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The map label for this gene is sfmA

Identifier: 157160053

GI number: 157160053

Start: 617743

End: 618285

Strand: Direct

Name: sfmA

Synonym: EcHS_A0604

Alternate gene names: 157160053

Gene position: 617743-618285 (Clockwise)

Preceding gene: 157160050

Following gene: 157160054

Centisome position: 13.3

GC content: 44.75

Gene sequence:

>543_bases
ATGAAATTAAGATTTATTTCGTCTGCGCTGGCTGCCGCACTATTCGCCGCTACGGGTAGTTATGCTGCCGTTGTAGATGG
CGGTACAATTCACTTTGAAGGCGAACTGGTGAATGCTGCCTGTTCAGTGAATACTGACTCGGCAGACCAGGTTGTCACAC
TCGGTCAATATCGTACCGATATTTTCAATGCTGTTGGTAATACCTCTGCATTAATTCCATTCACCATTCAGTTGAACGAC
TGCGATCCTGTTGTTGCCGCTAATGCTGCCGTTGCATTTTCTGGTCAGGCTGATGCAATCAATGATAATTTATTGGCCAT
TGCATCCAGTACCAATACAACAACAGCAACGGGTGTCGGTATTGAAATACTTGATAATACATCCGCAATTCTCAAACCTG
ATGGGAATAGCTTCTCAACCAACCAGAACTTGATCCCCGGGACCAACGTTCTTCATTTTTCTGCACGTTATAAAGGCACC
GGTACAAGTGCATCAGCAGGGCAAGCAAATGCTGACGCGACTTTTATTATGAGATACGAATAA

Upstream 100 bases:

>100_bases
CTTAGAGGATAAAAAGGAATTTTACTACTATCAGTGTCTTAAATAAAGTAATCGGTTATATACGGATGTGGAGTCGATAA
ATGAGATTGAAGGAATATAT

Downstream 100 bases:

>100_bases
TCAAAACCACGTTGTTTTGAATTATATATCACGTCTTATAACAAAGTAATGTACCGGTTGTCTGAAGCGGTATGGTGGCA
ATGTAAATCGAAATCATGTT

Product: type-1 fimbrial protein

Products: NA

Alternate protein names: Type-1A pilin

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MKLRFISSALAAALFAATGSYAAVVDGGTIHFEGELVNAACSVNTDSADQVVTLGQYRTDIFNAVGNTSALIPFTIQLND
CDPVVAANAAVAFSGQADAINDNLLAIASSTNTTTATGVGIEILDNTSAILKPDGNSFSTNQNLIPGTNVLHFSARYKGT
GTSASAGQANADATFIMRYE

Sequences:

>Translated_180_residues
MKLRFISSALAAALFAATGSYAAVVDGGTIHFEGELVNAACSVNTDSADQVVTLGQYRTDIFNAVGNTSALIPFTIQLND
CDPVVAANAAVAFSGQADAINDNLLAIASSTNTTTATGVGIEILDNTSAILKPDGNSFSTNQNLIPGTNVLHFSARYKGT
GTSASAGQANADATFIMRYE
>Mature_180_residues
MKLRFISSALAAALFAATGSYAAVVDGGTIHFEGELVNAACSVNTDSADQVVTLGQYRTDIFNAVGNTSALIPFTIQLND
CDPVVAANAAVAFSGQADAINDNLLAIASSTNTTTATGVGIEILDNTSAILKPDGNSFSTNQNLIPGTNVLHFSARYKGT
GTSASAGQANADATFIMRYE

Specific function: Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs

COG id: COG3539

COG function: function code NU; P pilus assembly protein, pilin FimA

Gene ontology:

Cell location: Fimbrium

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial protein family

Homologues:

Organism=Escherichia coli, GI87081753, Length=180, Percent_Identity=100, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1790769, Length=157, Percent_Identity=52.2292993630573, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI87082421, Length=182, Percent_Identity=31.3186813186813, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1787781, Length=166, Percent_Identity=33.7349397590361, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1790773, Length=173, Percent_Identity=34.6820809248555, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1786746, Length=176, Percent_Identity=29.5454545454545, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1787174, Length=156, Percent_Identity=30.7692307692308, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SFMA_ECO57 (P0ABW6)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- RefSeq:   NP_286279.1
- RefSeq:   NP_308619.2
- ProteinModelPortal:   P0ABW6
- SMR:   P0ABW6
- EnsemblBacteria:   EBESCT00000024731
- EnsemblBacteria:   EBESCT00000057297
- GeneID:   916947
- GeneID:   957538
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z0686
- KEGG:   ecs:ECs0592
- GeneTree:   EBGT00050000008609
- HOGENOM:   HBG701898
- OMA:   QADNTNP
- ProtClustDB:   PRK15194
- BioCyc:   ECOL83334:ECS0592-MONOMER
- GO:   GO:0009289
- InterPro:   IPR008966
- InterPro:   IPR000259
- InterPro:   IPR014779
- Gene3D:   G3DSA:2.60.40.1090

Pfam domain/function: PF00419 Fimbrial; SSF49401 Adhes_bact

EC number: NA

Molecular weight: Translated: 18475; Mature: 18475

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRFISSALAAALFAATGSYAAVVDGGTIHFEGELVNAACSVNTDSADQVVTLGQYRTD
CEEEHHHHHHHHHHHHCCCCEEEEEECCEEEEECEEEEEEEECCCCCCCEEEEECHHHHH
IFNAVGNTSALIPFTIQLNDCDPVVAANAAVAFSGQADAINDNLLAIASSTNTTTATGVG
HHHHCCCCCEEEEEEEEECCCCCEEECCEEEEECCCCCCCCCCEEEEEECCCCCEECCCE
IEILDNTSAILKPDGNSFSTNQNLIPGTNVLHFSARYKGTGTSASAGQANADATFIMRYE
EEEECCCCEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MKLRFISSALAAALFAATGSYAAVVDGGTIHFEGELVNAACSVNTDSADQVVTLGQYRTD
CEEEHHHHHHHHHHHHCCCCEEEEEECCEEEEECEEEEEEEECCCCCCCEEEEECHHHHH
IFNAVGNTSALIPFTIQLNDCDPVVAANAAVAFSGQADAINDNLLAIASSTNTTTATGVG
HHHHCCCCCEEEEEEEEECCCCCEEECCEEEEECCCCCCCCCCEEEEEECCCCCEECCCE
IEILDNTSAILKPDGNSFSTNQNLIPGTNVLHFSARYKGTGTSASAGQANADATFIMRYE
EEEECCCCEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796