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The map label for this gene is lysS [H]

Identifier: 156937259

GI number: 156937259

Start: 412003

End: 413493

Strand: Reverse

Name: lysS [H]

Synonym: Igni_0465

Alternate gene names: 156937259

Gene position: 413493-412003 (Counterclockwise)

Preceding gene: 156937262

Following gene: 156937249

Centisome position: 31.87

GC content: 57.21

Gene sequence:

>1491_bases
GTGGAGTGGTTGAACAAGATCGTCGACGAGATAATAAAGAAAAGGGGCGGTAGGGCCTTCGTAGTGGCGTCGGGGCTCAC
CACCTCCGGACCGGCCCACTTGGGGACCTTGAGCGAGTTCATCTACCCCTACTCCATAGTCCAAGAGCTCCGCCGGAGGG
GCTACGACGCCGAGTTCGTCTTCGTGGCGGACATAATGGACGCTTTCGACGACATCCCCCAAACTCTGAAGGACAAGGAA
GAGGAGCTGAAAAAGCACTTGGGCAAGCCCTTGGCGGAGGTGCCGGACCCCTACGGGTGTCACGAGAGCTACGGCGAGCA
CTTCCTCGCGGAGTTCTTGGAACTCATGGACAAGTTCGGCATAAAGCCGGACGAGGTGTTGAGGGCGAGCGAGCTCTATG
CCCAAGGCTGGTACGACGACTACTTGAGGCTCTTCGTGGAGCAGCGCGACAAAGTGAAGAAAATTATGGAGGAGACGGCG
ATGAGGAAGCTGCCGGACGACTGGTGGGGCTTCGTCAAGCCTATTTGTGAGAAGTGCGGTAGGATAGACAAAACCGTAGT
GAAGAAGGTAGAGGGCGACAAGATATATTACAAGTGCGAGGCCTGCGGCCACGAGGGGGCTGTAGAAGTCTCCTCTCACC
GCTGGAAGCTCGCTTGGAGGCTCGACTGGCCCTCTAGGCAAGACTTCTTGGGGGTGGACGCGGAGGGCGGAGGGGTAGAC
CACTTCACCAAGGGAGGCTCGTGGGATACGGCGAAGAGGATCCACAAGGAGGTCTTCGGGAAGGAGCCGCCGGTGGGCTT
CCGCTACGGCTTCGTGTTGATGAACGGAAAAAAGATGAGCAAGAGCAAGGGCATAGGCGCCTTACACGAGATAATGGCCC
TCCTCCACCCTTCAGTGATAATGTACTTTATACTTAAGCACGATATAAAGGAAAACAAAAACTTCAAGATGGACCCGAGG
TTCCTCATGCAGCTCTACGAGGAGTACCGGAGGGTGGCCTTGGGCGAGGACGAGGACCCCAAGAGGAGGAGGGCTTGGGA
GCTGAGCGGGGGAAGGGTCTGGAGGGCCGGCTTCGCGGACTTGCTGGTCTACTACCAGATATACCGGGACTGGAAGAAGG
TCGGGGAGCTCACCGGAGATCCCCAAGCAGTGAAGGACTTGGCCCCTTACGTGGAGGAGTGGGTCAAGAGGGGCTTCGTG
CCCGAGGAGTACGAGGTTACGGTCAAGCAAGGCAAGGTCAGCGACCCTAAGGGCTGCGAGTTCTTGAGGGCGCTCGCGGA
GGAGTTAAGGGAAGACATGGACGCGGTGGAAATACACAACAAGGTGTATGAGGTCGCCAAGAAAGTAGGCCTAAGCCCCA
AGGATGCCTTCAAGTTCGTCTATAAGGCCTTGCTAGATAAGGAGCGCGGGCCCAGGGCGGGGAGACTCATAAAAGCGATA
GGCGTTAGGAAGGCTAAGGAGATGTTCGAGAAAGCTTGCTCCCCTACATAG

Upstream 100 bases:

>100_bases
ACTCTTTTTTCACCCGTGGAGTCTCAAAAGAGGATAGGAAGAAAAGGAGAGACGACAAGGGCTTCAAGCTCTCCCTCTGA
AGTTCCTCCCGGTGCGCGCT

Downstream 100 bases:

>100_bases
GCAAGGGGAGGACGCTCCCGAAGCCCAGCTCCGCGAGCTCCCCCACCCCGCGCCAGTAGAGCTCCTCGGGTGAGACCTCT
AGCGTCCCCACGACCGCGGA

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS [H]

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MEWLNKIVDEIIKKRGGRAFVVASGLTTSGPAHLGTLSEFIYPYSIVQELRRRGYDAEFVFVADIMDAFDDIPQTLKDKE
EELKKHLGKPLAEVPDPYGCHESYGEHFLAEFLELMDKFGIKPDEVLRASELYAQGWYDDYLRLFVEQRDKVKKIMEETA
MRKLPDDWWGFVKPICEKCGRIDKTVVKKVEGDKIYYKCEACGHEGAVEVSSHRWKLAWRLDWPSRQDFLGVDAEGGGVD
HFTKGGSWDTAKRIHKEVFGKEPPVGFRYGFVLMNGKKMSKSKGIGALHEIMALLHPSVIMYFILKHDIKENKNFKMDPR
FLMQLYEEYRRVALGEDEDPKRRRAWELSGGRVWRAGFADLLVYYQIYRDWKKVGELTGDPQAVKDLAPYVEEWVKRGFV
PEEYEVTVKQGKVSDPKGCEFLRALAEELREDMDAVEIHNKVYEVAKKVGLSPKDAFKFVYKALLDKERGPRAGRLIKAI
GVRKAKEMFEKACSPT

Sequences:

>Translated_496_residues
MEWLNKIVDEIIKKRGGRAFVVASGLTTSGPAHLGTLSEFIYPYSIVQELRRRGYDAEFVFVADIMDAFDDIPQTLKDKE
EELKKHLGKPLAEVPDPYGCHESYGEHFLAEFLELMDKFGIKPDEVLRASELYAQGWYDDYLRLFVEQRDKVKKIMEETA
MRKLPDDWWGFVKPICEKCGRIDKTVVKKVEGDKIYYKCEACGHEGAVEVSSHRWKLAWRLDWPSRQDFLGVDAEGGGVD
HFTKGGSWDTAKRIHKEVFGKEPPVGFRYGFVLMNGKKMSKSKGIGALHEIMALLHPSVIMYFILKHDIKENKNFKMDPR
FLMQLYEEYRRVALGEDEDPKRRRAWELSGGRVWRAGFADLLVYYQIYRDWKKVGELTGDPQAVKDLAPYVEEWVKRGFV
PEEYEVTVKQGKVSDPKGCEFLRALAEELREDMDAVEIHNKVYEVAKKVGLSPKDAFKFVYKALLDKERGPRAGRLIKAI
GVRKAKEMFEKACSPT
>Mature_496_residues
MEWLNKIVDEIIKKRGGRAFVVASGLTTSGPAHLGTLSEFIYPYSIVQELRRRGYDAEFVFVADIMDAFDDIPQTLKDKE
EELKKHLGKPLAEVPDPYGCHESYGEHFLAEFLELMDKFGIKPDEVLRASELYAQGWYDDYLRLFVEQRDKVKKIMEETA
MRKLPDDWWGFVKPICEKCGRIDKTVVKKVEGDKIYYKCEACGHEGAVEVSSHRWKLAWRLDWPSRQDFLGVDAEGGGVD
HFTKGGSWDTAKRIHKEVFGKEPPVGFRYGFVLMNGKKMSKSKGIGALHEIMALLHPSVIMYFILKHDIKENKNFKMDPR
FLMQLYEEYRRVALGEDEDPKRRRAWELSGGRVWRAGFADLLVYYQIYRDWKKVGELTGDPQAVKDLAPYVEEWVKRGFV
PEEYEVTVKQGKVSDPKGCEFLRALAEELREDMDAVEIHNKVYEVAKKVGLSPKDAFKFVYKALLDKERGPRAGRLIKAI
GVRKAKEMFEKACSPT

Specific function: Unknown

COG id: COG1384

COG function: function code J; Lysyl-tRNA synthetase (class I)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR000924
- InterPro:   IPR002904
- InterPro:   IPR020754
- InterPro:   IPR020756
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01921 tRNA-synt_1f [H]

EC number: =6.1.1.6 [H]

Molecular weight: Translated: 57237; Mature: 57237

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWLNKIVDEIIKKRGGRAFVVASGLTTSGPAHLGTLSEFIYPYSIVQELRRRGYDAEFV
CHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
FVADIMDAFDDIPQTLKDKEEELKKHLGKPLAEVPDPYGCHESYGEHFLAEFLELMDKFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHC
IKPDEVLRASELYAQGWYDDYLRLFVEQRDKVKKIMEETAMRKLPDDWWGFVKPICEKCG
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
RIDKTVVKKVEGDKIYYKCEACGHEGAVEVSSHRWKLAWRLDWPSRQDFLGVDAEGGGVD
CHHHHHHHHCCCCEEEEEEECCCCCCCEEECCCEEEEEEEECCCCCCCCEECCCCCCCCC
HFTKGGSWDTAKRIHKEVFGKEPPVGFRYGFVLMNGKKMSKSKGIGALHEIMALLHPSVI
CCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHH
MYFILKHDIKENKNFKMDPRFLMQLYEEYRRVALGEDEDPKRRRAWELSGGRVWRAGFAD
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCEECCCCCEEHHHHHH
LLVYYQIYRDWKKVGELTGDPQAVKDLAPYVEEWVKRGFVPEEYEVTVKQGKVSDPKGCE
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHEEEEECCCCCCCHHHH
FLRALAEELREDMDAVEIHNKVYEVAKKVGLSPKDAFKFVYKALLDKERGPRAGRLIKAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GVRKAKEMFEKACSPT
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEWLNKIVDEIIKKRGGRAFVVASGLTTSGPAHLGTLSEFIYPYSIVQELRRRGYDAEFV
CHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
FVADIMDAFDDIPQTLKDKEEELKKHLGKPLAEVPDPYGCHESYGEHFLAEFLELMDKFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHC
IKPDEVLRASELYAQGWYDDYLRLFVEQRDKVKKIMEETAMRKLPDDWWGFVKPICEKCG
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
RIDKTVVKKVEGDKIYYKCEACGHEGAVEVSSHRWKLAWRLDWPSRQDFLGVDAEGGGVD
CHHHHHHHHCCCCEEEEEEECCCCCCCEEECCCEEEEEEEECCCCCCCCEECCCCCCCCC
HFTKGGSWDTAKRIHKEVFGKEPPVGFRYGFVLMNGKKMSKSKGIGALHEIMALLHPSVI
CCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHH
MYFILKHDIKENKNFKMDPRFLMQLYEEYRRVALGEDEDPKRRRAWELSGGRVWRAGFAD
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCEECCCCCEEHHHHHH
LLVYYQIYRDWKKVGELTGDPQAVKDLAPYVEEWVKRGFVPEEYEVTVKQGKVSDPKGCE
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHEEEEECCCCCCCHHHH
FLRALAEELREDMDAVEIHNKVYEVAKKVGLSPKDAFKFVYKALLDKERGPRAGRLIKAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GVRKAKEMFEKACSPT
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]