Click here to switch to the map view.

The map label for this gene is modB

Identifier: 157160239

GI number: 157160239

Start: 822465

End: 823154

Strand: Direct

Name: modB

Synonym: EcHS_A0818

Alternate gene names: 157160239

Gene position: 822465-823154 (Clockwise)

Preceding gene: 157160238

Following gene: 157160240

Centisome position: 17.71

GC content: 54.06

Gene sequence:

>690_bases
ATGATACTGACCGATCCAGAATGGCAGGCAGTTTTATTAAGCCTGAAAGTTTCTTCCCTGGCTGTGCTGTTTAGCCTGCC
GTTTGGGATCTTTTTTGCCTGGTTACTGGTGCGTTGCACGTTTCCGGGCAAAGCTCTGCTCGACAGCGTACTGCATCTAC
CGCTGGTGTTACCGCCCGTGGTCGTCGGTTACTTATTATTAGTTTCGATGGGACGGCGCGGATTTATCGGTGAACGTCTG
TATGACTGGTTTGGTATTACCTTCGCCTTTAGCTGGCGCGGCGCGGTTCTCGCTGCCGCCGTCATGTCGTTTCCGCTGAT
GGTGCGGGCAATTCGTCTGGCGCTGGAAGGGGTTGATGTCAAACTGGAACAGGCCGCAAGAACACTGGGGGCCGGGCGCT
GGCGCGTTTTCTTTACTATCACGTTACCGCTGACCTTACCGGGAATTATTGTTGGTACGGTACTGGCTTTTGCTCGTTCT
CTCGGTGAGTTTGGTGCAACCATCACCTTTGTGTCGAACATTCCTGGTGAAACGCGAACCATTCCTTCTGCCATGTATAC
CCTGATCCAGACCCCCGGCGGGGAAAGTGGAGCGGCGAGACTGTGCATTATTTCTATTGCGCTGGCGATGATCTCCCTGT
TGATTTCAGAATGGCTGGCCAGAATCAGCCGTGAACGGGCGGGGCGCTAA

Upstream 100 bases:

>100_bases
TGGAAGGGCATAACAATGCGACAGTGAAAGCATTTTATGATTATCTGAAGGGACCGCAGGCAGCGGAAATCTTTAAACGT
TACGGATTTACAATCAAGTA

Downstream 100 bases:

>100_bases
TCATGCTGGAACTGAATTTTTCCCAGACGTTGGGCAACCATTGCCTGACTATTAATGAAACGCTGCCCGCCAATGGCATC
ACTGCTATCTTTGGCGTCTC

Product: molybdate ABC transporter permease protein

Products: ADP; phosphate; MoO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERL
YDWFGITFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARS
LGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR

Sequences:

>Translated_229_residues
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERL
YDWFGITFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARS
LGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR
>Mature_229_residues
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERL
YDWFGITFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARS
LGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR

Specific function: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane

COG id: COG4149

COG function: function code P; ABC-type molybdate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1786980, Length=229, Percent_Identity=100, Blast_Score=445, Evalue=1e-126,
Organism=Escherichia coli, GI1788764, Length=232, Percent_Identity=34.4827586206897, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI87082099, Length=232, Percent_Identity=34.4827586206897, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787369, Length=185, Percent_Identity=30.8108108108108, Blast_Score=71, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MODB_ECO57 (P0AF02)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   A85579
- PIR:   H90727
- RefSeq:   NP_286485.1
- RefSeq:   NP_308819.1
- ProteinModelPortal:   P0AF02
- SMR:   P0AF02
- EnsemblBacteria:   EBESCT00000024082
- EnsemblBacteria:   EBESCT00000057290
- GeneID:   917529
- GeneID:   957911
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z0934
- KEGG:   ecs:ECs0792
- GeneTree:   EBGT00050000008926
- HOGENOM:   HBG685300
- OMA:   QRTASVC
- ProtClustDB:   PRK09421
- BioCyc:   ECOL83334:ECS0792-MONOMER
- InterPro:   IPR000515
- InterPro:   IPR011867
- TIGRFAMs:   TIGR02141

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 24939; Mature: 24939

Theoretical pI: Translated: 10.71; Mature: 10.71

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x403b4f78)-; HASH(0x118ac0a4)-; HASH(0x12c5cac8)-; HASH(0x134c3914)-; HASH(0x133a9420)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VVGYLLLVSMGRRGFIGERLYDWFGITFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
KLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARSLGEFGATITFVSNIPGETRT
HHHHHHHHHCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHH
IPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VVGYLLLVSMGRRGFIGERLYDWFGITFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
KLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARSLGEFGATITFVSNIPGETRT
HHHHHHHHHCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHH
IPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; MoO42- [Periplasm]; H2O [C]

Specific reaction: ATP + MoO42- [Periplasm] + H2O = ADP + phosphate + MoO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796