identity=99.734395750332, Blast_Score=1559, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25149337, Length=742, Percent_Identity=23.8544474393531, Blast_Score=117, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI32564738, Length=719, Percent_Identity=23.9221140472879, Blast_Score=113, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI25149342, Length=609, Percent_Identity=23.1527093596059, Blast_Score=93, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17568399, Length=659, Percent_Identity=22.6100151745068, Blast_Score=78, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323335, Length=741, Percent_Identity=23.7516869095816, Blast_Score=137, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6322261, Length=395, Percent_Identity=25.8227848101266, Blast_Score=115, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6320440, Length=405, Percent_Identity=25.1851851851852, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321429, Length=333, Percent_Identity=24.9249249249249, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI28571643, Length=685, Percent_Identity=24.6715328467153, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281365315, Length=705, Percent_Identity=22.6950354609929, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17864292, Length=705, Percent_Identity=22.6950354609929, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI161076999, Length=657, Percent_Identity=22.6788432267884, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015931
- InterPro:   IPR015937
- InterPro:   IPR001030
- InterPro:   IPR015928
- InterPro:   IPR015932
- InterPro:   IPR015935
- InterPro:   IPR000573 [H]

Pfam domain/function: PF00330 Aconitase; PF00694 Aconitase_C [H]

EC number: NA

Molecular weight: Translated: 82559; Mature: 82559

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRYLEHLMIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSSHNTSGNMD
CHHHHHHHHHEECCCCEEEECCCCEEEECCCCCCHHHHHCCCCCEEEEEEECCCCCCCCE
KLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGTINGDDHVFGL
EEEEEECCCCCCCEEEEEEEEHHHHCCCCCCCCCHHHHHCCCCCEEECCCCCCCCCEEEC
SAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTMAVGEGGGELVKQ
HHHHHCCCEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEECCCHHHHHHH
LLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVKNKVMEFVGPGVAAL
HHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHH
STDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQLNPQPMAYYDGCISVDL
HHHHCCCCEEEEECHHHHHHHHCCHHHHHHEEEECCCCCCCEEECCCCCEEECCEEEEEH
SAIKPMIALPFHPSNVYEIDTLNQNLTDILREIEIESERVAHGKAKLSLLDKVENGRLKV
HHCCCEEEECCCCCCEEEEECCCCHHHHHHHHHHCCHHHHHCCHHHHHHHHHCCCCCEEE
QQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPSSQPVFMDLAKKGVVADLIGA
ECCEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHCCHHHHHHHC
GAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREGSKPANGQMSAVALMDARSIAAT
CHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEHHHHHHEE
AANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQGFVKGATQQPLIYGPNIKDWPELGA
CCCCCEECCCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCEEECCCCCCCHHHCC
LTDNIVLKVCSKILDEVTTTDELIPSGETSSYRSNPIGLAEFTLSRRDPGYVGRSKATAE
HHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHH
LENQRLAGNVSELTEVFARIKQIAGQEHIDPLQTEIGSMVYAVKPGDGSAREQAASCQRV
HHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEEEEECCCCCHHHHHHHHHHH
IGGLANIAEEYATKRYRSNVINWGMLPLQMAEVPTFEVGDYIYIPGIKAALDNPGTTFKG
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHCCCCEECCCEEEECCCHHHCCCCCCEEEE
YVIHEDAPVTEITLYMESLTAEEREIIKAGSLINFNKNRQM
EEEECCCCCCCEEHHHHHHHHHHHHHHHHCCEEECCCCCCC
>Mature Secondary Structure
MRRYLEHLMIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSSHNTSGNMD
CHHHHHHHHHEECCCCEEEECCCCEEEECCCCCCHHHHHCCCCCEEEEEEECCCCCCCCE
KLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGTINGDDHVFGL
EEEEEECCCCCCCEEEEEEEEHHHHCCCCCCCCCHHHHHCCCCCEEECCCCCCCCCEEEC
SAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTMAVGEGGGELVKQ
HHHHHCCCEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEECCCHHHHHHH
LLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVKNKVMEFVGPGVAAL
HHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHH
STDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQLNPQPMAYYDGCISVDL
HHHHCCCCEEEEECHHHHHHHHCCHHHHHHEEEECCCCCCCEEECCCCCEEECCEEEEEH
SAIKPMIALPFHPSNVYEIDTLNQNLTDILREIEIESERVAHGKAKLSLLDKVENGRLKV
HHCCCEEEECCCCCCEEEEECCCCHHHHHHHHHHCCHHHHHCCHHHHHHHHHCCCCCEEE
QQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPSSQPVFMDLAKKGVVADLIGA
ECCEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHCCHHHHHHHC
GAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREGSKPANGQMSAVALMDARSIAAT
CHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEHHHHHHEE
AANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQGFVKGATQQPLIYGPNIKDWPELGA
CCCCCEECCCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCEEECCCCCCCHHHCC
LTDNIVLKVCSKILDEVTTTDELIPSGETSSYRSNPIGLAEFTLSRRDPGYVGRSKATAE
HHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHH
LENQRLAGNVSELTEVFARIKQIAGQEHIDPLQTEIGSMVYAVKPGDGSAREQAASCQRV
HHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEEEEECCCCCHHHHHHHHHHH
IGGLANIAEEYATKRYRSNVINWGMLPLQMAEVPTFEVGDYIYIPGIKAALDNPGTTFKG
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHCCCCEECCCEEEECCCHHHCCCCCCEEEE
YVIHEDAPVTEITLYMESLTAEEREIIKAGSLINFNKNRQM
EEEECCCCCCCEEHHHHHHHHHHHHHHHHCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]