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The map label for this gene is ylaB [H]

Identifier: 157159983

GI number: 157159983

Start: 543132

End: 544688

Strand: Reverse

Name: ylaB [H]

Synonym: EcHS_A0533

Alternate gene names: 157159983

Gene position: 544688-543132 (Counterclockwise)

Preceding gene: 157159984

Following gene: 157159981

Centisome position: 11.73

GC content: 48.04

Gene sequence:

>1557_bases
ATGCTGGTGAGAACACGACATCTGGTCGGCCTTATTTCGGGAGTACTGATTCTTTCAGTATTGCTGCCTGTCGGCTTAAG
CATCTGGCTGGCCCATCAGCAGGTAGAAACATCGTTTATTGAAGAGCTGGATACCTATTCCTCCCGCGTCGCTATTCGAG
CCAATAAGGTGGCGACACAAGGGAAAGATGCGCTGCAGGAGCTGGAAAGATGGCAAGGCGCTGCCTGTAGCGAAGCCCAT
CTCATGGAAATGCGTCGGGTATCTTACAGTTATCGCTATATTCAGGAAGTGGCTTATATCGATAACAACGTTCCCCAGTG
TTCGTCTCTGGAGCATGAAAGTCCGCCCGATACCTTCCCCGAGCCAGGTAAAATTTCGAAAGATGGTTATCGTGTCTGGT
TAACATCGCATAACGATTTAGGCATTATCCGTTACATGGTCGCCATGGGAACGGCACATTATGTCGTCATGATCGACCCC
GCTTCCTTTATTGATGTCATTCCCTATAGCTCATGGCAAATTGATGCCGCCATTATTGGCAATGCCCATAACGTTGTCAT
AACCAGCAGCGATGAAATTGCTCAGGGAATTATTACCAGGCTACAAAAAACACCCGGTGAGCATATCGAAAATAATGGAA
TCATTTACGATATCCTGCCCTTACCGGAGATGAATATTTCGATCATCACATGGGCTTCAACGAAAATGTTGCAGAAAGGC
TGGCATCGGCAAGTCTTTATTTGGTTACCGCTCGGGTTGGTGATTGGCCTGCTGGCAGCGATGTTTGTGCTGCGTATTTT
GCGCCGTATTCAGTCACCGCATCATCGGCTGCAGGATGCTATCGATAATCGTGATATTTGCGTGCACTATCAGCCGATTG
TCTCCTTAGCCAATGGCAAAATTGTCGGTGCTGAGGCACTGGCGCGCTGGCCGCAGACAGACGGTAGTTGGTTGTCACCA
GATAGTTTTATTCCGCTGGCACAGCAAACGGGCCTTTCTGAGCCATTGACGCTACTGATTATAAGAAGCGTCTTTGAAGA
TATGGGCGACTGGCTGCGTCAGCATCCACAGCAGCATATTTCGATCAATCTTGAATCCCCCGTGCTCACCTCGGAAAAAA
TCCCGCAATTGCTGCGTGACATGATCAATCACTATCAGGTTAATCCCAGACAGATCGCGCTTGAACTCACTGAACGCGAG
TTTGCCGATCCGAAAACCAGCGCCCCGATAATTTCTCGCTACCGGGAGGCGGGCCATGAAATTTATCTTGATGATTTTGG
TACGGGGTATTCAAGTTTAAGTTATTTACAGGATCTGGATGTCGACATTCTGAAGATCGATAAATCTTTCGTTGATGCGC
TGGAATATAAAAATGTCACGCCGCATATCATCGAAATGGCAAAAACACTGAAACTGAAAATGGTAGCGGAGGGAATCGAA
ACCAGTAAACAAGAAGAGTGGTTACGCCAGCATGGCGTGCACTACGGTCAGGGCTGGCTCTACAGCAAGGCATTACCGAA
AGAAGATTTCTTACGCTGGGCCGAGCAACATTTGTGA

Upstream 100 bases:

>100_bases
TCCACCCATCACTTCATGAAATACCAGCTCTACCTCCTTATCTCCAGCCAGCCTTTTTCCACAATCAGATATACTTTCCC
TACACTGTGTTAATAAGGAT

Downstream 100 bases:

>100_bases
ATTTTTGGGCTGACGGCACGCCGCACAGCCCGTCACGCTACCTATTCGTCGATGATTGACTCGAATCCGCCATAGATCAT
TCGCTTGCCGTCAAACGGCA

Product: cyclic diguanylate phosphodiesterase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MLVRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTYSSRVAIRANKVATQGKDALQELERWQGAACSEAH
LMEMRRVSYSYRYIQEVAYIDNNVPQCSSLEHESPPDTFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDP
ASFIDVIPYSSWQIDAAIIGNAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILPLPEMNISIITWASTKMLQKG
WHRQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIDNRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSP
DSFIPLAQQTGLSEPLTLLIIRSVFEDMGDWLRQHPQQHISINLESPVLTSEKIPQLLRDMINHYQVNPRQIALELTERE
FADPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIE
TSKQEEWLRQHGVHYGQGWLYSKALPKEDFLRWAEQHL

Sequences:

>Translated_518_residues
MLVRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTYSSRVAIRANKVATQGKDALQELERWQGAACSEAH
LMEMRRVSYSYRYIQEVAYIDNNVPQCSSLEHESPPDTFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDP
ASFIDVIPYSSWQIDAAIIGNAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILPLPEMNISIITWASTKMLQKG
WHRQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIDNRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSP
DSFIPLAQQTGLSEPLTLLIIRSVFEDMGDWLRQHPQQHISINLESPVLTSEKIPQLLRDMINHYQVNPRQIALELTERE
FADPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIE
TSKQEEWLRQHGVHYGQGWLYSKALPKEDFLRWAEQHL
>Mature_518_residues
MLVRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTYSSRVAIRANKVATQGKDALQELERWQGAACSEAH
LMEMRRVSYSYRYIQEVAYIDNNVPQCSSLEHESPPDTFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDP
ASFIDVIPYSSWQIDAAIIGNAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILPLPEMNISIITWASTKMLQKG
WHRQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIDNRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSP
DSFIPLAQQTGLSEPLTLLIIRSVFEDMGDWLRQHPQQHISINLESPVLTSEKIPQLLRDMINHYQVNPRQIALELTERE
FADPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIE
TSKQEEWLRQHGVHYGQGWLYSKALPKEDFLRWAEQHL

Specific function: Unknown

COG id: COG4943

COG function: function code T; Predicted signal transduction protein containing sensor and EAL domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI87081743, Length=516, Percent_Identity=99.6124031007752, Blast_Score=1057, Evalue=0.0,
Organism=Escherichia coli, GI1790496, Length=528, Percent_Identity=33.5227272727273, Blast_Score=295, Evalue=3e-81,
Organism=Escherichia coli, GI87081845, Length=295, Percent_Identity=34.5762711864407, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1788502, Length=270, Percent_Identity=31.4814814814815, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI226510982, Length=237, Percent_Identity=35.0210970464135, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1787541, Length=247, Percent_Identity=29.9595141700405, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI87081980, Length=235, Percent_Identity=35.7446808510638, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1786507, Length=245, Percent_Identity=32.6530612244898, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87081921, Length=245, Percent_Identity=33.8775510204082, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788849, Length=263, Percent_Identity=29.6577946768061, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI87082096, Length=242, Percent_Identity=31.404958677686, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787055, Length=228, Percent_Identity=27.6315789473684, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 58919; Mature: 58919

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTYSSRVAIRANKVATQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHHHHC
GKDALQELERWQGAACSEAHLMEMRRVSYSYRYIQEVAYIDNNVPQCSSLEHESPPDTFP
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
EPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPASFIDVIPYSSWQIDAAIIG
CCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCEEEEEEEC
NAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILPLPEMNISIITWASTKMLQKG
CCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEEECHHHHHHCC
WHRQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIDNRDICVHYQPIVSLANGK
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEHHHHHHCCCC
IVGAEALARWPQTDGSWLSPDSFIPLAQQTGLSEPLTLLIIRSVFEDMGDWLRQHPQQHI
EECHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHE
SINLESPVLTSEKIPQLLRDMINHYQVNPRQIALELTEREFADPKTSAPIISRYREAGHE
EEEECCCCCCHHHHHHHHHHHHHHCCCCHHHEEEEEHHHHCCCCCCCCHHHHHHHHCCCE
IYLDDFGTGYSSLSYLQDLDVDILKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIE
EEEECCCCCHHHHHHHHHCCCHHEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
TSKQEEWLRQHGVHYGQGWLYSKALPKEDFLRWAEQHL
CCHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MLVRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTYSSRVAIRANKVATQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHHHHC
GKDALQELERWQGAACSEAHLMEMRRVSYSYRYIQEVAYIDNNVPQCSSLEHESPPDTFP
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
EPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPASFIDVIPYSSWQIDAAIIG
CCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCEEEEEEEC
NAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILPLPEMNISIITWASTKMLQKG
CCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEEECHHHHHHCC
WHRQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIDNRDICVHYQPIVSLANGK
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEHHHHHHCCCC
IVGAEALARWPQTDGSWLSPDSFIPLAQQTGLSEPLTLLIIRSVFEDMGDWLRQHPQQHI
EECHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHE
SINLESPVLTSEKIPQLLRDMINHYQVNPRQIALELTEREFADPKTSAPIISRYREAGHE
EEEECCCCCCHHHHHHHHHHHHHHCCCCHHHEEEEEHHHHCCCCCCCCHHHHHHHHCCCE
IYLDDFGTGYSSLSYLQDLDVDILKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIE
EEEECCCCCHHHHHHHHHCCCHHEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
TSKQEEWLRQHGVHYGQGWLYSKALPKEDFLRWAEQHL
CCHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]