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The map label for this gene is modF [H]

Identifier: 157160235

GI number: 157160235

Start: 818919

End: 820391

Strand: Reverse

Name: modF [H]

Synonym: EcHS_A0814

Alternate gene names: 157160235

Gene position: 820391-818919 (Counterclockwise)

Preceding gene: 157160236

Following gene: 157160234

Centisome position: 17.67

GC content: 52.68

Gene sequence:

>1473_bases
ATGTCATCGTTGCAAATTTTGCAAGGCACGTTTCGTCTTAGCGACACAAAAACGCTGCAATTGCCTCAGCTAACGTTAAA
CGCGGGTGATAGTTGGGCGTTTGTCGGTTCGAATGGAAGCGGGAAATCGGCCCTGGCCCGCGCGCTGGCGGGGGAACTTC
CGCTTTTGAAAGGTGAACGGCAAAGCCAGTTTTCCCACATCACTCGTCTCTCCTTCGAGCAATTGCAAAAGCTCGTCAGC
GACGAATGGCAACGGAATAACACCGATATGCTCGGCCCTGGCGAAGATGACACCGGACGCACTACGGCTGAGATTATTCA
GGATGAAGTAAAGGATGCACCGCGTTGCATGCAACTGGCGCAGCAGTTCGGTATTACCGCCCTCCTCGACCGACGCTTTA
AATACCTTTCCACTGGCGAGACGCGAAAAACCCTGCTGTGTCAGGCGCTGATGTCGGAGCCTGACTTGTTGATTCTTGAT
GAGCCGTTCGATGGCCTGGATGTTGCTTCACGTCAGCAGCTGGCTGAGCGACTCGCCTCGTTACATCAGTCCGGTATTAC
TCTGGTACTGGTGCTCAATCGCTTCGATGAGATCCCGGAATTTGTCCAGTTTGCTGGCGTGCTGGCGGATTGTACGTTAG
CGGAAACGGGCGCTAAAGAGGAACTGCTCCAGCAAGCACTCGTCGCGCAACTGGCGCATAGCGAACAGCTTGAAGGTGTG
CAACTGCCGGAACCGGATGAACCTTCAGCACGTCACGCCTTACCCGCCAACGAACCGCGCATTGTGCTGAACAATGGCGT
GGTTTCTTATAACGATCGCCCCATTCTTAATAACCTTAGCTGGCAGGTGAATCCAGGCGAACACTGGCAAATTGTCGGGC
CAAATGGTGCGGGAAAATCGACGTTATTAAGCCTGATTACTGGCGATCATCCGCAAGGTTACAGCAACGATTTGACGCTT
TTCGGCCGACGTCGTGGCAGCGGCGAAACCATCTGGGATATCAAAAAGCATATCGGTTACGTCAGCAGTAGTTTGCATCT
GGATTACCGGGTCAGCACTACCGTGCGTAATGTGATTCTTTCTGGCTATTTCGATTCGATTGGCATTTATCAAGCCGTTT
CGGATCGCCAGCAAAAACTGGTGCAGCAGTGGCTGGATATTCTCGGCATTGATAAACGCACGGCTGACGCTCCGTTCCAT
AGTCTTTCCTGGGGACAGCAGCGTCTGGCGCTGATCGTCCGCGCACTGGTGAAACATCCGACGTTGCTTATTCTCGATGA
ACCACTACAGGGGCTTGATCCGCTCAATCGCCAGCTTATCCGCCGTTTTGTTGATGTGCTGATTAGCGAAGGTGAAACGC
AATTGTTGTTTGTTTCGCACCACGCTGAAGATGCGCCTGCCTGTATTACCCATCGCCTTGAGTTCGTGCCGGACGGTGGA
CTCTATCGCTATGTGCTGACAAAAATATATTGA

Upstream 100 bases:

>100_bases
GCCGACAGCGTGATTATCGCCACGCTGTGCTAAGCGTGTTGACAATTTGTTATGAAACACGTATCCCTGTCAGTAATCGC
TGCACAAAATGGGATATAAA

Downstream 100 bases:

>100_bases
GTCGGTAGTGCTGACCTTGCCGGAGGCGGCCTAAGCGCCCTCTCCGGCCAACGGTTCGACGCATGCAGGCATTAAACCGC
GTCTTTTTTTCAGATAAAAA

Product: putative molybdenum transport ATP-binding protein ModF

Products: NA

Alternate protein names: Photorepair protein PhrA [H]

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MSSLQILQGTFRLSDTKTLQLPQLTLNAGDSWAFVGSNGSGKSALARALAGELPLLKGERQSQFSHITRLSFEQLQKLVS
DEWQRNNTDMLGPGEDDTGRTTAEIIQDEVKDAPRCMQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILD
EPFDGLDVASRQQLAERLASLHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQALVAQLAHSEQLEGV
QLPEPDEPSARHALPANEPRIVLNNGVVSYNDRPILNNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTL
FGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRTADAPFH
SLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQLLFVSHHAEDAPACITHRLEFVPDGG
LYRYVLTKIY

Sequences:

>Translated_490_residues
MSSLQILQGTFRLSDTKTLQLPQLTLNAGDSWAFVGSNGSGKSALARALAGELPLLKGERQSQFSHITRLSFEQLQKLVS
DEWQRNNTDMLGPGEDDTGRTTAEIIQDEVKDAPRCMQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILD
EPFDGLDVASRQQLAERLASLHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQALVAQLAHSEQLEGV
QLPEPDEPSARHALPANEPRIVLNNGVVSYNDRPILNNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTL
FGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRTADAPFH
SLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQLLFVSHHAEDAPACITHRLEFVPDGG
LYRYVLTKIY
>Mature_489_residues
SSLQILQGTFRLSDTKTLQLPQLTLNAGDSWAFVGSNGSGKSALARALAGELPLLKGERQSQFSHITRLSFEQLQKLVSD
EWQRNNTDMLGPGEDDTGRTTAEIIQDEVKDAPRCMQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDE
PFDGLDVASRQQLAERLASLHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQALVAQLAHSEQLEGVQ
LPEPDEPSARHALPANEPRIVLNNGVVSYNDRPILNNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTLF
GRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRTADAPFHS
LSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQLLFVSHHAEDAPACITHRLEFVPDGGL
YRYVLTKIY

Specific function: Involved in the transport of molybdenum into the cell. Involved in photorepair. Could act on UV-induced DNA damage other than pyrimidine dimers [H]

COG id: COG1119

COG function: function code P; ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI27262624, Length=167, Percent_Identity=28.1437125748503, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI27262626, Length=167, Percent_Identity=28.1437125748503, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1786975, Length=490, Percent_Identity=99.7959183673469, Blast_Score=998, Evalue=0.0,
Organism=Escherichia coli, GI48994943, Length=379, Percent_Identity=27.7044854881267, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788897, Length=502, Percent_Identity=23.3067729083665, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1787041, Length=526, Percent_Identity=23.1939163498099, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1789991, Length=475, Percent_Identity=24.8421052631579, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI48995001, Length=463, Percent_Identity=23.5421166306695, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790525, Length=474, Percent_Identity=21.9409282700422, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790190, Length=480, Percent_Identity=23.5416666666667, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787792, Length=489, Percent_Identity=24.1308793456033, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI2367384, Length=483, Percent_Identity=24.4306418219462, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787029, Length=206, Percent_Identity=30.0970873786408, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI145693107, Length=496, Percent_Identity=23.3870967741935, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789593, Length=223, Percent_Identity=28.2511210762332, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786319, Length=193, Percent_Identity=31.0880829015544, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788225, Length=180, Percent_Identity=28.3333333333333, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081782, Length=203, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1786563, Length=197, Percent_Identity=30.4568527918782, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790544, Length=184, Percent_Identity=30.4347826086957, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786253, Length=201, Percent_Identity=27.8606965174129, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788472, Length=480, Percent_Identity=22.0833333333333, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082268, Length=198, Percent_Identity=28.2828282828283, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788761, Length=219, Percent_Identity=26.9406392694064, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1787112, Length=230, Percent_Identity=27.3913043478261, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=236, Percent_Identity=29.2372881355932, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115533608, Length=229, Percent_Identity=27.9475982532751, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320266, Length=393, Percent_Identity=29.5165394402036, Blast_Score=161, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24650853, Length=237, Percent_Identity=32.0675105485232, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24650855, Length=237, Percent_Identity=32.0675105485232, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281362751, Length=237, Percent_Identity=32.0675105485232, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI28574744, Length=196, Percent_Identity=28.0612244897959, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221512771, Length=202, Percent_Identity=26.2376237623762, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920532, Length=183, Percent_Identity=29.5081967213115, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24580930, Length=183, Percent_Identity=29.5081967213115, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI85725262, Length=214, Percent_Identity=29.9065420560748, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 54551; Mature: 54419

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLQILQGTFRLSDTKTLQLPQLTLNAGDSWAFVGSNGSGKSALARALAGELPLLKGER
CCCCHHHHHHEEECCCCEEECCEEEECCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCH
QSQFSHITRLSFEQLQKLVSDEWQRNNTDMLGPGEDDTGRTTAEIIQDEVKDAPRCMQLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHH
QQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAERLAS
HHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQALVAQLAHSEQLEGV
HHHCCCEEEEEHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
QLPEPDEPSARHALPANEPRIVLNNGVVSYNDRPILNNLSWQVNPGEHWQIVGPNGAGKS
CCCCCCCCCCCCCCCCCCCEEEEECCEEEECCCCCCCCCCEEECCCCCEEEECCCCCCHH
TLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVIL
HHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHH
SGYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRTADAPFHSLSWGQQRLALIVRALVKHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
TLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQLLFVSHHAEDAPACITHRLEFVPDGG
EEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCC
LYRYVLTKIY
HHHHHHHHCC
>Mature Secondary Structure 
SSLQILQGTFRLSDTKTLQLPQLTLNAGDSWAFVGSNGSGKSALARALAGELPLLKGER
CCCHHHHHHEEECCCCEEECCEEEECCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCH
QSQFSHITRLSFEQLQKLVSDEWQRNNTDMLGPGEDDTGRTTAEIIQDEVKDAPRCMQLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHH
QQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAERLAS
HHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQALVAQLAHSEQLEGV
HHHCCCEEEEEHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
QLPEPDEPSARHALPANEPRIVLNNGVVSYNDRPILNNLSWQVNPGEHWQIVGPNGAGKS
CCCCCCCCCCCCCCCCCCCEEEEECCEEEECCCCCCCCCCEEECCCCCEEEECCCCCCHH
TLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVIL
HHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHH
SGYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRTADAPFHSLSWGQQRLALIVRALVKHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
TLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQLLFVSHHAEDAPACITHRLEFVPDGG
EEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCC
LYRYVLTKIY
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8564363; 8550508; 8905232; 9278503; 8310005 [H]