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The map label for this gene is frsA [H]

Identifier: 157159721

GI number: 157159721

Start: 286173

End: 287417

Strand: Direct

Name: frsA [H]

Synonym: EcHS_A0266

Alternate gene names: 157159721

Gene position: 286173-287417 (Clockwise)

Preceding gene: 157159720

Following gene: 157159722

Centisome position: 6.16

GC content: 53.09

Gene sequence:

>1245_bases
ATGACACAGGCAAACCTGAGCGAAACCCTGTTCAAACCCCGCTTTAAACATCCTGAAACCTCGACGCTAGTCCGCCGCTT
TAATCACGGCGCACAACCGCCTGTGCAGTCGGCTCTTGATGGTAAAACCATCCCTCACTGGTATCGCATGATTAACCGTC
TGATGTGGATCTGGCGCGGTATTGACCCACGTGAAATCCTAGACGTCCAGGCACGTATTGTGATGAGCGATGCTGAACGT
ACCGACGATGATTTGTACGATACTGTGATTGGCTACCGTGGTGGCAACTGGATTTATGAGTGGGCCACCCAGGCGATGGT
GTGGCAACAAAAAGCCTGTGCGGAAGAAGATCCGCAACTCAGTGGTCGACACTGGCTGCATGCGGCTACGTTGTACAACA
TTGCCGCCTATCCTCATCTGAAAGGAGATGACCTGGCCGAGCAAGCGCAGGCTTTATCAAACCGCGCCTATGAAGAGGCC
GCCCAGCGTCTGCCGGGCACGATGCGGCAGATGGAGTTTACCGTACCCGGCGGTGCGCCCATCACCGGCTTTTTGCATAT
GCCGAAAGGCGATGGCCCGTTCCCGACAGTATTAATGTGTGGTGGTCTGGATGCGATGCAGACGGACTATTACAGCCTGT
ATGAACGTTATTTTGCGCCGCGCGGCATTGCGATGCTGACTATTGATATGCCGTCGGTGGGCTTTTCTTCAAAATGGAAG
CTCACCCAGGACTCCAGCCTGTTGCATCAGCACGTCTTAAAGGCGCTGCCTAACGTACCGTGGGTGGATCACACTCGCGT
CGCGGCCTTTGGTTTCCGTTTCGGCGCTAACGTTGCCGTGCGTCTGGCATATCTTGAATCGCCGCGTCTGAAAGCGGTTG
CCTGTCTTGGTCCGGTAGTTCATACCCTGTTGAGTGATTTTAAGTGCCAGCAACAGGTGCCGGAAATGTATCTTGACGTT
CTGGCGAGTCGTTTGGGGATGCATGATGCTTCCGACGAAGCGTTACGCGTGGAGCTGAATCGCTATTCATTAAAAGTGCA
AGGATTGCTGGGACGTCGCTGCCCAACGCCAATGTTATCAGGCTACTGGAAGAACGATCCGTTCAGCCCGGAAGAGGACT
CACGCTTAATCACCTCATCATCTGCTGACGGTAAATTATTAGAGATCCCATTTAACCCGGTGTATCGGAATTTTGACAAA
GGTCTTCAGGAAATCACCGGCTGGATCGAAAAACGCTTGTGTTAA

Upstream 100 bases:

>100_bases
GGTCGCTAATCTTTTCAACGCCTGGCACTGCCGGGCGTTGTTCTTTTTAACTTCAGGCAGGTTACAATAGTTTCCAGTAA
GTATTCTGGAGGCTGCATCC

Downstream 100 bases:

>100_bases
AAATTTGCTAAATTTTGCCAATTTGGTAAAACAGTTGCATCACAACAGGAGATAGCAATGACGTTACCGAGTGGACACCC
GAAGAGCAGATTGATCAAAA

Product: fermentation/respiration switch protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTIPHWYRMINRLMWIWRGIDPREILDVQARIVMSDAER
TDDDLYDTVIGYRGGNWIYEWATQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEA
AQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYFAPRGIAMLTIDMPSVGFSSKWK
LTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGANVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDV
LASRLGMHDASDEALRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFNPVYRNFDK
GLQEITGWIEKRLC

Sequences:

>Translated_414_residues
MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTIPHWYRMINRLMWIWRGIDPREILDVQARIVMSDAER
TDDDLYDTVIGYRGGNWIYEWATQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEA
AQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYFAPRGIAMLTIDMPSVGFSSKWK
LTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGANVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDV
LASRLGMHDASDEALRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFNPVYRNFDK
GLQEITGWIEKRLC
>Mature_413_residues
TQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTIPHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERT
DDDLYDTVIGYRGGNWIYEWATQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEAA
QRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYFAPRGIAMLTIDMPSVGFSSKWKL
TQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGANVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVL
ASRLGMHDASDEALRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFNPVYRNFDKG
LQEITGWIEKRLC

Specific function: Displays esterase activity toward pNP-butyrate [H]

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0255 family [H]

Homologues:

Organism=Escherichia coli, GI1786434, Length=414, Percent_Identity=99.5169082125604, Blast_Score=862, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010520 [H]

Pfam domain/function: PF06500 DUF1100 [H]

EC number: NA

Molecular weight: Translated: 46965; Mature: 46834

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTIPHWYRMINRLMWIWRG
CCCCCHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCC
IDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWATQAMVWQQKACAEEDPQL
CCHHHHHHHHHHHEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
SGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEAAQRLPGTMRQMEFTVPGGAP
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEECCCCCC
ITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYFAPRGIAMLTIDMPSVGFSSKWK
EEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
LTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGANVAVRLAYLESPRLKAVACLGPVV
CCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHH
HTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEALRVELNRYSLKVQGLLGRRCPTPMLS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHEEEEEHHHCCCCCCHHHC
GYWKNDPFSPEEDSRLITSSSADGKLLEIPFNPVYRNFDKGLQEITGWIEKRLC
CCCCCCCCCCCCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTIPHWYRMINRLMWIWRG
CCCCHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCC
IDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWATQAMVWQQKACAEEDPQL
CCHHHHHHHHHHHEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
SGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEAAQRLPGTMRQMEFTVPGGAP
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEECCCCCC
ITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYFAPRGIAMLTIDMPSVGFSSKWK
EEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
LTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGANVAVRLAYLESPRLKAVACLGPVV
CCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHH
HTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEALRVELNRYSLKVQGLLGRRCPTPMLS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHEEEEEHHHCCCCCCHHHC
GYWKNDPFSPEEDSRLITSSSADGKLLEIPFNPVYRNFDKGLQEITGWIEKRLC
CCCCCCCCCCCCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA