Click here to switch to the map view.

The map label for this gene is citG [H]

Identifier: 157160109

GI number: 157160109

Start: 682711

End: 683589

Strand: Reverse

Name: citG [H]

Synonym: EcHS_A0664

Alternate gene names: 157160109

Gene position: 683589-682711 (Counterclockwise)

Preceding gene: 157160110

Following gene: 157160108

Centisome position: 14.72

GC content: 54.95

Gene sequence:

>879_bases
ATGTCGATGCCTGCAACGTCAACTAAAACCACAAAGCTTGCGACGTCATTAATCGATGAGTACGCCCTGCTGGGCTGGCG
CGCCATGCTGACTGAAGTCAATCTGTCACCGAAACCAGGCCTCGTGGATCGCATTAACTGCGGTGCGCACAAAGATATGG
CGCTGGAAGATTTCCACCGCAGCGCGCTGGCGATTCAGGGCTGGCTACCCCGTTTCATTGAATTTGGTGCCTGTAGTGCG
GAAATGGCACCAGAAGCGGTACTCCACGGATTACGCCCAATTGGTATGGCTTGCGAAGGTGATATGTTCCGCGCCACTGC
GGGCGTAAACACGCATAAAGGCAGCATTTTTTCTTTAGGGCTGCTATGTGCGGCAATTGGCCGTTTGCTTCAACTCAACC
AACCGGTAACGCCAACAACCGTTTGTTCTACGGCGGCAAGTTTCTGCCGTGGCCTGACCGATCGCGAACTGCGTACCAAT
AATTCACAACTGACGGCAGGTCAACGGTTGTACCAACAGCTTGGCCTTACCGGCGCACGCGGTGAAGCCGAAGCGGGTTA
TCCACTGGTGATCAATCACGCCTTGCCGCATTACCTCACTCTGCTGGATCAGGGGTTAGATCCTGAACTGGCATTGCTCG
ATACCTTGCTCCTACTGATGGCGATCAACGGCGATACCAACGTTGCATCGCGCGGTGGCGAGGGGGGCCTGCGCTGGCTA
CAGCGCGAGGCGCAAACATTATTGCAAAAAGGGGGCATTCGAACCCCCGCCGATCTCGATTATCTCCGGCAGTTCGACAG
GGAGTGTATCGAACGAAATCTCAGTCCAGGCGGCAGTGCCGACCTGCTGATCCTTACCTGGTTTTTAGCACAGATTTAA

Upstream 100 bases:

>100_bases
CGCCGCTGCCTGTTGTGCGAGCAAAGCGCAGCCGTCTGCGCGCGTGGAAAAACCCATCAACTGACCGATTTACTCAACCG
CATGGAGGCACTGCTGAACG

Downstream 100 bases:

>100_bases
TTATTTAAGCACTTGATAAATTTGGAAATATTAATTTTCGGAGAACCCGTATGTCTTTAGCAAAAGATAATATATGGAAA
CTATTGGCCCCACTGGTGGT

Product: triphosphoribosyl-dephospho-CoA synthase

Products: NA

Alternate protein names: 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDRINCGAHKDMALEDFHRSALAIQGWLPRFIEFGACSA
EMAPEAVLHGLRPIGMACEGDMFRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTN
NSQLTAGQRLYQQLGLTGARGEAEAGYPLVINHALPHYLTLLDQGLDPELALLDTLLLLMAINGDTNVASRGGEGGLRWL
QREAQTLLQKGGIRTPADLDYLRQFDRECIERNLSPGGSADLLILTWFLAQI

Sequences:

>Translated_292_residues
MSMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDRINCGAHKDMALEDFHRSALAIQGWLPRFIEFGACSA
EMAPEAVLHGLRPIGMACEGDMFRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTN
NSQLTAGQRLYQQLGLTGARGEAEAGYPLVINHALPHYLTLLDQGLDPELALLDTLLLLMAINGDTNVASRGGEGGLRWL
QREAQTLLQKGGIRTPADLDYLRQFDRECIERNLSPGGSADLLILTWFLAQI
>Mature_291_residues
SMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDRINCGAHKDMALEDFHRSALAIQGWLPRFIEFGACSAE
MAPEAVLHGLRPIGMACEGDMFRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTNN
SQLTAGQRLYQQLGLTGARGEAEAGYPLVINHALPHYLTLLDQGLDPELALLDTLLLLMAINGDTNVASRGGEGGLRWLQ
REAQTLLQKGGIRTPADLDYLRQFDRECIERNLSPGGSADLLILTWFLAQI

Specific function: Catalyzes the formation of 2-(5''-triphosphoribosyl)-3'- dephosphocoenzyme-A, the precursor of the prosthetic group of the holo-acyl carrier protein (gamma chain) of citrate lyase, from ATP and dephospho-CoA [H]

COG id: COG1767

COG function: function code H; Triphosphoribosyl-dephospho-CoA synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitG/MdcB family [H]

Homologues:

Organism=Escherichia coli, GI1786830, Length=292, Percent_Identity=100, Blast_Score=594, Evalue=1e-171,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002736
- InterPro:   IPR017551 [H]

Pfam domain/function: PF01874 CitG [H]

EC number: =2.7.8.25 [H]

Molecular weight: Translated: 31645; Mature: 31514

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDRINCGAHKDMALEDFHR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
SALAIQGWLPRFIEFGACSAEMAPEAVLHGLRPIGMACEGDMFRATAGVNTHKGSIFSLG
HHHHHHHHHHHHHHHCCCCHHCCHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHH
LLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTNNSQLTAGQRLYQQLGLTGAR
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCC
GEAEAGYPLVINHALPHYLTLLDQGLDPELALLDTLLLLMAINGDTNVASRGGEGGLRWL
CCCCCCCCEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCCHHHHHH
QREAQTLLQKGGIRTPADLDYLRQFDRECIERNLSPGGSADLLILTWFLAQI
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHC
>Mature Secondary Structure 
SMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDRINCGAHKDMALEDFHR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
SALAIQGWLPRFIEFGACSAEMAPEAVLHGLRPIGMACEGDMFRATAGVNTHKGSIFSLG
HHHHHHHHHHHHHHHCCCCHHCCHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHH
LLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTNNSQLTAGQRLYQQLGLTGAR
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHCCCCCC
GEAEAGYPLVINHALPHYLTLLDQGLDPELALLDTLLLLMAINGDTNVASRGGEGGLRWL
CCCCCCCCEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCCHHHHHH
QREAQTLLQKGGIRTPADLDYLRQFDRECIERNLSPGGSADLLILTWFLAQI
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA