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The map label for this gene is tauC [H]

Identifier: 157159883

GI number: 157159883

Start: 450916

End: 451743

Strand: Direct

Name: tauC [H]

Synonym: EcHS_A0431

Alternate gene names: 157159883

Gene position: 450916-451743 (Clockwise)

Preceding gene: 157159882

Following gene: 157159884

Centisome position: 9.71

GC content: 58.21

Gene sequence:

>828_bases
ATGAGTGTGCTCATTAATGAAAAACTGCATTCGCGGCGGCTGAAATGGCGCTGGCCGCTCTCGCGTCAGGTGACCTTAAG
CATTGGCACGTTAGCGGTTTTACTCACTGTATGGTGGACGGTGGCGGCGCTGCAACTGATTAGCCCGCTGTTTTTGCCGC
CGTCGCAACAAGTACTGGCAAAACTGCTCACCATTGCCGGACCGCAGGGATTTATGGACGCCACGCTGTGGCAGCATCTG
GCAGCCAGCCTGACGCGCATTGTGCTGGCGCTACTCGCGGCGGTGGTGATCGGTATTCCGGTCGGGATCGCCATGGGGCT
AAGCCCGACGGTGCGCGGCATTCTGGATCCGGTAATCGAACTTTATCGTCCCGTGCCGCCGCTGGCTTATTTGCCGCTGA
TGGTGATCTGGTTTGGTATTGGTGAAACCTCGAAGATCTTACTGATCTATTTAGCGATTTTTGCACCGGTGGCGATGTCG
GCGCTGGCGGGGGTGAAAAGCGCGCAGCAGGTTCGCATTCGTGCCGCCCAGTCGCTGGGTGCCAGCCGTGCGCAGGTGCT
GTGGTTTGTCATTTTGCCCGGCGCGCTGCCGGAAATCCTCACCGGATTACGCATTGGTCTGGGTGTGGGCTGGTCTACGC
TGGTAGCGGCGGAGCTGATTGCCGCGACGCGCGGTTTAGGATTTATGGTTCAGTCAGCGGGTGAATTTCTCGCGACTGAC
GTGGTGCTGGCGGGAATCGCGGTGATTGCGATTATCGCCTTTCTTTTAGAACTAGGTTTGCGCGCGTTACAGCGCCGTCT
GACGCCCTGGCATGGAGAAGTACAATGA

Upstream 100 bases:

>100_bases
TTGCGGGAGAGTCGAGCCGCAGCATCAAGTCCGATCCACAATTCATCGCCATGCGCGAATATGTTTTAAGCCGCGTATTT
GAGCAACGGGAGGCGTTCTC

Downstream 100 bases:

>100_bases
GTGAACGTCTGAGCATTACCCCGCTGGGGCCGTATATCGGCGCACAAATTTCGGGTGCCGACCTGACGCGCCCGTTAAGC
GATAATCAGTTTGAACAGCT

Product: taurine transporter subunit

Products: taurine [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MSVLINEKLHSRRLKWRWPLSRQVTLSIGTLAVLLTVWWTVAALQLISPLFLPPSQQVLAKLLTIAGPQGFMDATLWQHL
AASLTRIVLALLAAVVIGIPVGIAMGLSPTVRGILDPVIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS
ALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD
VVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ

Sequences:

>Translated_275_residues
MSVLINEKLHSRRLKWRWPLSRQVTLSIGTLAVLLTVWWTVAALQLISPLFLPPSQQVLAKLLTIAGPQGFMDATLWQHL
AASLTRIVLALLAAVVIGIPVGIAMGLSPTVRGILDPVIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS
ALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD
VVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ
>Mature_274_residues
SVLINEKLHSRRLKWRWPLSRQVTLSIGTLAVLLTVWWTVAALQLISPLFLPPSQQVLAKLLTIAGPQGFMDATLWQHLA
ASLTRIVLALLAAVVIGIPVGIAMGLSPTVRGILDPVIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMSA
LAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDV
VLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ

Specific function: Part of a binding-protein-dependent transport system for taurine. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0600

COG function: function code P; ABC-type nitrate/sulfonate/bicarbonate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786564, Length=275, Percent_Identity=96.7272727272727, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI87081802, Length=238, Percent_Identity=34.0336134453782, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1789033, Length=172, Percent_Identity=31.3953488372093, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29558; Mature: 29427

Theoretical pI: Translated: 11.41; Mature: 11.41

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SVLINEKLHSRRLKWRWPLSRQVTLSIGTLAVLLTVWWTVAALQLISPLFLPPSQQVLA
CCEECCHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
KLLTIAGPQGFMDATLWQHLAASLTRIVLALLAAVVIGIPVGIAMGLSPTVRGILDPVIE
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMSALAGVKSAQQVRIRAAQSLG
HHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD
CHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
VVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: taurine [Periplasm]; ATP; H2O [C]

Specific reaction: taurine [Periplasm] + ATP + H2O = taurine [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503 [H]