Click here to switch to the map view.

The map label for this gene is moeA [H]

Identifier: 156980588

GI number: 156980588

Start: 2400619

End: 2401878

Strand: Reverse

Name: moeA [H]

Synonym: SAHV_2257

Alternate gene names: 156980588

Gene position: 2401878-2400619 (Counterclockwise)

Preceding gene: 156980590

Following gene: 156980587

Centisome position: 83.39

GC content: 37.86

Gene sequence:

>1260_bases
ATGGTAGTAGAAAAAAGAAACCCAATCCCAGTTAAAGAAGCAATTCAACGTATCGTTAATCAGCAGAGTTCAATGCCGGC
AATTACGGTAGCACTTGAAAAAAGTCTAAATCATATCTTAGCAGAAGATATTGTAGCTACTTATGATATACCAAGGTTTG
ATAAATCACCTTATGATGGTTTTGCAATTCGCAGTGTTGATTCACAAGGGGCAAGTGGTCAGAATCGCATTGAGTTTAAA
GTGATTGATCATATTGGTGCAGGTTCAGTTTCTGATAAATTAGTTGGGGATCACGAAGCGGTGCGTATTATGACTGGAGC
ACAAATACCAAATGGCGCAGATGCTGTTGTTATGTTTGAACAAACGATTGAACTAGAAGATACATTTACAATTCGTAAAC
CATTTTCAAAAAATGAAAATATATCTTTAAAAGGTGAAGAAACAAAGACAGGCGATGTTGTTCTAAAAAAAGGACAAGTA
ATTAACCCAGGGGCTATCGCGGTCCTTGCAACATATGGCTATGCAGAGGTTAAAGTTATTAAGCAACCGAGTGTCGCTGT
TATTGCAACAGGAAGCGAATTATTAGATGTTAATGATGTATTAGAAGATGGAAAAATTCGTAACTCTAATGGCCCAATGA
TTCGTGCCTTAGCAGAAAAATTAGGTCTTGAAGTTGGTATTTACAAAACACAAAAAGATGATTTAGATAGTGGCATCCAA
GTCGTTAAAGAAGCTATGGAAAAACACGATATCGTTATTACAACGGGTGGAGTTTCTGTTGGAGACTTTGACTATTTACC
TGAGATTTATAAGGCTGTAAAGGCGGAAGTGTTATTTAATAAAGTAGCAATGCGTCCTGGTAGCGTAACAACGGTTGCAT
TTGCAGATGGAAAGTATTTGTTTGGATTATCTGGAAATCCATCAGCTTGTTTTACAGGATTTGAACTATTTGTGAAACCA
GCTGTTAAACATATGTGTGGCGCACTAGAAGTCTTCCCGCAAATAATTAAAGCAACATTAATGGAAGATTTTACCAAGGC
AAACCCATTCACACGATTTATACGTGCTAAAGCAACGTTAACAAGTGCTGGAGCTACTGTAGTACCTTCAGGATTCAATA
AATCAGGTGCGGTTGTAGCGATTGCACATGCTAACTGTATGGTCATGTTACCAGGAGGGTCACGTGGTTTTAAAGCGGGG
CATACAGTAGATATTATATTGACTGAATCTGACGCTGCTGAAGAGGAACTTCTTTTATGA

Upstream 100 bases:

>100_bases
GCGTGGCCTTGTTGATTAATATGAGTAAACTCAGTCATTTTACCCCTCCTAGTGCATCTAGTATATCATGAAAAAATAAA
AGTTTTGGAGATGATTTTTA

Downstream 100 bases:

>100_bases
TTTTACAAATTGTAGGTTACAAAAAGTCTGGTAAGACAACATTGATGAGGCATATTGTCTCTTTCTTAAAGACACATGGT
TATACAGTTGCTACTATTAA

Product: molybdopterin biosynthesis protein

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFK
VIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQV
INPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQ
VVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFADGKYLFGLSGNPSACFTGFELFVKP
AVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAG
HTVDIILTESDAAEEELLL

Sequences:

>Translated_419_residues
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFK
VIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQV
INPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQ
VVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFADGKYLFGLSGNPSACFTGFELFVKP
AVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAG
HTVDIILTESDAAEEELLL
>Mature_419_residues
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFK
VIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQV
INPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQ
VVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFADGKYLFGLSGNPSACFTGFELFVKP
AVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAG
HTVDIILTESDAAEEELLL

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=401, Percent_Identity=33.9152119700748, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI10880983, Length=401, Percent_Identity=33.9152119700748, Blast_Score=182, Evalue=4e-46,
Organism=Escherichia coli, GI1787049, Length=299, Percent_Identity=34.1137123745819, Blast_Score=155, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI25147659, Length=342, Percent_Identity=30.9941520467836, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17562606, Length=378, Percent_Identity=26.7195767195767, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI17136978, Length=398, Percent_Identity=29.3969849246231, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24638841, Length=398, Percent_Identity=29.3969849246231, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 44989; Mature: 44989

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDG
CCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
FAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFE
EEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEE
QTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVI
EEECCCCEEEEECCCCCCCCEEEECCCCCCCCEEEECCCEECCCCEEEEEECCCEEEEEE
KQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQ
ECCCEEEEECCCHHCCHHHHHCCCEEECCCCCHHHHHHHHHCCEEEEEECCCCCHHHHHH
VVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFADGKYL
HHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEE
FGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATL
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEE
TSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
ECCCCEEECCCCCCCCCEEEEEECCEEEEECCCCCCCCCCCEEEEEEECCCCCCHHCCC
>Mature Secondary Structure
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDG
CCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
FAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFE
EEEEECCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEE
QTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVI
EEECCCCEEEEECCCCCCCCEEEECCCCCCCCEEEECCCEECCCCEEEEEECCCEEEEEE
KQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQ
ECCCEEEEECCCHHCCHHHHHCCCEEECCCCCHHHHHHHHHCCEEEEEECCCCCHHHHHH
VVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFADGKYL
HHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEE
FGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATL
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEE
TSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
ECCCCEEECCCCCCCCCEEEEEECCEEEEECCCCCCCCCCCEEEEEEECCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA