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The map label for this gene is glxK [H]

Identifier: 157160036

GI number: 157160036

Start: 601465

End: 602610

Strand: Direct

Name: glxK [H]

Synonym: EcHS_A0587

Alternate gene names: 157160036

Gene position: 601465-602610 (Clockwise)

Preceding gene: 157160035

Following gene: 157160037

Centisome position: 12.95

GC content: 55.67

Gene sequence:

>1146_bases
ATGAAGATTGTCATTGCGCCAGACTCTTTTAAAGAGAGCTTAAGTGCAGAAAAATGTTGCCAGGCAATTAAAGCCGGGTT
TTCGACCCTCTTTCCCGATGCGCACTATATCTGTTTGCCGATAGCGGATGGCGGCGAAGGAACGGTGGATGCGATGGTCG
CCGCGACGGGCGGCAACATCGTGACGCTTGAAGTCTGCGGGCCGATGGGCGAAACAGTGAATGCTTTTTATGGCCTTACC
GGCGACGGGAAAACGGCGGTGATTGAGATGGCGGCAGCAAGTGGCCTGATGCTGGTCGCGCCTGAAAAGCGTAATCCGTT
GCTGGCCTCCAGTTTTGGTACGGGGGAGTTAATTCGTCATGCGCTGGATAACGGCATTCGCCATATTATTCTCGGCATTG
GCGGCAGTGCGACGGTCGACGGCGGTATGGGCATGGCGCAGGCGCTCGGTGTGCGTTTCCTTGATGCCGACGGTCAGGTG
CTGGTGGCTAACGGCGGTAATTTAGCGCGCGTGGCAAGCATTGAGATGGATGAATGCGATCCGCGTCTGGCGAATTGCCA
TATTGAAGTAGCATGTGACGTTGATAACCCGCTGGTAGGGGCACGCGGCGCGGCGGCGGTGTTTGGCCCGCAAAAAGGGG
CAACGCCGGAAATGGTCGAAGAGCTGGAACAGGGGCTGCAAAATTACGCCCGTGTTTTACAACAGCAAACTGAAATCAAC
GTCTGCCAGATGGCGGGCGGCGGCGCTGCGGGCGGTATGGGTATTGCGGCGGCGGTATTTCTCAATGCGGATATTAAACC
AGGTATTGAGATTGTGTTGAATGCGGTCAATCTTGCGCAGGCAGTGCAGGGCGCAGCACTGGTGATTACCGGGGAAGGGC
GCATCGACTCGCAAACGGCAGGCGGTAAAGCGCCGCTGGGTGTGGCGTCGGTGGCGAAGCAGTTTAATGTACCGGTGATT
GGGATTGCTGGCGTATTGGGTGATGGCGTGGAAGTGGTGCACCAGTATGGCATTGATGCGGTATTCAGCATTTTGCCACG
TCTGGCACCTTTAGCCGAAGTACTCGCCAGCGGTGAAATCAATCTCTTCAACAGCGCGCGAAATATTGCCTGCGCCATTA
AAATAGGTCAGGGAATTAAAAACTGA

Upstream 100 bases:

>100_bases
GCTCAGTAACGGCTTATTGGTCGGGATTTTACTGGCTGTTCTTATGGATAATCTTATTCCGTGGGAACGCATCGAATAAT
TTGTTGAAAAAGGATTGATA

Downstream 100 bases:

>100_bases
CTCTTGCCTTTAAAGCGGATGCTATTTATTTCGTATAAGAGCGCAGTACTCATGCCGGATGCGGCATAAGTACTATATCC
TTCCTGAAAATCGCGCAAAT

Product: glycerate kinase II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKIVIAPDSFKESLSAEKCCQAIKAGFSTLFPDAHYICLPIADGGEGTVDAMVAATGGNIVTLEVCGPMGETVNAFYGLT
GDGKTAVIEMAAASGLMLVAPEKRNPLLASSFGTGELIRHALDNGIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQV
LVANGGNLARVASIEMDECDPRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEMVEELEQGLQNYARVLQQQTEIN
VCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLNAVNLAQAVQGAALVITGEGRIDSQTAGGKAPLGVASVAKQFNVPVI
GIAGVLGDGVEVVHQYGIDAVFSILPRLAPLAEVLASGEINLFNSARNIACAIKIGQGIKN

Sequences:

>Translated_381_residues
MKIVIAPDSFKESLSAEKCCQAIKAGFSTLFPDAHYICLPIADGGEGTVDAMVAATGGNIVTLEVCGPMGETVNAFYGLT
GDGKTAVIEMAAASGLMLVAPEKRNPLLASSFGTGELIRHALDNGIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQV
LVANGGNLARVASIEMDECDPRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEMVEELEQGLQNYARVLQQQTEIN
VCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLNAVNLAQAVQGAALVITGEGRIDSQTAGGKAPLGVASVAKQFNVPVI
GIAGVLGDGVEVVHQYGIDAVFSILPRLAPLAEVLASGEINLFNSARNIACAIKIGQGIKN
>Mature_381_residues
MKIVIAPDSFKESLSAEKCCQAIKAGFSTLFPDAHYICLPIADGGEGTVDAMVAATGGNIVTLEVCGPMGETVNAFYGLT
GDGKTAVIEMAAASGLMLVAPEKRNPLLASSFGTGELIRHALDNGIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQV
LVANGGNLARVASIEMDECDPRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEMVEELEQGLQNYARVLQQQTEIN
VCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLNAVNLAQAVQGAALVITGEGRIDSQTAGGKAPLGVASVAKQFNVPVI
GIAGVLGDGVEVVHQYGIDAVFSILPRLAPLAEVLASGEINLFNSARNIACAIKIGQGIKN

Specific function: Glyoxylate catabolism. [C]

COG id: COG1929

COG function: function code G; Glycerate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycerate kinase type-1 family [H]

Homologues:

Organism=Escherichia coli, GI1786724, Length=381, Percent_Identity=98.4251968503937, Blast_Score=744, Evalue=0.0,
Organism=Escherichia coli, GI145693185, Length=376, Percent_Identity=56.3829787234042, Blast_Score=390, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018193
- InterPro:   IPR004381 [H]

Pfam domain/function: PF02595 Gly_kinase [H]

EC number: =2.7.1.31 [H]

Molecular weight: Translated: 38741; Mature: 38741

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVIAPDSFKESLSAEKCCQAIKAGFSTLFPDAHYICLPIADGGEGTVDAMVAATGGNI
CEEEECCCHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEEECCCCE
VTLEVCGPMGETVNAFYGLTGDGKTAVIEMAAASGLMLVAPEKRNPLLASSFGTGELIRH
EEEEECCCCCCCHHHHEECCCCCCEEEEEEECCCCEEEEECCCCCCEEEECCCHHHHHHH
ALDNGIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQVLVANGGNLARVASIEMDECD
HHHCCCEEEEEECCCCCEECCCCCHHHHHCEEEECCCCEEEEECCCCEEEEEEEECCCCC
PRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEMVEELEQGLQNYARVLQQQTEIN
CCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
VCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLNAVNLAQAVQGAALVITGEGRIDSQTA
EEEECCCCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCC
GGKAPLGVASVAKQFNVPVIGIAGVLGDGVEVVHQYGIDAVFSILPRLAPLAEVLASGEI
CCCCCCCHHHHHHHCCCCEEEEHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCE
NLFNSARNIACAIKIGQGIKN
EEEECCCCEEEEEEECCCCCC
>Mature Secondary Structure
MKIVIAPDSFKESLSAEKCCQAIKAGFSTLFPDAHYICLPIADGGEGTVDAMVAATGGNI
CEEEECCCHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEEECCCCE
VTLEVCGPMGETVNAFYGLTGDGKTAVIEMAAASGLMLVAPEKRNPLLASSFGTGELIRH
EEEEECCCCCCCHHHHEECCCCCCEEEEEEECCCCEEEEECCCCCCEEEECCCHHHHHHH
ALDNGIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQVLVANGGNLARVASIEMDECD
HHHCCCEEEEEECCCCCEECCCCCHHHHHCEEEECCCCEEEEECCCCEEEEEEEECCCCC
PRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEMVEELEQGLQNYARVLQQQTEIN
CCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
VCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLNAVNLAQAVQGAALVITGEGRIDSQTA
EEEECCCCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCC
GGKAPLGVASVAKQFNVPVIGIAGVLGDGVEVVHQYGIDAVFSILPRLAPLAEVLASGEI
CCCCCCCHHHHHHHCCCCEEEEHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCE
NLFNSARNIACAIKIGQGIKN
EEEECCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10601204; 9278503 [H]