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The map label for this gene is kdpE [H]

Identifier: 157160174

GI number: 157160174

Start: 747136

End: 747813

Strand: Reverse

Name: kdpE [H]

Synonym: EcHS_A0741

Alternate gene names: 157160174

Gene position: 747813-747136 (Counterclockwise)

Preceding gene: 157160175

Following gene: 157160169

Centisome position: 16.1

GC content: 56.49

Gene sequence:

>678_bases
GTGACAAACGTTCTGATTGTTGAAGATGAACAGGCTATTCGTCGCTTTCTGCGCACGGCGCTGGAGGGCGACGGGATGCG
CGTCTATGAGGCCGAAACGCTGCAACGCGGCTTGCTGGAAGCGGCTACCCGTAAGCCAGATTTGATTATTCTCGATCTCG
GCCTGCCCGATGGTGATGGGATTGAGTTTATCCGCGACCTGCGCCAGTGGAGTGCGGTGCCGGTGATTGTGCTTTCCGCA
CGCAGCGAAGAGAGCGACAAAATCGCCGCGCTGGATGCCGGAGCGGATGATTATCTGAGTAAGCCGTTTGGCATTGGCGA
ATTGCAGGCCCGTCTGCGCGTCGCATTACGCCGCCACTCTGCCACCACCGCACCCGATCCGCTGGTGAAATTTTCCGATG
TTACCGTCGATTTAGCCGCCCGCGTGATTCACCGGGGTGAGGAAGAGGTGCATCTCACACCAATTGAGTTCCGCCTGCTG
GCGGTGCTGCTCAACAATGCCGGAAAAGTACTCACCCAGCGCCAGCTCCTTAACCAGGTGTGGGGGCCAAACGCGGTCGA
ACACAGTCACTATTTGCGTATTTATATGGGACATCTGCGACAAAAACTGGAACAGGATCCCGCCCGCCCACGCCATTTCA
TTACTGAAACCGGTATTGGGTATCGGTTTATGCTTTGA

Upstream 100 bases:

>100_bases
GCACTATTACCGCGTTCAACCGACCGGAAGGTGGTGCCTGTTTTCGTGTTACACTTCCCCAGCAAACTGCCCCTGAACTT
GAAGAATTTCATGAGGATAT

Downstream 100 bases:

>100_bases
ATTGTTATTCAATAAATTCGCTTAAATAGTGATTAATTTATTATTAAACCTGCACCAAATATTATTATTTGGCAGGTTTA
ATTTCTTAACGCAAATATAA

Product: DNA-binding transcriptional activator KdpE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MTNVLIVEDEQAIRRFLRTALEGDGMRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDGIEFIRDLRQWSAVPVIVLSA
RSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHSATTAPDPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLL
AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETGIGYRFML

Sequences:

>Translated_225_residues
MTNVLIVEDEQAIRRFLRTALEGDGMRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDGIEFIRDLRQWSAVPVIVLSA
RSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHSATTAPDPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLL
AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETGIGYRFML
>Mature_224_residues
TNVLIVEDEQAIRRFLRTALEGDGMRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDGIEFIRDLRQWSAVPVIVLSAR
SEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHSATTAPDPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLLA
VLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETGIGYRFML

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=99.5555555555556, Blast_Score=452, Evalue=1e-129,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=36.7713004484305, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=35.2678571428571, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=36.322869955157, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=33.3333333333333, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=35.5855855855856, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1786784, Length=220, Percent_Identity=35.4545454545455, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=31.981981981982, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=32.7354260089686, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=33.6363636363636, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=31.4410480349345, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=29.9559471365639, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=31.140350877193, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=27.9661016949153, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1788550, Length=121, Percent_Identity=33.8842975206612, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790299, Length=136, Percent_Identity=30.8823529411765, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790437, Length=131, Percent_Identity=30.5343511450382, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25379; Mature: 25247

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNVLIVEDEQAIRRFLRTALEGDGMRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDG
CCCEEEECCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCH
IEFIRDLRQWSAVPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHS
HHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHCC
ATTAPDPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLLAVLLNNAGKVLTQRQLLNQV
CCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHCCHHHHHHHHHHHHH
WGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETGIGYRFML
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEECC
>Mature Secondary Structure 
TNVLIVEDEQAIRRFLRTALEGDGMRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDG
CCEEEECCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCH
IEFIRDLRQWSAVPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHS
HHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHCC
ATTAPDPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLLAVLLNNAGKVLTQRQLLNQV
CCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHCCHHHHHHHHHHHHH
WGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETGIGYRFML
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]