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The map label for this gene is yecS [H]

Identifier: 157157239

GI number: 157157239

Start: 2124631

End: 2125299

Strand: Reverse

Name: yecS [H]

Synonym: EcE24377A_2152

Alternate gene names: 157157239

Gene position: 2125299-2124631 (Counterclockwise)

Preceding gene: 157157688

Following gene: 157156999

Centisome position: 42.68

GC content: 53.21

Gene sequence:

>669_bases
ATGCAAGAAAGTATACAACTGGTTATTGATTCCTTGCCGTTCCTGTTGAAAGGGGCTGGGTATACCCTGCAACTCAGTAT
CGGCGGCATGTTTTTTGGCTTACTACTCGGGTTTATTCTCGCGCTGATGCGCCTGTCGCCAATCTGGCCCGTGCGCTGGA
TGGCGCGTTTTTATATCTCTATTTTTCGTGGTACGCCGCTCATCGCACAACTGTTTATGATCTATTACGGCCTGCCGCAG
TTTGGTATCGAATTAGATCCCATTCCGTCAGCAATGATTGGTCTGTCGCTGAACACTGCCGCCTATGCCGCCGAAACGCT
GCGCGCCGCCATTTCTTCTATTGATAAAGGTCAGTGGGAAGCCGCTGCCAGTATTGGTATGACGCCGTGGCAGACCATGC
GTCGCGCGATTTTGCCACAGGCGGCGCGGGTGGCGTTGCCGCCGCTGTCGAACAGCTTTATCAGTCTGGTAAAAGATACG
TCGCTGGCCGCGACAATCCAGGTGCCGGAGCTGTTCCGCCAGGCGCAGTTGATTACCTCGCGCACGCTGGAGGTGTTCAC
CATGTACCTGGCGGCTTCGCTCATCTACTGGATCATGGCGACAGTATTATCGACGTTGCAGAACCATTTTGAGAATCAAC
TTAATCGCCAGGAGAGAGAACCAAAATGA

Upstream 100 bases:

>100_bases
CAGAAACGCTTCAAAGATGAAGGGCCGATTCTGTTTATTCATACCGGCGGCGCGCCTGCGCTGTTCGCCTATCATCCCAC
GTTTAGCTCCGGGAACGCTC

Downstream 100 bases:

>100_bases
GTGCCATTGAAGTTAAGAACCTGGTGAAAAAATTTCACGGTCAGACGGTGCTGCACGGTATCGACCTCGAGGTAAAGCCT
GGCGAAGTGGTGGCAATTAT

Product: L-cystine ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MQESIQLVIDSLPFLLKGAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWMARFYISIFRGTPLIAQLFMIYYGLPQ
FGIELDPIPSAMIGLSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTPWQTMRRAILPQAARVALPPLSNSFISLVKDT
SLAATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSTLQNHFENQLNRQEREPK

Sequences:

>Translated_222_residues
MQESIQLVIDSLPFLLKGAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWMARFYISIFRGTPLIAQLFMIYYGLPQ
FGIELDPIPSAMIGLSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTPWQTMRRAILPQAARVALPPLSNSFISLVKDT
SLAATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSTLQNHFENQLNRQEREPK
>Mature_222_residues
MQESIQLVIDSLPFLLKGAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWMARFYISIFRGTPLIAQLFMIYYGLPQ
FGIELDPIPSAMIGLSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTPWQTMRRAILPQAARVALPPLSNSFISLVKDT
SLAATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSTLQNHFENQLNRQEREPK

Specific function: Probably part of the binding-protein-dependent transport system yecCS for an amino acid; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=222, Percent_Identity=99.5495495495496, Blast_Score=443, Evalue=1e-126,
Organism=Escherichia coli, GI1787030, Length=207, Percent_Identity=36.231884057971, Blast_Score=135, Evalue=1e-33,
Organism=Escherichia coli, GI1786873, Length=214, Percent_Identity=37.3831775700935, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1787086, Length=221, Percent_Identity=33.0316742081448, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1787087, Length=232, Percent_Identity=30.6034482758621, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87082239, Length=205, Percent_Identity=38.0487804878049, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1788645, Length=213, Percent_Identity=34.2723004694836, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1786874, Length=198, Percent_Identity=32.3232323232323, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788646, Length=199, Percent_Identity=30.1507537688442, Blast_Score=91, Evalue=4e-20,
Organism=Escherichia coli, GI48994930, Length=171, Percent_Identity=35.0877192982456, Blast_Score=80, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24820; Mature: 24820

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQESIQLVIDSLPFLLKGAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWMARFYIS
CCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IFRGTPLIAQLFMIYYGLPQFGIELDPIPSAMIGLSLNTAAYAAETLRAAISSIDKGQWE
HHCCCHHHHHHHHHHHCCCHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHH
AAASIGMTPWQTMRRAILPQAARVALPPLSNSFISLVKDTSLAATIQVPELFRQAQLITS
HHHHCCCCHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHCHHHEEEHHHHHHHHHHHHHH
RTLEVFTMYLAASLIYWIMATVLSTLQNHFENQLNRQEREPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQESIQLVIDSLPFLLKGAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWMARFYIS
CCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IFRGTPLIAQLFMIYYGLPQFGIELDPIPSAMIGLSLNTAAYAAETLRAAISSIDKGQWE
HHCCCHHHHHHHHHHHCCCHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHH
AAASIGMTPWQTMRRAILPQAARVALPPLSNSFISLVKDTSLAATIQVPELFRQAQLITS
HHHHCCCCHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHCHHHEEEHHHHHHHHHHHHHH
RTLEVFTMYLAASLIYWIMATVLSTLQNHFENQLNRQEREPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]