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The map label for this gene is wzzB [H]

Identifier: 157156091

GI number: 157156091

Start: 2279985

End: 2281019

Strand: Reverse

Name: wzzB [H]

Synonym: EcE24377A_2318

Alternate gene names: 157156091

Gene position: 2281019-2279985 (Counterclockwise)

Preceding gene: 157154758

Following gene: 157159460

Centisome position: 45.81

GC content: 47.63

Gene sequence:

>1035_bases
ATGGCGATTATCGCTAAACTATGGCGACTTAAAATTATTTCGTCCGTTAGGGTAATGATGAGAGTAGAAAATAATAATGT
TTCTGGGCAAAACCATGACCCGGAACAGATTGATTTGATTGATTTACTGGTGCAGTTGTGGCGTGGCAAGATGACAATTA
TCATCTCTGTCATTGTGGCTATTGCCCTGGCTATAGGGTATCTGGCCGTTGCCAAAGAAAAGTGGACTTCCACAGCTATC
GTTACTCAACCTGATGTGGGGCAAATCGCTGGTTATACCAACGCGATGAATGTGATTTACGGTCCGGCTGTACCGAAAGT
CTCCGACATTCAGGCTTCACTTATCGGACGTTACAGCACTGCATTCTCAGCATTAGCGGAAACGCTGGATAACCAGGAAG
AAGCAGAGAAGCTGACCATTGAGCCTACCGTTAAAAACCAGCCGTTACCACTGGCGGTGTCTTATGTTGGTGAAACACCT
GAAGGTGCGCAGAAGCAGCTGGCGAAGTATATCCAGCAAGTTGACGACCAGGTAAACGAAGAACTGGAAAAAGACCTGAA
AGACAACATCGCGCTGCGTATGAAAAACTTGCAGGATTCGCTGAAGACCCAGGAAGTGGTTGCGCAGGAGCAGAAAGATC
TGCGTATCCGTCAGATTCAGGAAGCGTTGCAGTATGCGAATCAGGCGCAGGTGACAAAGCCACAGGTTCAGCAGACTGAA
GATGTGACGCAAGATACGTTGTTCCTTTTGGGGAGCGAAGCTCTGGAGTCGATGATTAAGCATGAGGCGACTCGTCCGTT
AGTGTTCTCACCAAACTACTATCAGACACGTCAAAACCTGCTGGATATCGAAAACTTAAAGGTTGATGATCTTGATATTC
ATGCTTACCGTTATGTGATGAAACCGACGTTACCTATTCGTCGCGATAGCCCGAAAAAGGCAATTACCTTGATTCTGGCG
GTGCTGCTGGGCGGCATGGTTGGCGCGGGGATTGTCTTGGGGCGTAACGCTCTGCGTAATTACAACGCGAAGTAA

Upstream 100 bases:

>100_bases
GCAGCGACTAACATCATGTTATCAGGGCGATTTTCGCCCTGATTCTCTTATGTTCCCTTTGTAATAATTCATTATTTTTA
TCATTTATCCTATAGCATTC

Downstream 100 bases:

>100_bases
TCTTTTCGGTTTTAAAGAAAAAGGGCAGGGTGGTGACACCTTGCCCGTTTTTTTTTCCGGATGCTACAACAATATCGCAT
CCGCTTACCCCGCAACTCAC

Product: chain length determinant protein

Products: NA

Alternate protein names: Polysaccharide antigen chain regulator [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MAIIAKLWRLKIISSVRVMMRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAI
VTQPDVGQIAGYTNAMNVIYGPAVPKVSDIQASLIGRYSTAFSALAETLDNQEEAEKLTIEPTVKNQPLPLAVSYVGETP
EGAQKQLAKYIQQVDDQVNEELEKDLKDNIALRMKNLQDSLKTQEVVAQEQKDLRIRQIQEALQYANQAQVTKPQVQQTE
DVTQDTLFLLGSEALESMIKHEATRPLVFSPNYYQTRQNLLDIENLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILA
VLLGGMVGAGIVLGRNALRNYNAK

Sequences:

>Translated_344_residues
MAIIAKLWRLKIISSVRVMMRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAI
VTQPDVGQIAGYTNAMNVIYGPAVPKVSDIQASLIGRYSTAFSALAETLDNQEEAEKLTIEPTVKNQPLPLAVSYVGETP
EGAQKQLAKYIQQVDDQVNEELEKDLKDNIALRMKNLQDSLKTQEVVAQEQKDLRIRQIQEALQYANQAQVTKPQVQQTE
DVTQDTLFLLGSEALESMIKHEATRPLVFSPNYYQTRQNLLDIENLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILA
VLLGGMVGAGIVLGRNALRNYNAK
>Mature_343_residues
AIIAKLWRLKIISSVRVMMRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIV
TQPDVGQIAGYTNAMNVIYGPAVPKVSDIQASLIGRYSTAFSALAETLDNQEEAEKLTIEPTVKNQPLPLAVSYVGETPE
GAQKQLAKYIQQVDDQVNEELEKDLKDNIALRMKNLQDSLKTQEVVAQEQKDLRIRQIQEALQYANQAQVTKPQVQQTED
VTQDTLFLLGSEALESMIKHEATRPLVFSPNYYQTRQNLLDIENLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILAV
LLGGMVGAGIVLGRNALRNYNAK

Specific function: Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111/M92) and o

COG id: COG3765

COG function: function code M; Chain length determinant protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the wzzB/cld/rol family [H]

Homologues:

Organism=Escherichia coli, GI87082029, Length=326, Percent_Identity=91.4110429447853, Blast_Score=585, Evalue=1e-168,
Organism=Escherichia coli, GI87082332, Length=332, Percent_Identity=25.9036144578313, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1786802, Length=345, Percent_Identity=27.536231884058, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003856 [H]

Pfam domain/function: PF02706 Wzz [H]

EC number: NA

Molecular weight: Translated: 38445; Mature: 38314

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIIAKLWRLKIISSVRVMMRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIISVIVA
CHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
IALAIGYLAVAKEKWTSTAIVTQPDVGQIAGYTNAMNVIYGPAVPKVSDIQASLIGRYST
HHHHHHHHHHHHHHHCCEEEEECCCHHHHHCCHHHHHHEECCCCCCHHHHHHHHHHHHHH
AFSALAETLDNQEEAEKLTIEPTVKNQPLPLAVSYVGETPEGAQKQLAKYIQQVDDQVNE
HHHHHHHHHCCHHHHHHEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
ELEKDLKDNIALRMKNLQDSLKTQEVVAQEQKDLRIRQIQEALQYANQAQVTKPQVQQTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
DVTQDTLFLLGSEALESMIKHEATRPLVFSPNYYQTRQNLLDIENLKVDDLDIHAYRYVM
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
KPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLGRNALRNYNAK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AIIAKLWRLKIISSVRVMMRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIISVIVA
HHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
IALAIGYLAVAKEKWTSTAIVTQPDVGQIAGYTNAMNVIYGPAVPKVSDIQASLIGRYST
HHHHHHHHHHHHHHHCCEEEEECCCHHHHHCCHHHHHHEECCCCCCHHHHHHHHHHHHHH
AFSALAETLDNQEEAEKLTIEPTVKNQPLPLAVSYVGETPEGAQKQLAKYIQQVDDQVNE
HHHHHHHHHCCHHHHHHEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
ELEKDLKDNIALRMKNLQDSLKTQEVVAQEQKDLRIRQIQEALQYANQAQVTKPQVQQTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
DVTQDTLFLLGSEALESMIKHEATRPLVFSPNYYQTRQNLLDIENLKVDDLDIHAYRYVM
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
KPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLGRNALRNYNAK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9383197 [H]