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The map label for this gene is ybaT

Identifier: 157160015

GI number: 157160015

Start: 578742

End: 580034

Strand: Direct

Name: ybaT

Synonym: EcHS_A0565

Alternate gene names: 157160015

Gene position: 578742-580034 (Clockwise)

Preceding gene: 157160014

Following gene: 157160016

Centisome position: 12.46

GC content: 53.29

Gene sequence:

>1293_bases
ATGATGAACACGGAAGGTAATAACGGTAACAAACCTCTCGGTCTATGGAACGTCGTTTCCATCGGCATTGGGGCAATGGT
GGGGGCGGGGATCTTCGCGCTGCTGGGGCAGGCTGCATTGCTAATGGAAGCCTCGACCTGGGTCGCCTTTGCTTTTGGCG
GTATTGTGGCGATGTTTTCCGGTTATGCCTATGCGCGTCTGGGGGCGAGCTATCCCAGCAATGGCGGCATTATCGACTTC
TTTCGTCGCGGATTAGGCAACGGCGTCTTTTCGCTGGCGCTCTCGTTACTGTACCTGTTGACGCTGGCGGTGAGCATCGC
CATGGTCGCCCGTGCTTTTGGCGCTTATGCCGTGCAGTTTTTGCATGAAGGCAGCCAGGAGGAGCACCTTATTTTGCTCT
ACGCGTTGGGGATCATTGCGGTGATGACGCTTTTCAACTCCTTAAGCAACCATGCGGTAGGGCGGCTGGAAGTGATCCTC
GTCGGCATTAAAATGATGATCCTGTTATTGCTGATTATTGCCGGTGTCTGGTCGCTGCAACCGGCGCATATTTCCGTCTC
TGCGCCCCCCAGCTCCGGTGCGTTCTTCTCCTGTATTGGGATAACTTTCCTTGCCTATGCGGGCTTTGGCATGATGGCGA
ACGCGGCGGATAAAGTGAAAGATCCGCAGGTCATTATGCCACGGGCGTTTCTGGTGGCGATTGGCGTTACCACGTTGCTT
TATATCTCGCTGGCACTGGTTTTGCTTAGCGATGTATCGGCATTAGAGTTAGAAAAATATGCCGATACCGCCGTAGCGCA
GGCTGCTTCTCCGCTGCTCGGGCATGTGGGTTATGTGATCGTCGTCATCGGCGCTTTACTGGCGACGGCTTCAGCCATTA
ACGCGAACCTGTTCGCCGTGTTTAACATCATGGACAACATGGGCAGCGAACGCGAACTGCCGAAGCTAATGAATAAATCC
CTGTGGCGGCAGAGTACCTGGGGCAACATTATTGTCGTGGTGTTGATTATGCTGATGACGGCGGCACTGAATTTAGGCTC
ACTCGCCAGCGTTGCCAGCGCCACCTTTTTGATTTGCTACCTGGCGGTGTTTGTGGTGGCGATCCGCCTGCGTCATGATA
TTCACGCCTCGTTGCCGATTCTTATCGTTGGTACGTTGGTGATGTTGTTGGTGATCGTTGGCTTTATCTACAGTCTGTGG
TCCCAGGGTAGCCGTGCGTTGATATGGATTATTGGCTCACTCTTACTCAGCCTTATTGTGGCAATGGTCATGAAGCGCAA
TAAAACCGTATAA

Upstream 100 bases:

>100_bases
TCTCACCACCGCTGGACGAAGAAGGCAACAGTGTTCGCGGTCAAAAAATGGTGGCATCGGTCGCTAACCAACTCGGCTAT
AACGTGTTTAAGGGCTGATC

Downstream 100 bases:

>100_bases
CATCTCTCTGTGCGCAGTACTTCCTGTATTATTGTGGTGGCGGTCGATATTCGCACTGGCAAAAAAACGTGCTTGAATAT
CTGTTGAAACCCTTTAACAA

Product: amino acid permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MMNTEGNNGNKPLGLWNVVSIGIGAMVGAGIFALLGQAALLMEASTWVAFAFGGIVAMFSGYAYARLGASYPSNGGIIDF
FRRGLGNGVFSLALSLLYLLTLAVSIAMVARAFGAYAVQFLHEGSQEEHLILLYALGIIAVMTLFNSLSNHAVGRLEVIL
VGIKMMILLLLIIAGVWSLQPAHISVSAPPSSGAFFSCIGITFLAYAGFGMMANAADKVKDPQVIMPRAFLVAIGVTTLL
YISLALVLLSDVSALELEKYADTAVAQAASPLLGHVGYVIVVIGALLATASAINANLFAVFNIMDNMGSERELPKLMNKS
LWRQSTWGNIIVVVLIMLMTAALNLGSLASVASATFLICYLAVFVVAIRLRHDIHASLPILIVGTLVMLLVIVGFIYSLW
SQGSRALIWIIGSLLLSLIVAMVMKRNKTV

Sequences:

>Translated_430_residues
MMNTEGNNGNKPLGLWNVVSIGIGAMVGAGIFALLGQAALLMEASTWVAFAFGGIVAMFSGYAYARLGASYPSNGGIIDF
FRRGLGNGVFSLALSLLYLLTLAVSIAMVARAFGAYAVQFLHEGSQEEHLILLYALGIIAVMTLFNSLSNHAVGRLEVIL
VGIKMMILLLLIIAGVWSLQPAHISVSAPPSSGAFFSCIGITFLAYAGFGMMANAADKVKDPQVIMPRAFLVAIGVTTLL
YISLALVLLSDVSALELEKYADTAVAQAASPLLGHVGYVIVVIGALLATASAINANLFAVFNIMDNMGSERELPKLMNKS
LWRQSTWGNIIVVVLIMLMTAALNLGSLASVASATFLICYLAVFVVAIRLRHDIHASLPILIVGTLVMLLVIVGFIYSLW
SQGSRALIWIIGSLLLSLIVAMVMKRNKTV
>Mature_430_residues
MMNTEGNNGNKPLGLWNVVSIGIGAMVGAGIFALLGQAALLMEASTWVAFAFGGIVAMFSGYAYARLGASYPSNGGIIDF
FRRGLGNGVFSLALSLLYLLTLAVSIAMVARAFGAYAVQFLHEGSQEEHLILLYALGIIAVMTLFNSLSNHAVGRLEVIL
VGIKMMILLLLIIAGVWSLQPAHISVSAPPSSGAFFSCIGITFLAYAGFGMMANAADKVKDPQVIMPRAFLVAIGVTTLL
YISLALVLLSDVSALELEKYADTAVAQAASPLLGHVGYVIVVIGALLATASAINANLFAVFNIMDNMGSERELPKLMNKS
LWRQSTWGNIIVVVLIMLMTAALNLGSLASVASATFLICYLAVFVVAIRLRHDIHASLPILIVGTLVMLLVIVGFIYSLW
SQGSRALIWIIGSLLLSLIVAMVMKRNKTV

Specific function: Probable amino-acid or metabolite transport protein

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily

Homologues:

Organism=Escherichia coli, GI1786694, Length=430, Percent_Identity=100, Blast_Score=842, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71995388, Length=331, Percent_Identity=24.773413897281, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71995382, Length=331, Percent_Identity=24.773413897281, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI221331183, Length=304, Percent_Identity=25.3289473684211, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17647653, Length=304, Percent_Identity=25.3289473684211, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24664379, Length=304, Percent_Identity=25.3289473684211, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550968, Length=402, Percent_Identity=22.8855721393035, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19921172, Length=402, Percent_Identity=22.8855721393035, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24667468, Length=324, Percent_Identity=26.2345679012346, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24666159, Length=402, Percent_Identity=22.3880597014925, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221512776, Length=402, Percent_Identity=22.3880597014925, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24651635, Length=315, Percent_Identity=22.2222222222222, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24651633, Length=315, Percent_Identity=22.2222222222222, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YBAT_ECOLI (P77400)

Other databases:

- EMBL:   U82664
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   E64779
- RefSeq:   AP_001135.1
- RefSeq:   NP_415019.1
- ProteinModelPortal:   P77400
- SMR:   P77400
- DIP:   DIP-11308N
- MINT:   MINT-1267628
- STRING:   P77400
- EnsemblBacteria:   EBESCT00000000932
- EnsemblBacteria:   EBESCT00000018330
- GeneID:   945363
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW0475
- KEGG:   eco:b0486
- EchoBASE:   EB3037
- EcoGene:   EG13248
- eggNOG:   COG0531
- GeneTree:   EBGT00050000009006
- HOGENOM:   HBG575406
- OMA:   SIAVMTL
- ProtClustDB:   CLSK879681
- BioCyc:   EcoCyc:B0486-MONOMER
- Genevestigator:   P77400
- InterPro:   IPR004841
- InterPro:   IPR002293
- PANTHER:   PTHR11785
- PIRSF:   PIRSF006060

Pfam domain/function: PF00324 AA_permease

EC number: NA

Molecular weight: Translated: 45659; Mature: 45659

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12fccea4)-; HASH(0x12486cd4)-; HASH(0x11d7e2f4)-; HASH(0x12e33810)-; HASH(0x132b0f5c)-; HASH(0x1278e4a0)-; HASH(0x131bc08c)-; HASH(0x12c3b7b0)-; HASH(0x132b3934)-; HASH(0x131cb79c)-; HASH(0x11ead0e8)-; HASH(0x12cfbb90)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNTEGNNGNKPLGLWNVVSIGIGAMVGAGIFALLGQAALLMEASTWVAFAFGGIVAMFS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GYAYARLGASYPSNGGIIDFFRRGLGNGVFSLALSLLYLLTLAVSIAMVARAFGAYAVQF
CHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHEGSQEEHLILLYALGIIAVMTLFNSLSNHAVGRLEVILVGIKMMILLLLIIAGVWSLQ
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PAHISVSAPPSSGAFFSCIGITFLAYAGFGMMANAADKVKDPQVIMPRAFLVAIGVTTLL
CCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHCCHHHCCCCCEEHHHHHHHHHHHHHHH
YISLALVLLSDVSALELEKYADTAVAQAASPLLGHVGYVIVVIGALLATASAINANLFAV
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
FNIMDNMGSERELPKLMNKSLWRQSTWGNIIVVVLIMLMTAALNLGSLASVASATFLICY
HHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LAVFVVAIRLRHDIHASLPILIVGTLVMLLVIVGFIYSLWSQGSRALIWIIGSLLLSLIV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AMVMKRNKTV
HHHHHCCCCH
>Mature Secondary Structure
MMNTEGNNGNKPLGLWNVVSIGIGAMVGAGIFALLGQAALLMEASTWVAFAFGGIVAMFS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GYAYARLGASYPSNGGIIDFFRRGLGNGVFSLALSLLYLLTLAVSIAMVARAFGAYAVQF
CHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHEGSQEEHLILLYALGIIAVMTLFNSLSNHAVGRLEVILVGIKMMILLLLIIAGVWSLQ
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PAHISVSAPPSSGAFFSCIGITFLAYAGFGMMANAADKVKDPQVIMPRAFLVAIGVTTLL
CCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHCCHHHCCCCCEEHHHHHHHHHHHHHHH
YISLALVLLSDVSALELEKYADTAVAQAASPLLGHVGYVIVVIGALLATASAINANLFAV
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
FNIMDNMGSERELPKLMNKSLWRQSTWGNIIVVVLIMLMTAALNLGSLASVASATFLICY
HHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LAVFVVAIRLRHDIHASLPILIVGTLVMLLVIVGFIYSLWSQGSRALIWIIGSLLLSLIV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AMVMKRNKTV
HHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503