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The map label for this gene is ybhA

Identifier: 157160241

GI number: 157160241

Start: 824216

End: 825034

Strand: Reverse

Name: ybhA

Synonym: EcHS_A0820

Alternate gene names: 157160241

Gene position: 825034-824216 (Counterclockwise)

Preceding gene: 157160243

Following gene: 157160236

Centisome position: 17.77

GC content: 51.28

Gene sequence:

>819_bases
ATGACCACACGCGTGATTGCTCTCGACTTAGACGGCACCTTATTGACCCCGAAAAAGACCCTGCTTCCTTCATCGATAGA
AGCCCTGGCCCGCGCTCGCGAAGCAGGCTATCAATTAATCATCGTCACAGGTCGCCATCACGTCGCTATTCATCCTTTTT
ATCAGGCGCTGGCGCTGGATACACCTGCTATTTGCTGTAATGGCACCTATTTGTATGATTATCATGCAAAAACCGTGCTG
GAAGCGGACCCAATGCCCGTTATTAAAGCCCTGCAACTCATTGAGATGCTGAATGAACACCACATTCACGGTCTGATGTA
TGTCGATGATGCAATGGTCTATGAGCACCCGACCGGGCATGTCATTCGCACATCTAACTGGGCGCAAACCCTGCCGCCGG
AACAGCGTCCGACTTTCACACAAGTCGCTTCTCTGGCTGAAACGGCGCAACAAGTTAACGCCGTATGGAAGTTCGCCCTG
ACGCACGATGACCTGCCGCAATTGCAGCATTTTGGTAAGCATGTCGAACATGAACTAGGACTGGAGTGTGAATGGTCCTG
GCACGATCAGGTTGATATTGCACGCGGCGGCAACAGCAAAGGTAAACGTTTGACGAAATGGGTTGAGGCGCAAGGTTGGT
CGATGGAAAACGTCGTGGCATTCGGCGATAACTTTAATGATATCAGTATGCTGGAAGCCGCTGGTACAGGCGTGGCGATG
GGCAACGCCGATGACGCGGTAAAAGCGCGCGCCAACATTGTGATTGGTGATAACACCACCGACAGCATTGCCCAATTCAT
TTATAGCCACCTGATTTAA

Upstream 100 bases:

>100_bases
GGCGGTGAATGCTGAATTAAAACGCAGAATTTTGTCCGATAGTGGTATCGGTGTACCATTCGCGCAGACGAAAATTCTTA
ACCTTAATCTGGAATACGCC

Downstream 100 bases:

>100_bases
TCAGGCGGTTATCGACACACTTTTAATTTGCGCGTACAGCCACAGGCCAGGTTTGATCGCCAGTTCATCCCTGGCCCACG
GGCTGATACGCGCCCACAGC

Product: phosphotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVL
EADPMPVIKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFAL
THDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAM
GNADDAVKARANIVIGDNTTDSIAQFIYSHLI

Sequences:

>Translated_272_residues
MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVL
EADPMPVIKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFAL
THDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAM
GNADDAVKARANIVIGDNTTDSIAQFIYSHLI
>Mature_271_residues
TTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLE
ADPMPVIKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALT
HDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAMG
NADDAVKARANIVIGDNTTDSIAQFIYSHLI

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates pyridoxalphosphate and erythrose 4-phosphate

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family

Homologues:

Organism=Escherichia coli, GI1786982, Length=272, Percent_Identity=100, Blast_Score=568, Evalue=1e-163,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YBHA_ECOLI (P21829)

Other databases:

- EMBL:   U27192
- EMBL:   U07867
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   F64812
- RefSeq:   AP_001397.1
- RefSeq:   NP_415287.1
- ProteinModelPortal:   P21829
- SMR:   P21829
- STRING:   P21829
- EnsemblBacteria:   EBESCT00000002252
- EnsemblBacteria:   EBESCT00000016878
- GeneID:   945372
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW0749
- KEGG:   eco:b0766
- EchoBASE:   EB1221
- EcoGene:   EG11239
- eggNOG:   COG0561
- GeneTree:   EBGT00050000009623
- HOGENOM:   HBG728500
- OMA:   TLGLECE
- ProtClustDB:   PRK10530
- BioCyc:   EcoCyc:EG11239-MONOMER
- BioCyc:   MetaCyc:EG11239-MONOMER
- Genevestigator:   P21829
- GO:   GO:0016020
- InterPro:   IPR001757
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR000150
- InterPro:   IPR006380
- Gene3D:   G3DSA:3.40.50.1000
- PANTHER:   PTHR11939
- TIGRFAMs:   TIGR00099
- TIGRFAMs:   TIGR01484

Pfam domain/function: PF00702 Hydrolase; PF05116 S6PP; SSF56784 SSF56784

EC number: NA

Molecular weight: Translated: 30202; Mature: 30070

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS01228 COF_1; PS01229 COF_2

Important sites: ACT_SITE 9-9

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTGRHHVAIHPFYQALALD
CCEEEEEEECCCEEECCHHHHCHHHHHHHHHHHHCCCEEEEEECCCEEEECHHHHHHHCC
TPAICCNGTYLYDYHAKTVLEADPMPVIKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGH
CCCEEECCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCEEEEECCCCC
VIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALTHDDLPQLQHFGKHVEHELG
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCC
LECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAM
CEEEECCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHCCCCEEE
GNADDAVKARANIVIGDNTTDSIAQFIYSHLI
CCCCHHHHEEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTGRHHVAIHPFYQALALD
CEEEEEEECCCEEECCHHHHCHHHHHHHHHHHHCCCEEEEEECCCEEEECHHHHHHHCC
TPAICCNGTYLYDYHAKTVLEADPMPVIKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGH
CCCEEECCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHCCCEEEEEECCEEEEECCCCC
VIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALTHDDLPQLQHFGKHVEHELG
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCC
LECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAM
CEEEECCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHCCCCEEE
GNADDAVKARANIVIGDNTTDSIAQFIYSHLI
CCCCHHHHEEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7665460; 8564363; 8905232; 9278503