Click here to switch to the map view.

The map label for this gene is moeB [H]

Identifier: 156980591

GI number: 156980591

Start: 2402974

End: 2403978

Strand: Reverse

Name: moeB [H]

Synonym: SAHV_2260

Alternate gene names: 156980591

Gene position: 2403978-2402974 (Counterclockwise)

Preceding gene: 156980592

Following gene: 156980590

Centisome position: 83.47

GC content: 34.83

Gene sequence:

>1005_bases
GTGAGTCAAGAACGTTATTCAAGGCAAATTTTATTTAAACAAATAGGTGAAATAGGTCAAAGCAAAATAAATCAAAAATG
TGCGTTGATTATTGGTATGGGCGCATTAGGTACACATGTGGCCGAAGGACTTGTTAGAGCAGGCATTGCTAAACTAATCA
TTGTTGATAGAGATTATATTGAATTTAGTAATTTACAAAGACAAACATTGTTTACTGAAGAAGATGCTTTGAAAATGATG
CCTAAAGTGGTTGCAGCTAAAAAGCATTTGCTAGCGTTACGTAGTGATGTTGATATTGATGGTTGTATTGCCCATGTGGA
TTATTATTTTTTGGAAACACATGGACAGGACGTTGACGTTATTATTGATGCAACCGATAACTTTGAAACACGACAACTGA
TTAATGATTTTGCATATAAACATCGTATACCTTGGATTTATGGTGGTGTTGTACAGAGTACATATACAGAAGCTGCATTT
ATACCTGGTAAAACACCTTGCTTTAACTGTTTGGTACCACAATTGCCAGCATTAAATTTAACATGTGATACAGTAGGGGT
CATTCAACCTGCCGTGACGATGGCAACAAGTTTACAATTAAGAGATGCGATGAAAGTATTAACGGAACAACCAATTGACA
CAAAAATAACTTATGGCGATATTTGGGAAGGTAGTCATTATTCATTTGGTTTCAGTAAAATGCAACGTTCAGACTGTACA
ACTTGTGGAGATGTACCAAGTTATCCGTATTTAAACAAGAATGAACAACGTTATGCAACATTGTGTGGTAGAGACACTGT
ACAGTATGAAAATGCATCAATTACACACGACATTCTTGTTCAATTTTTAAAACAACATCAACTAAATTATCGCAGTAATT
CGTATATGGTTATGTTTGAATTTAAAGGACACCGCATTGTTGCTTTTAAAGGTGGAAGGTTTTTAATACATGGCATGACA
CGCACATCAGATGCCACACATCTAATGAATTTATTGTTTGGATAA

Upstream 100 bases:

>100_bases
TTAATGATGTTTTAAACTCTTTTTTAGGGGCAGTTTTTTTGAGAGACATTGACGCGCGTCATATAATGAAAGTAATGATA
AAAAGAAAGGATAACTTAAT

Downstream 100 bases:

>100_bases
AAAAAGATAAGACAAAAGGAGTGTAATATTATGGGCGAACATCAAAACGTTAAATTGAATCGTACAGTTAAAGCAGCCGT
ACTAACGGTATCAGATACTA

Product: molybdopterin biosynthesis protein

Products: NA

Alternate protein names: MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMM
PKVVAAKKHLLALRSDVDIDGCIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAF
IPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCT
TCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMT
RTSDATHLMNLLFG

Sequences:

>Translated_334_residues
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMM
PKVVAAKKHLLALRSDVDIDGCIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAF
IPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCT
TCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMT
RTSDATHLMNLLFG
>Mature_333_residues
SQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMP
KVVAAKKHLLALRSDVDIDGCIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFI
PGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCTT
CGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTR
TSDATHLMNLLFG

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=257, Percent_Identity=29.1828793774319, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI13376212, Length=248, Percent_Identity=27.0161290322581, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1787048, Length=244, Percent_Identity=30.327868852459, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082356, Length=247, Percent_Identity=33.1983805668016, Blast_Score=106, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17540406, Length=248, Percent_Identity=30.6451612903226, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17508819, Length=183, Percent_Identity=31.6939890710383, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321903, Length=277, Percent_Identity=25.2707581227437, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6320598, Length=170, Percent_Identity=28.8235294117647, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24582879, Length=254, Percent_Identity=29.5275590551181, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24641311, Length=190, Percent_Identity=33.1578947368421, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 37777; Mature: 37646

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYI
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCEEEEEEECCHH
EFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDGCIAHVDYYFLETHGQDVDV
HHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEEECCCCEEE
IIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNL
EEECCCCHHHHHHHHHHHHHHCCCEEECCHHHHHCCCEEECCCCCCHHHHHCCCCCCCEE
TCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCT
EECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHCCCC
TCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFE
CCCCCCCCCCCCCCCHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEEEE
FKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
ECCCEEEEEECCEEEEEECCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYI
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCEEEEEEECCHH
EFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDGCIAHVDYYFLETHGQDVDV
HHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEEECCCCEEE
IIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNL
EEECCCCHHHHHHHHHHHHHHCCCEEECCHHHHHCCCEEECCCCCCHHHHHCCCCCCCEE
TCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCT
EECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHCCCC
TCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFE
CCCCCCCCCCCCCCCHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEEEE
FKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
ECCCEEEEEECCEEEEEECCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]