Click here to switch to the map view.

The map label for this gene is ybdH

Identifier: 157160096

GI number: 157160096

Start: 668470

End: 669558

Strand: Reverse

Name: ybdH

Synonym: EcHS_A0651

Alternate gene names: 157160096

Gene position: 669558-668470 (Counterclockwise)

Preceding gene: 157160098

Following gene: 157160088

Centisome position: 14.42

GC content: 55.19

Gene sequence:

>1089_bases
ATGCCTCACAATCCTATCCGCGTGGTCGTCGGCCCGGCTAACTACTTTTCACATCCAGGAAGTTTCAATCACCTGCACGA
TTTTTTCACTGATGAACAACTTTCTCGCGCGGTGTGGATCTACGGCAAACGCGCCATTGCTGCGGCGCAAACCAAACTTC
CGCCAGCGTTTGGACTGCCAGGGGCAAAGCATATTTTGTTTCGCGGTCATTGCAGCGAAAGCGATGTACAACAACTGGCG
GCTGAGTCCGGTGACGACCGCAGCGTGGTGATTGGCGTCGGTGGCGGTGCACTGCTCGACACCGCGAAAGCCCTCGCCCG
CCGTCTCGGTCTGCCGTTTGTTGCCGTTCCGACGATCGCCGCCACCTGCGCCGCCTGGACACCGCTCTCCGTCTGGTATA
ATGATGCCGGACAGGCGCTGCATTATGAGATTTTCGACGACGCCAATTTTATGGTGCTGGTGGAACCGGAGATTATCCTC
AATGCACCGCAACAATATCTGCTGGCGGGGATCGGTGACACGCTGGCGAAATGGTATGAAGCGGTGGTGCTGGCTCCGCA
ACCAGAAACGTTGCCGCTAACCGTGCGACTGGGGATCAATAATGCGCAAGCCATTCGCGACGTCTTGTTAAACAGTAGCG
AACAGGCGCTGAGCGATCAGCAAAATCAACAGTTAACGCAATCATTTTGCGATGTGGTGGATGCTATTATTGCTGGTGGT
GGGATGGTTGGTGGTCTGGGCGATCGTTTTACGCGTGTGGCGGCAGCTCATGCCGTGCATAACGGTCTGACCGTGCTGCC
GCAAACCGAGAAGTTTCTCCACGGCACCAAAGTCGCCTACGGAATTCTGGTGCAAAGCGCCTTGCTGGGTCAGGATGATG
TGCTGGCGCAATTAACTGGAGCGTATCAGCGTTTTCATCTGCCGACTACACTGGCGGAGCTGGAAGTGGATATCAATAAT
CAGGCGGAGATCGACAAAGTGATTGCCCACACCCTGCGTCCGGTGGAGTCCATTCATTACCTGCCAGTCACGCTGACACC
AGATACGTTGCGTGCAGCGTTCAAAAAAGTGGAATCGTTTAAAGCCTGA

Upstream 100 bases:

>100_bases
TACCTGACGAAGTTGCGTGTTGAAGGCACTATAACACGATGCTAGTATTTGGCAATCAAGACGTTTAGATGTCTAAATAA
AACAATAAGGACAACACAAC

Downstream 100 bases:

>100_bases
CGTACAAATTTAGCAGCAGCGCGCGCCGCCTTTTCCACCGTAGCGCGCGTCCTGCCGCTCACGGAAAAACTCTTCGTAGG
TCATCGGCGTTTGATCGGGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MPHNPIRVVVGPANYFSHPGSFNHLHDFFTDEQLSRAVWIYGKRAIAAAQTKLPPAFGLPGAKHILFRGHCSESDVQQLA
AESGDDRSVVIGVGGGALLDTAKALARRLGLPFVAVPTIAATCAAWTPLSVWYNDAGQALHYEIFDDANFMVLVEPEIIL
NAPQQYLLAGIGDTLAKWYEAVVLAPQPETLPLTVRLGINNAQAIRDVLLNSSEQALSDQQNQQLTQSFCDVVDAIIAGG
GMVGGLGDRFTRVAAAHAVHNGLTVLPQTEKFLHGTKVAYGILVQSALLGQDDVLAQLTGAYQRFHLPTTLAELEVDINN
QAEIDKVIAHTLRPVESIHYLPVTLTPDTLRAAFKKVESFKA

Sequences:

>Translated_362_residues
MPHNPIRVVVGPANYFSHPGSFNHLHDFFTDEQLSRAVWIYGKRAIAAAQTKLPPAFGLPGAKHILFRGHCSESDVQQLA
AESGDDRSVVIGVGGGALLDTAKALARRLGLPFVAVPTIAATCAAWTPLSVWYNDAGQALHYEIFDDANFMVLVEPEIIL
NAPQQYLLAGIGDTLAKWYEAVVLAPQPETLPLTVRLGINNAQAIRDVLLNSSEQALSDQQNQQLTQSFCDVVDAIIAGG
GMVGGLGDRFTRVAAAHAVHNGLTVLPQTEKFLHGTKVAYGILVQSALLGQDDVLAQLTGAYQRFHLPTTLAELEVDINN
QAEIDKVIAHTLRPVESIHYLPVTLTPDTLRAAFKKVESFKA
>Mature_361_residues
PHNPIRVVVGPANYFSHPGSFNHLHDFFTDEQLSRAVWIYGKRAIAAAQTKLPPAFGLPGAKHILFRGHCSESDVQQLAA
ESGDDRSVVIGVGGGALLDTAKALARRLGLPFVAVPTIAATCAAWTPLSVWYNDAGQALHYEIFDDANFMVLVEPEIILN
APQQYLLAGIGDTLAKWYEAVVLAPQPETLPLTVRLGINNAQAIRDVLLNSSEQALSDQQNQQLTQSFCDVVDAIIAGGG
MVGGLGDRFTRVAAAHAVHNGLTVLPQTEKFLHGTKVAYGILVQSALLGQDDVLAQLTGAYQRFHLPTTLAELEVDINNQ
AEIDKVIAHTLRPVESIHYLPVTLTPDTLRAAFKKVESFKA

Specific function: Unknown

COG id: COG0371

COG function: function code C; Glycerol dehydrogenase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1786815, Length=362, Percent_Identity=100, Blast_Score=741, Evalue=0.0,
Organism=Escherichia coli, GI87082352, Length=359, Percent_Identity=31.7548746518106, Blast_Score=151, Evalue=7e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YBDH_ECOLI (P45579)

Other databases:

- EMBL:   U82598
- EMBL:   U00096
- EMBL:   AP009048
- EMBL:   X52904
- PIR:   E64793
- RefSeq:   AP_001247.1
- RefSeq:   NP_415132.1
- ProteinModelPortal:   P45579
- DIP:   DIP-11347N
- MINT:   MINT-1302765
- PRIDE:   P45579
- EnsemblBacteria:   EBESCT00000001630
- EnsemblBacteria:   EBESCT00000015873
- GeneID:   945212
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW0592
- KEGG:   eco:b0599
- EchoBASE:   EB2555
- EcoGene:   EG12692
- eggNOG:   COG0371
- GeneTree:   EBGT00050000009410
- HOGENOM:   HBG399530
- OMA:   GGAQCRT
- ProtClustDB:   PRK10586
- BioCyc:   EcoCyc:EG12692-MONOMER
- Genevestigator:   P45579
- InterPro:   IPR001670
- InterPro:   IPR018211
- InterPro:   IPR016205
- PIRSF:   PIRSF000112

Pfam domain/function: PF00465 Fe-ADH

EC number: 1.1.-.- [C]

Molecular weight: Translated: 39092; Mature: 38961

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS00913 ADH_IRON_1; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHNPIRVVVGPANYFSHPGSFNHLHDFFTDEQLSRAVWIYGKRAIAAAQTKLPPAFGLP
CCCCCEEEEECCHHHCCCCCCCCHHHHHHCHHHHHHEEEEECCHHHHHHHHCCCCCCCCC
GAKHILFRGHCSESDVQQLAAESGDDRSVVIGVGGGALLDTAKALARRLGLPFVAVPTIA
CCCEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEHHHHH
ATCAAWTPLSVWYNDAGQALHYEIFDDANFMVLVEPEIILNAPQQYLLAGIGDTLAKWYE
HHHHCCCCCEEEECCCCCEEEEEEECCCCEEEEECCHHEECCCHHHHHHHHHHHHHHHHH
AVVLAPQPETLPLTVRLGINNAQAIRDVLLNSSEQALSDQQNQQLTQSFCDVVDAIIAGG
EEEECCCCCCEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GMVGGLGDRFTRVAAAHAVHNGLTVLPQTEKFLHGTKVAYGILVQSALLGQDDVLAQLTG
CCCCCCHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AYQRFHLPTTLAELEVDINNQAEIDKVIAHTLRPVESIHYLPVTLTPDTLRAAFKKVESF
HHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCEEEEEEECHHHHHHHHHHHHHC
KA
CC
>Mature Secondary Structure 
PHNPIRVVVGPANYFSHPGSFNHLHDFFTDEQLSRAVWIYGKRAIAAAQTKLPPAFGLP
CCCCEEEEECCHHHCCCCCCCCHHHHHHCHHHHHHEEEEECCHHHHHHHHCCCCCCCCC
GAKHILFRGHCSESDVQQLAAESGDDRSVVIGVGGGALLDTAKALARRLGLPFVAVPTIA
CCCEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEHHHHH
ATCAAWTPLSVWYNDAGQALHYEIFDDANFMVLVEPEIILNAPQQYLLAGIGDTLAKWYE
HHHHCCCCCEEEECCCCCEEEEEEECCCCEEEEECCHHEECCCHHHHHHHHHHHHHHHHH
AVVLAPQPETLPLTVRLGINNAQAIRDVLLNSSEQALSDQQNQQLTQSFCDVVDAIIAGG
EEEECCCCCCEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GMVGGLGDRFTRVAAAHAVHNGLTVLPQTEKFLHGTKVAYGILVQSALLGQDDVLAQLTG
CCCCCCHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AYQRFHLPTTLAELEVDINNQAEIDKVIAHTLRPVESIHYLPVTLTPDTLRAAFKKVESF
HHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCEEEEEEECHHHHHHHHHHHHHC
KA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 1848300; 7567469