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The map label for this gene is 156937277

Identifier: 156937277

GI number: 156937277

Start: 432244

End: 433002

Strand: Reverse

Name: 156937277

Synonym: Igni_0483

Alternate gene names: NA

Gene position: 433002-432244 (Counterclockwise)

Preceding gene: 156937280

Following gene: 156937274

Centisome position: 33.37

GC content: 55.07

Gene sequence:

>759_bases
TTGCGCGCGAGGCCAGAGGCTATTGATGAAAGGATGCGCGTGCCGCTGTACGTCGAGGCCTCGAAGCTCACTGTAGTCGT
GTTCGGAGGGGGCAAGGTGGGCACCAGGAGGGCGCAGAAGTTTGCCAACGCGGGAGCGCGGGTGAGGGTCGTCGCTAAGG
AGTTCAGTGAGGACCTTTATTATTTGAACGTAGAACTGGTTAAGTCCGACCTAGAGAGGGAAGATGAAATAAGGAAGCTC
ATTGAGGACGCCGACATAGTTGTAATAGCGACAAACAATAAAGAGGTGAACGACAAGATATTTAGAATTGCTAAGGAGAT
GGGGAAACTGGTCAACGACGCCACCGAGGCCTCCCGCAGCGACGTCCACGTGCCCTTCGAGGCGGAGGTGGACGGGATAA
GGATAGCGGTGACCAGCGAGGGGGCCTCCGGCGTCGCCGCTCACGTGGCGCTCGCACTAATTGAGAGGTGCTTGAAGAGC
AACGAATTCTTCAAGAGGATAAACGAGTTTGCCAGGAGGTTCAAGCGAGAGCTCAAGGAACTCATAGACGACCCCAAGAG
GAGGTTCGGGCTCTACTGGTACGTGATGTTGCAGAGGGACATAATCGAGATGGTGAGGGAGGGCAAGATAGACGAAGCCT
TAGAGAAGGCCTTAGCTATAGCTAAGAGCTACGAAGGCGAGGGGATGACGGACGTCAAGTACGCTCTCGGGAAGTTTCTC
GAAGAATGGGGCGACGAGCTACTAAGAGCGTGGCCTTGA

Upstream 100 bases:

>100_bases
CACGTTAGACCCCGAGCGTTAATTCGAGCCGCCCCTTAAAGGTCGGTGTCTAACGCTCTGTTCGGCAATAGCCCGGATAC
ATCAGAGGAACACGTTAAAT

Downstream 100 bases:

>100_bases
CCCCGGGCGGGTCGAAGAATGTTATCTCCAGCTTGTTCCCCCTCGCCACGTACAAGTTATACGTAGAAGGGCTCCACCAG
ACGGAGGTTGCGTTGCTTAC

Product: siroheme synthase

Products: sirohydrochlorin; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MRARPEAIDERMRVPLYVEASKLTVVVFGGGKVGTRRAQKFANAGARVRVVAKEFSEDLYYLNVELVKSDLEREDEIRKL
IEDADIVVIATNNKEVNDKIFRIAKEMGKLVNDATEASRSDVHVPFEAEVDGIRIAVTSEGASGVAAHVALALIERCLKS
NEFFKRINEFARRFKRELKELIDDPKRRFGLYWYVMLQRDIIEMVREGKIDEALEKALAIAKSYEGEGMTDVKYALGKFL
EEWGDELLRAWP

Sequences:

>Translated_252_residues
MRARPEAIDERMRVPLYVEASKLTVVVFGGGKVGTRRAQKFANAGARVRVVAKEFSEDLYYLNVELVKSDLEREDEIRKL
IEDADIVVIATNNKEVNDKIFRIAKEMGKLVNDATEASRSDVHVPFEAEVDGIRIAVTSEGASGVAAHVALALIERCLKS
NEFFKRINEFARRFKRELKELIDDPKRRFGLYWYVMLQRDIIEMVREGKIDEALEKALAIAKSYEGEGMTDVKYALGKFL
EEWGDELLRAWP
>Mature_252_residues
MRARPEAIDERMRVPLYVEASKLTVVVFGGGKVGTRRAQKFANAGARVRVVAKEFSEDLYYLNVELVKSDLEREDEIRKL
IEDADIVVIATNNKEVNDKIFRIAKEMGKLVNDATEASRSDVHVPFEAEVDGIRIAVTSEGASGVAAHVALALIERCLKS
NEFFKRINEFARRFKRELKELIDDPKRRFGLYWYVMLQRDIIEMVREGKIDEALEKALAIAKSYEGEGMTDVKYALGKFL
EEWGDELLRAWP

Specific function: Unknown

COG id: COG1648

COG function: function code H; Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011128
- InterPro:   IPR016040
- InterPro:   IPR006367 [H]

Pfam domain/function: PF01210 NAD_Gly3P_dh_N [H]

EC number: 1.3.1.76; 4.99.1.4

Molecular weight: Translated: 28759; Mature: 28759

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRARPEAIDERMRVPLYVEASKLTVVVFGGGKVGTRRAQKFANAGARVRVVAKEFSEDLY
CCCCCHHHHHHCCCCEEEEECCEEEEEECCCCCCHHHHHHHHCCCCEEEHHHHHHCCCCE
YLNVELVKSDLEREDEIRKLIEDADIVVIATNNKEVNDKIFRIAKEMGKLVNDATEASRS
EEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC
DVHVPFEAEVDGIRIAVTSEGASGVAAHVALALIERCLKSNEFFKRINEFARRFKRELKE
CCCCCEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LIDDPKRRFGLYWYVMLQRDIIEMVREGKIDEALEKALAIAKSYEGEGMTDVKYALGKFL
HHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
EEWGDELLRAWP
HHHHHHHHHHCC
>Mature Secondary Structure
MRARPEAIDERMRVPLYVEASKLTVVVFGGGKVGTRRAQKFANAGARVRVVAKEFSEDLY
CCCCCHHHHHHCCCCEEEEECCEEEEEECCCCCCHHHHHHHHCCCCEEEHHHHHHCCCCE
YLNVELVKSDLEREDEIRKLIEDADIVVIATNNKEVNDKIFRIAKEMGKLVNDATEASRS
EEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC
DVHVPFEAEVDGIRIAVTSEGASGVAAHVALALIERCLKSNEFFKRINEFARRFKRELKE
CCCCCEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LIDDPKRRFGLYWYVMLQRDIIEMVREGKIDEALEKALAIAKSYEGEGMTDVKYALGKFL
HHHCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
EEWGDELLRAWP
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 2; NAD+

Specific reaction: precorrin-2 + NAD+ = sirohydrochlorin + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]