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The map label for this gene is yajO [H]

Identifier: 157159940

GI number: 157159940

Start: 500953

End: 501927

Strand: Reverse

Name: yajO [H]

Synonym: EcHS_A0490

Alternate gene names: 157159940

Gene position: 501927-500953 (Counterclockwise)

Preceding gene: 157159941

Following gene: 157159933

Centisome position: 10.81

GC content: 53.95

Gene sequence:

>975_bases
ATGCAATACAACCCCTTAGGAAAAACCGACCTTCGCGTTTCCCGACTTTGCCTCGGCTGTATGACCTTTGGCGAGCCAGA
TCGTGGTAATCACGCATGGACACTGCCGGAAGAGAGTAGCCGTCCCATCATTAAACGCGCGCTGGAAGGCGGCATAAATT
TCTTTGATACCGCCAATAGCTATTCCGATGGCAGCAGCGAAGAGATCGTTGGTCGCGCACTGCGGGATTTCGCCCGTCGT
GAAGACGTGGTCGTTGCGACGAAAGTGTTCCATCGCGTTGGTGATTTACCGGAAGGATTATCCCGTGCACAAATTTTGCG
CTCTATCGACGACAGCCTGCGCCGTCTCGGCATGGATTATGTCGATATCCTGCAAATTCATCGCTGGGATTACAACACGC
CGATCGAAGAGACGCTGGAAGCCCTGAACGACGTGGTAAAAGCCGGGAAAGCGCGTTATATCGGCGCGTCATCCATGCAC
GCTTCGCAGTTTGCTCAGGCCCTGAAGCTACAAAAACAGCACGGCTGGGCGCAGTTTATCAGTATGCAGGATCACTACAA
TCTGATTTATCGCGAAGAAGAGCGCGAGATGCTGCCTCTGTGTTATCAGGAGGGCGTGGCGGTGATTCCGTGGAGCCCGC
TGGCGCGGGGGCGACTGACGCGTCCGTGGGGAGAAACTACCGCACGACTGGTGTCTGATGAGGTGGGGAGAAATCTCTAT
AAAGAAAGCGATGAAAATGACGCGCAGATCGCAGAGCGGTTAACGGGCGTCAGTGAAGAACTCGGTGCAACACGAGCACA
AGTTGCGCTGGCCTGGTTGTTGAGTAAACCGGGCATTGCCGCACCGATTATCGGTACATCGCGGGAAGAACAGCTTGATG
AGCTGCTGAACGCGGTGGATATCACTTTGAAGCCAGAACAGATTGCCGAACTGGAAACGCCGTATAAACCGCATGCGGTC
GTAGGATTTAAATAA

Upstream 100 bases:

>100_bases
GTGAAGCCCCAGGAGCTTACATAAGTAAGTGACTGGGGTGAACGAATGCAGCCGCAGCACATGCAACTTGAAGTATGACG
AGTATGGCAGGAGTGGCAGC

Downstream 100 bases:

>100_bases
GAGTCCAGGCCTGATGAGACGTGACAAGCGTCACATCAGGCATCGGTGCACAACTACGACAGAATACCCAGCGGCCAGTG
ATGACCGATAAAGTACAGGA

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANSYSDGSSEEIVGRALRDFARR
EDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
ASQFAQALKLQKQHGWAQFISMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGRNLY
KESDENDAQIAERLTGVSEELGATRAQVALAWLLSKPGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHAV
VGFK

Sequences:

>Translated_324_residues
MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANSYSDGSSEEIVGRALRDFARR
EDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
ASQFAQALKLQKQHGWAQFISMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGRNLY
KESDENDAQIAERLTGVSEELGATRAQVALAWLLSKPGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHAV
VGFK
>Mature_324_residues
MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANSYSDGSSEEIVGRALRDFARR
EDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
ASQFAQALKLQKQHGWAQFISMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGRNLY
KESDENDAQIAERLTGVSEELGATRAQVALAWLLSKPGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHAV
VGFK

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=320, Percent_Identity=32.8125, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI27436971, Length=333, Percent_Identity=33.3333333333333, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI27436962, Length=323, Percent_Identity=32.8173374613003, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI27436969, Length=315, Percent_Identity=32.3809523809524, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI27436966, Length=320, Percent_Identity=32.5, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI4504825, Length=313, Percent_Identity=32.2683706070287, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI223718702, Length=304, Percent_Identity=28.2894736842105, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI41152114, Length=304, Percent_Identity=27.9605263157895, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI41327764, Length=297, Percent_Identity=27.9461279461279, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI223718708, Length=139, Percent_Identity=33.8129496402878, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI87081735, Length=324, Percent_Identity=98.7654320987654, Blast_Score=663, Evalue=0.0,
Organism=Escherichia coli, GI1789375, Length=327, Percent_Identity=34.8623853211009, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1788070, Length=324, Percent_Identity=34.8765432098765, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1789199, Length=344, Percent_Identity=28.4883720930233, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788081, Length=298, Percent_Identity=28.8590604026846, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787674, Length=316, Percent_Identity=28.4810126582279, Blast_Score=98, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI212645785, Length=179, Percent_Identity=33.5195530726257, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17566692, Length=304, Percent_Identity=23.3552631578947, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=334, Percent_Identity=38.9221556886228, Blast_Score=243, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6323998, Length=338, Percent_Identity=31.6568047337278, Blast_Score=143, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6319958, Length=295, Percent_Identity=30.8474576271186, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6319951, Length=315, Percent_Identity=28.8888888888889, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6322615, Length=246, Percent_Identity=31.7073170731707, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6321052, Length=155, Percent_Identity=32.258064516129, Blast_Score=78, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24640980, Length=324, Percent_Identity=27.7777777777778, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI45549126, Length=324, Percent_Identity=27.7777777777778, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24646155, Length=318, Percent_Identity=30.8176100628931, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24646159, Length=228, Percent_Identity=32.0175438596491, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36436; Mature: 36436

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANS
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
YSDGSSEEIVGRALRDFARREDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLRRLGMDY
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHH
VDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMHASQFAQALKLQKQHGWAQFI
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHCCHHHHH
SMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGRNLY
HHHHHHHHEEECCHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KESDENDAQIAERLTGVSEELGATRAQVALAWLLSKPGIAAPIIGTSREEQLDELLNAVD
HCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHC
ITLKPEQIAELETPYKPHAVVGFK
CCCCHHHHHHCCCCCCCCEECCCC
>Mature Secondary Structure
MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANS
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
YSDGSSEEIVGRALRDFARREDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLRRLGMDY
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHH
VDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMHASQFAQALKLQKQHGWAQFI
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHCCHHHHH
SMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGRNLY
HHHHHHHHEEECCHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KESDENDAQIAERLTGVSEELGATRAQVALAWLLSKPGIAAPIIGTSREEQLDELLNAVD
HCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHC
ITLKPEQIAELETPYKPHAVVGFK
CCCCHHHHHHCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]